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Thalassemia: Lessons in Perseverance and Compassion
As I reflect on my life with transfusion-dependent beta-thalassemia (thal), it is easy to become overwhelmed. In short, thalassemia is an inherited blood disorder where the body is unable to produce hemoglobin, which causes severe anemia and endless complications. In 1973, when I was diagnosed at 14
As I reflect on my life with transfusion-dependent beta-thalassemia (thal), it is easy to become overwhelmed. In short, thalassemia is an inherited blood disorder where the body is unable to produce hemoglobin, which causes severe anemia and endless complications. In 1973, when I was diagnosed at 14
AnnaHU
HealthUnlocked
in
HealthUnlocked Blog
7 months ago
Be Aware To Beware.....FYI
Medications To Be Avoided Or Used With Caution In Parkinson’s Disease The manufacturers of these medications may not list Parkinson’s disease as an absolute contraindication; however, better choices within a medication class may be suggested. Some of these medications alter the brain ‘s dopamine
Medications To Be Avoided Or Used With Caution In Parkinson’s Disease The manufacturers of these medications may not list Parkinson’s disease as an absolute contraindication; however, better choices within a medication class may be suggested. Some of these medications alter the brain ‘s dopamine
beehive23
in
Cure Parkinson's
7 months ago
Cortisol levels
Hello everyone, I have recently finally come off pramipexole after 6 months weaning off and I appear to be one of the lucky ones that the iron oral therapy has significantly helped my restless legs. However, I am still not sleeping well and have dipped into the hormonal debate… I think I have high cortisol
Hello everyone, I have recently finally come off pramipexole after 6 months weaning off and I appear to be one of the lucky ones that the iron oral therapy has significantly helped my restless legs. However, I am still not sleeping well and have dipped into the hormonal debate… I think I have high cortisol
Jukebox55
in
Restless Legs Syndrome
7 months ago
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Diagnosis at last! Haemochromotosis?
I've posted a few times on this forum but a bit of backstory - hubby, 43 had sudden onset of upper right quadrant pain last December, has some tests for gallstones, found nothing, immediately stopped drinking (had drunk heavily for around 15 years), and after a lot of back and forward was found to have
I've posted a few times on this forum but a bit of backstory - hubby, 43 had sudden onset of upper right quadrant pain last December, has some tests for gallstones, found nothing, immediately stopped drinking (had drunk heavily for around 15 years), and after a lot of back and forward was found to have
RugbyMama
in
British Liver Trust
7 months ago
racing pulse
hi thyroid community. Quick question…I’ve noticed since I’ve been taking Erfa that my pulse races quite often sometimes over 100. Especially when I’m climbing up hill or going up stairs for example. I’ve realised I’ve had this for quite a while (years) and had put it down to being breathless due to
hi thyroid community. Quick question…I’ve noticed since I’ve been taking Erfa that my pulse races quite often sometimes over 100. Especially when I’m climbing up hill or going up stairs for example. I’ve realised I’ve had this for quite a while (years) and had put it down to being breathless due to
Starseed56
in
Thyroid UK
7 months ago
Trying 3 Arrows Iron - UK Test Guide?
