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AI and prostate cancer, early days, but interesting
https://www.medindia.net/news/ai-reveals-subtypes-in-prostate-cancer-enhancing-treatment-215102-1.htm Apparently AI has helped analyze PCa from micro and macro evolutionary perspective and identified two sub types. "Our research demonstrates that prostate tumors evolve along multiple pathways, leading
https://www.medindia.net/news/ai-reveals-subtypes-in-prostate-cancer-enhancing-treatment-215102-1.htm Apparently AI has helped analyze PCa from micro and macro evolutionary perspective and identified two sub types. "Our research demonstrates that prostate tumors evolve along multiple pathways, leading
FRTHBST
in
Prostate Cancer Network
5 months ago
PSA back up after radiation
After 4 .5 weeks of radiation PSA dropped from 6.6 to 3.46 but on 6/3 went up to 5.88. I have MO appt 6/11 and he has previously indicated that docetaxel could be the next step. Following last PSA increase switched from Zytiga to Xtandi. I am guessing that a PET scan is in order and maybe SBRT prior
After 4 .5 weeks of radiation PSA dropped from 6.6 to 3.46 but on 6/3 went up to 5.88. I have MO appt 6/11 and he has previously indicated that docetaxel could be the next step. Following last PSA increase switched from Zytiga to Xtandi. I am guessing that a PET scan is in order and maybe SBRT prior
alperk
in
Advanced Prostate Cancer
1 month ago
What AI should i be using for my cancer research
I constantly am searching articles on prostate cancer and it is so easy to go off on infinite tangents and never come up with a clear plan. I see AI is very helpful and I see it as taking a big part in the future of fighting this beast. Any suggestions on which AI to utilize for this adventure?
I constantly am searching articles on prostate cancer and it is so easy to go off on infinite tangents and never come up with a clear plan. I see AI is very helpful and I see it as taking a big part in the future of fighting this beast. Any suggestions on which AI to utilize for this adventure?
KocoPr
in
Advanced Prostate Cancer
5 months ago
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Provenge immunotherapy
After 5.5 years on Lupron (no Zytiga, Xtandi, Daro, etc.), my PSA hit its highest points ever (1.92), although I'm still not 2 points above my lowest reading of 0.5 (only one of those). I'm metastatic and was at diagnosis, so still have prostate. I've been researching Provenge a bit, and understand that
After 5.5 years on Lupron (no Zytiga, Xtandi, Daro, etc.), my PSA hit its highest points ever (1.92), although I'm still not 2 points above my lowest reading of 0.5 (only one of those). I'm metastatic and was at diagnosis, so still have prostate. I've been researching Provenge a bit, and understand that
dhccpa
in
Advanced Prostate Cancer
1 month ago
Examining Prostate Cancer Survival Outcomes by Patient Age and Treatment Type in Patients with mHSPC
“the research suggests a differential impact between androgen receptor antagonists (like enzalutamide, apalutamide, and darolutamide) and androgen synthesis inhibitors (such as abiraterone), with antagonists showing a more pronounced benefit” https://www.urotoday.com/video-lectures/asco-gu-2024/video
“the research suggests a differential impact between androgen receptor antagonists (like enzalutamide, apalutamide, and darolutamide) and androgen synthesis inhibitors (such as abiraterone), with antagonists showing a more pronounced benefit” https://www.urotoday.com/video-lectures/asco-gu-2024/video
Maxone73
in
Advanced Prostate Cancer
5 months ago
Prostap query
Hi I'm on my 4th prostap injection under a proper endo clinic now, i was on zoladex.Is it normal to get breakthrough bleeding and pain the week before my next injection is due?
Hi I'm on my 4th prostap injection under a proper endo clinic now, i was on zoladex.Is it normal to get breakthrough bleeding and pain the week before my next injection is due?
Lilian75
in
Endometriosis UK
9 months ago
Just some new Information about AI
Came across this article a couple days ago. https://www.news-medical.net/news/20210924/Researchers-identify-two-subtypes-of-metastatic-prostate-cancer.aspx#:~:text=Building%20off%20of%20earlier%20studies%20that%20discovered%20clinically,into%20two%20types%20known%20as%20luminal%20and%20basal AI has
Came across this article a couple days ago. https://www.news-medical.net/news/20210924/Researchers-identify-two-subtypes-of-metastatic-prostate-cancer.aspx#:~:text=Building%20off%20of%20earlier%20studies%20that%20discovered%20clinically,into%20two%20types%20known%20as%20luminal%20and%20basal AI has
chefjlu
in
Advanced Prostate Cancer
5 months ago
Pluvicto
My dad had his 1st pluvicto injection beginning of May He had his PSA taken 3 weeks later. It went from 16 to 23. I’m hoping this isn’t an indicator that this will fail too. He has been dealing with prostate cancer for 20+ years -prostate removed - watching till number doubled - maybe 5 years
My dad had his 1st pluvicto injection beginning of May He had his PSA taken 3 weeks later. It went from 16 to 23. I’m hoping this isn’t an indicator that this will fail too. He has been dealing with prostate cancer for 20+ years -prostate removed - watching till number doubled - maybe 5 years
Jshaw916
in
Advanced Prostate Cancer
2 months ago
Reminder to Subscribe to our Prostate Cancer Community Newsletter
Please don't forget to subscribe to our community newsletter. It's free and helpful. Click here: https://malecare.org/prostate-cancer-newsletter/
Please don't forget to subscribe to our community newsletter. It's free and helpful. Click here: https://malecare.org/prostate-cancer-newsletter/
Darryl
Partner
in
Advanced Prostate Cancer
5 months ago
PSA rockets up to 344
Hello - I received quite shocking news during my visit to the Mayo Clinic last week. My PSA has jumped to 344 from a low of 3.6 last November, when I completed chemo with cabazitaxel. PSA did start to rise quite soon, into double digits, but this is by far my highest PSA ever. Dr. Kwon recommended
Hello - I received quite shocking news during my visit to the Mayo Clinic last week. My PSA has jumped to 344 from a low of 3.6 last November, when I completed chemo with cabazitaxel. PSA did start to rise quite soon, into double digits, but this is by far my highest PSA ever. Dr. Kwon recommended
Arcticfox44
in
Advanced Prostate Cancer
2 months ago
PSA-Nadir vs Testosterone-Nadir comparing Non-CRPC to CRPX men
These plots show the linear relationship between median PSA-Nadir and median Testosterone-Nadir, pointing towards the Origin (i.e., 0 PSA-Nadir at 0 T-Nadir.). N= 38 men. The upper to graphs compare median PSA-nadir and median T-Nadir for Non-CRPC and CPRC groups (CPRC = Castrate Resistant Prostate
These plots show the linear relationship between median PSA-Nadir and median Testosterone-Nadir, pointing towards the Origin (i.e., 0 PSA-Nadir at 0 T-Nadir.). N= 38 men. The upper to graphs compare median PSA-nadir and median T-Nadir for Non-CRPC and CPRC groups (CPRC = Castrate Resistant Prostate
janebob99
in
Advanced Prostate Cancer
5 months ago
Kishan's 6 month Androgen Annihilation Therapy Study for metastatic PCa
https://x.com/prostatecell/status/1770206641813696808?s=46 https://bit.ly/43rr68x seems to be a promising tactic for oligometastatic PCa, that combines SBRT with an ADT mix . The Abstract starts off by noting that with metastatic hormone sensitive PCa, recurrence almost always happens within six months
https://x.com/prostatecell/status/1770206641813696808?s=46 https://bit.ly/43rr68x seems to be a promising tactic for oligometastatic PCa, that combines SBRT with an ADT mix . The Abstract starts off by noting that with metastatic hormone sensitive PCa, recurrence almost always happens within six months
Xavier10
in
Advanced Prostate Cancer
2 months ago
Could This Alternative Regiment Be Decelerating My PSA?
Between Summer of 2021 and Summer of 2023--two solid years--my PSA went from 11.5 to 15.3, roughly two points per year. Having concern about my PSA, I ventured into a more "aggressive anti-prostate cancer diet," centered around legumes/black, purple, wild rices/walnuts/flaxseed/tomato paste
Between Summer of 2021 and Summer of 2023--two solid years--my PSA went from 11.5 to 15.3, roughly two points per year. Having concern about my PSA, I ventured into a more "aggressive anti-prostate cancer diet," centered around legumes/black, purple, wild rices/walnuts/flaxseed/tomato paste
back2health
in
Advanced Prostate Cancer
2 months ago
Best alternative PET for PSMA negative PCa
Asking for a friend. He was diagnosed 3 years ago with high risk high volume (Gleason 3+5) PCa. Treated with EBRT + LDRBT + ADT (18 months). His PSA was undetectable but is now rising (3+) but PSMA-PET was negative, even in the prostate - implying PSMA non-avid cancer. What would be the best non-PSMA
Asking for a friend. He was diagnosed 3 years ago with high risk high volume (Gleason 3+5) PCa. Treated with EBRT + LDRBT + ADT (18 months). His PSA was undetectable but is now rising (3+) but PSMA-PET was negative, even in the prostate - implying PSMA non-avid cancer. What would be the best non-PSMA
Vynbal
in
Advanced Prostate Cancer
2 months ago
Do testosterone supplements help raise testosterone levels after use of Lupron with radiation?