Hi I have been struggling to get my ferritin out of the long grass for years. I can force it up a bit now and then but I've never been optimal and often I'm well below optimal. I have come across the excellent SlowDragon posts on 3 Arrows and I'm going to give it a try, for various reasons. But on
Hi I have been struggling to get my ferritin out of the long grass for years. I can force it up a bit now and then but I've never been optimal and often I'm well below optimal. I have come across the excellent SlowDragon posts on 3 Arrows and I'm going to give it a try, for various reasons. But on
FancyPants54
in
Thyroid UK
7 months ago
First time posting here with questions
Hello, I was wondering how to tell if you need b12 injections when you take oral b12 and your serum b12 always comes out looking great? I haven't had it tested recently but past tests always come out way over the range. Anyway, I saw a post by @Marz in which she said that she takes b12 due to having
Hello, I was wondering how to tell if you need b12 injections when you take oral b12 and your serum b12 always comes out looking great? I haven't had it tested recently but past tests always come out way over the range. Anyway, I saw a post by @Marz in which she said that she takes b12 due to having
shirlzoni
in
Thyroid UK
4 months ago
Caffeic acid phenethyl ester (CAPE) is an ingredient in bee propolis. See below for invitro and mice evidence for inhibition AR-V7 by CAPE
Human studies needed. Caffeic acid phenethyl ester suppresses the expression of androgen receptor variant 7 via inhibition of CDK1 and AKT Ying-Yu Kuo, Chieh Huo, Chia-Yang Li & Chih-Pin Chuu Cancer Gene Therapy (2024) doi: 10.1038/s41417-024-00753-z Abstract Androgen receptor (AR) splice variant
Human studies needed. Caffeic acid phenethyl ester suppresses the expression of androgen receptor variant 7 via inhibition of CDK1 and AKT Ying-Yu Kuo, Chieh Huo, Chia-Yang Li & Chih-Pin Chuu Cancer Gene Therapy (2024) doi: 10.1038/s41417-024-00753-z Abstract Androgen receptor (AR) splice variant
Graham49
in
Advanced Prostate Cancer
2 months ago
Confirming blood tests needed to diagnose hyperthyroid (asking for my sister-in-law)
My sister-in-law told me that she recently was having trouble with excessive sweating... like, have to go home and change a drenched shirt kind of sweating. So as she said it in her words - She went to the general practitioner doctor, they did blood tests, and the numbers were low and so he's referring
My sister-in-law told me that she recently was having trouble with excessive sweating... like, have to go home and change a drenched shirt kind of sweating. So as she said it in her words - She went to the general practitioner doctor, they did blood tests, and the numbers were low and so he's referring
FallingInReverse
in
Thyroid UK
7 months ago
iron transfusion
Hi I’m just wondering how long people in the uk have waited for an iron infusion. I requested an iron infusion months and months ago as I can’t tolerate iron orally. Unfortunately my doctor forgot to put me on the waiting list and only amended that about a month ago after I mentioning that I was waiting
Hi I’m just wondering how long people in the uk have waited for an iron infusion. I requested an iron infusion months and months ago as I can’t tolerate iron orally. Unfortunately my doctor forgot to put me on the waiting list and only amended that about a month ago after I mentioning that I was waiting
Heather-rose
in
Restless Legs Syndrome
7 months ago
Vitamin/supplements
Can I ask what vitamins would be useful to try to support healthy thyroid function. I know iron, and vitamin B12 are important, I wondered if a specific Thyriod supplement was useful. I found this one, does anyone else take this? https://heynutrition.com/products/thyroid-complex?_gl=1*1d25mkn*_gcl_aw
Can I ask what vitamins would be useful to try to support healthy thyroid function. I know iron, and vitamin B12 are important, I wondered if a specific Thyriod supplement was useful. I found this one, does anyone else take this? https://heynutrition.com/products/thyroid-complex?_gl=1*1d25mkn*_gcl_aw
Fee52
in
Thyroid UK
7 months ago
Iron tablets - difference?
I’m based in the UK and am currently taking Ferrous Fumerate (switched from Ferrous Sulphate) to try to increase ferritin levels. My Ferritin levels had gone up and now seem to have dropped a little for some reason - new tests being done soon. I don’t know if this Ferrous Bisglycinate is available
I’m based in the UK and am currently taking Ferrous Fumerate (switched from Ferrous Sulphate) to try to increase ferritin levels. My Ferritin levels had gone up and now seem to have dropped a little for some reason - new tests being done soon. I don’t know if this Ferrous Bisglycinate is available
Bowie4eva
in
Restless Legs Syndrome
7 months ago
Oral iron regimen
I had an iron infusion (Newcastle uk) last December which put my serum ferritin up from 37 to 237, and helped considerably. However, it has gradually slipped back to 180, so I am hoping to start the oral gentle iron. Please can someone remind me of the best time to take these, and dosage. The tablets
I had an iron infusion (Newcastle uk) last December which put my serum ferritin up from 37 to 237, and helped considerably. However, it has gradually slipped back to 180, so I am hoping to start the oral gentle iron. Please can someone remind me of the best time to take these, and dosage. The tablets
Edengirl58
in
Restless Legs Syndrome
7 months ago
D day is here!
after a year of enduring this tumour, D Day is here! Surgery is just hours away. feeling good. After being left quite ill after a failed iron infusion, but made better by one which worked with a blood transfusion, feeling good. Thats not to say that there arent butterflies, of course there are. But
after a year of enduring this tumour, D Day is here! Surgery is just hours away. feeling good. After being left quite ill after a failed iron infusion, but made better by one which worked with a blood transfusion, feeling good. Thats not to say that there arent butterflies, of course there are. But
Hidden
Community Ambassador
in
Changing Faces
7 months ago
The most common failures in relation to the treatment of RLS, from my experience:
My name is Kimberley Bradfield and I am a clinical negligence solicitor at Switalskis Solicitors. Switalskis is a large firm that specialises in clinical negligence and has offices across the UK. We have successfully settled a number of clinical negligence cases relating to the negligent treatment of
My name is Kimberley Bradfield and I am a clinical negligence solicitor at Switalskis Solicitors. Switalskis is a large firm that specialises in clinical negligence and has offices across the UK. We have successfully settled a number of clinical negligence cases relating to the negligent treatment of
Switalskis
in
Restless Legs Syndrome
4 months ago
High TPO antibodies.
My TPO antibody levels have been consistently high around 500 since 2016, tested annually. My TSH and T4 levels are within range requiring no treatment; TSH at 2.51 and T4 15.7. They have also been at similar levels since 2016 tested annually. My GP states that the antibodies cannot be attacking my
My TPO antibody levels have been consistently high around 500 since 2016, tested annually. My TSH and T4 levels are within range requiring no treatment; TSH at 2.51 and T4 15.7. They have also been at similar levels since 2016 tested annually. My GP states that the antibodies cannot be attacking my
Fee52
in
Thyroid UK
8 months ago
Pramipexole, Mirtazapine and RLS
Hi,I suffered from RLS for 12yrs, but never took any medications. Earlier this year after discovering I had ferritin of 18, a short course of iron supplements increasing my ferritin to 55 resolved all RLS symptoms. A few weeks ago I unfortunately developed insomnia due to anxiety and GP commenced Mirtazapine
Hi,I suffered from RLS for 12yrs, but never took any medications. Earlier this year after discovering I had ferritin of 18, a short course of iron supplements increasing my ferritin to 55 resolved all RLS symptoms. A few weeks ago I unfortunately developed insomnia due to anxiety and GP commenced Mirtazapine
Purdy_123
in
Restless Legs Syndrome
8 months ago
Iron test results advise please!
Hi, Thanks for the great advice on my last post. Latest Thyroid results: TSH 0.824 (0.27 - 4.2) FT3 4.2 (3.1 - 6.8) FT4 15.2 (12 -22) TPA antibodies 13.1 (0 -34) Thyroglobulin antibodies 285 (0 -115) HIGH Since my last post I have seen a private thyroid GP and have been prescribed T3 I took
Hi, Thanks for the great advice on my last post. Latest Thyroid results: TSH 0.824 (0.27 - 4.2) FT3 4.2 (3.1 - 6.8) FT4 15.2 (12 -22) TPA antibodies 13.1 (0 -34) Thyroglobulin antibodies 285 (0 -115) HIGH Since my last post I have seen a private thyroid GP and have been prescribed T3 I took
Bluecat77
in
Thyroid UK
8 months ago
PV - Folic Acid and Vit D
Hi Please excuse if this has been asked before, I’m sure it has but can’t find the post 😬 I have PV and had blood done at Dr recently and was told I needed to take folic acid and Vit D. I take HU which has recently been reduced by 1 tablet a week and last bloods were HCT 38, Hb 13.4, WBC 7.6
Hi Please excuse if this has been asked before, I’m sure it has but can’t find the post 😬 I have PV and had blood done at Dr recently and was told I needed to take folic acid and Vit D. I take HU which has recently been reduced by 1 tablet a week and last bloods were HCT 38, Hb 13.4, WBC 7.6
Hocus58
in
MPN Voice
8 months ago
Iron - test results - advice please
Hi - In a nutshell I'm hypothyroid with a lot of stomach issues - gastritis amongst other things - plus poor converter (I have the dud deiodinase enzyme - test done privately) I mentioned to the GP that I also get a bit out of breath - when I read about 'air hunger' on here it really struck a chord.
Hi - In a nutshell I'm hypothyroid with a lot of stomach issues - gastritis amongst other things - plus poor converter (I have the dud deiodinase enzyme - test done privately) I mentioned to the GP that I also get a bit out of breath - when I read about 'air hunger' on here it really struck a chord.
Rambling9
in
Thyroid UK
8 months ago
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