trying to decide to decide between surgery and radiation w/Lupron as a treatment for prostate cancer. I’m particularly concerned with how long it takes to restore testerone levels after 6 months on Lupron. Does the use of testerone supplements help restore T levels more quickly?
trying to decide to decide between surgery and radiation w/Lupron as a treatment for prostate cancer. I’m particularly concerned with how long it takes to restore testerone levels after 6 months on Lupron. Does the use of testerone supplements help restore T levels more quickly?
Godfather2
in
Prostate Cancer Network
5 months ago
ADT failure
We saw my Dad's MO on 5/23. Over the course of 4 weeks my dad's PSA moved from 1.46 to 2.14, He said we need to be on Zytiga for three months before we can deem it a failure, but just like Xtandi, it appears my dad had limited help with it. We have talked about the next steps, chemo and pluvicto. My
We saw my Dad's MO on 5/23. Over the course of 4 weeks my dad's PSA moved from 1.46 to 2.14, He said we need to be on Zytiga for three months before we can deem it a failure, but just like Xtandi, it appears my dad had limited help with it. We have talked about the next steps, chemo and pluvicto. My
lgutman
in
Advanced Prostate Cancer
2 months ago
Post menopause, pernicious anaemia and endometriosis
Diagnosed with endomeriosis over 15 years years ago, had Prostap injections for 6 months, with little success and opted to try Mirena Coil first before hysterectomy. Mirena was a god send for me, it was great at controlling my symptons, I've had 3 mirena coils in total. The first one for a year
Diagnosed with endomeriosis over 15 years years ago, had Prostap injections for 6 months, with little success and opted to try Mirena Coil first before hysterectomy. Mirena was a god send for me, it was great at controlling my symptons, I've had 3 mirena coils in total. The first one for a year
Fiestadrive
in
Endometriosis UK
9 months ago
Interesting paper/discovery - two types of PCa
Found by AI: https://medicalxpress.com/news/2024-02-ai-reveals-prostate-cancer-disease.html [i]Artificial Intelligence has helped scientists reveal a new form of aggressive prostate cancer that could revolutionize how the disease is diagnosed and treated in the future.[/i] [i]The study published in
Found by AI: https://medicalxpress.com/news/2024-02-ai-reveals-prostate-cancer-disease.html [i]Artificial Intelligence has helped scientists reveal a new form of aggressive prostate cancer that could revolutionize how the disease is diagnosed and treated in the future.[/i] [i]The study published in
Don_1213
in
Prostate Cancer Network
5 months ago
Gummie relief for degarelix shots?
DH has so much pain with each monthly shot and can't take nsaids. Is there anything that won't make him loopy to use after shots for a few days? He is ready to go back to lupron, it hurts so much. Mail order preferred.Thanks!
DH has so much pain with each monthly shot and can't take nsaids. Is there anything that won't make him loopy to use after shots for a few days? He is ready to go back to lupron, it hurts so much. Mail order preferred.Thanks!
Chipnick
in
Advanced Prostate Cancer
5 months ago
Time to adjust my course, any suggestions?
Psa is on a steady increase again. I was taking extandi for a year up until 11 /23 over that yr my Psa had dropped from 29, 11/22 to 1.4 ,11/23. I was having significant SEs, brain fog mainly so I decided to switch to nubeqa (daralutimide) even tho there was a steady drop in PSA on extandi. Nubeqa
Psa is on a steady increase again. I was taking extandi for a year up until 11 /23 over that yr my Psa had dropped from 29, 11/22 to 1.4 ,11/23. I was having significant SEs, brain fog mainly so I decided to switch to nubeqa (daralutimide) even tho there was a steady drop in PSA on extandi. Nubeqa
rick8637
in
Advanced Prostate Cancer
2 months ago
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