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Before Fireworks and BallDrops, Where ever you live, please read this now.
Please make your year-end secure donation in any currency to Malecare now at https://malecare.org/donate Malecare is more than our massive and active online, Zoom, and in-person support groups. We're one of the world's most productive patient advocacy research groups, with several university and
Please make your year-end secure donation in any currency to Malecare now at https://malecare.org/donate Malecare is more than our massive and active online, Zoom, and in-person support groups. We're one of the world's most productive patient advocacy research groups, with several university and
Darryl
Partner
in
Advanced Prostate Cancer
7 months ago
Before Fireworks and BallDrops, Where ever you live, please read this
Please make your year-end secure donation in any currency to Malecare now at https://malecare.org/donate Malecare is more than our massive and active online, Zoom, and in-person support groups. We're one of the world's most productive patient advocacy research groups, with several university and
Please make your year-end secure donation in any currency to Malecare now at https://malecare.org/donate Malecare is more than our massive and active online, Zoom, and in-person support groups. We're one of the world's most productive patient advocacy research groups, with several university and
Darryl
Partner
in
Active Surveillance - Prostate Cancer
7 months ago
Promising! A review on selenium and gold nanoparticles combined photodynamic and photothermal prostate cancer tumors ablation
Check also the ongoing clinical trials. This seems very promising as it's extremely precise in delivering the payload and has got very little side effects. https://link.springer.com/article/10.1186/s11671-023-03936-z
Check also the ongoing clinical trials. This seems very promising as it's extremely precise in delivering the payload and has got very little side effects. https://link.springer.com/article/10.1186/s11671-023-03936-z
Maxone73
in
Advanced Prostate Cancer
7 months ago
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HIFU 2023 article does not seem positive
This article from early 2023 does not seem positive on HIFU. https://link.springer.com/article/10.1007/s00345-023-04352-9 I have a friend looking at HIFU in the setting of a clinical trial. He's Gleason 6 with just 1 of 12 portions of his prostate affected. Technically, he could do active surveillance
This article from early 2023 does not seem positive on HIFU. https://link.springer.com/article/10.1007/s00345-023-04352-9 I have a friend looking at HIFU in the setting of a clinical trial. He's Gleason 6 with just 1 of 12 portions of his prostate affected. Technically, he could do active surveillance
A0007720
in
Prostate Cancer Network
7 months ago
Clinical trial NCT05898399: for BRCA (ATM as well I suppose) mutations
Study of ART6043 in Advanced/Metastatic Solid Tumors Patients This company is also developing an interesting ATR inhibitor for ATM mutations https://classic.clinicaltrials.gov/ct2/show/NCT05898399
Study of ART6043 in Advanced/Metastatic Solid Tumors Patients This company is also developing an interesting ATR inhibitor for ATM mutations https://classic.clinicaltrials.gov/ct2/show/NCT05898399
Maxone73
in
Advanced Prostate Cancer
7 months ago
Is this a type of BAT treatment? Clinical trial
https://clinicaltrials.gov/study/NCT04363164?cond=prostate%20cancer&aggFilters=ages:older,funderType:industry%20fed%20nih%20other,phase:2%203%204,sex:m,status:rec,studyType:int&lat=44.6689341&lng=-93.3993751&locStr=Shakopee,%20MN%2055372&distance=130&page=3&rank=22#participation-criteria Not asking
https://clinicaltrials.gov/study/NCT04363164?cond=prostate%20cancer&aggFilters=ages:older,funderType:industry%20fed%20nih%20other,phase:2%203%204,sex:m,status:rec,studyType:int&lat=44.6689341&lng=-93.3993751&locStr=Shakopee,%20MN%2055372&distance=130&page=3&rank=22#participation-criteria Not asking
swwags
in
Advanced Prostate Cancer
7 months ago
clinical trials
have had all symptoms of pancreatitis from alcohol I think I have had every scan for the last 26 months since intial attack even EUS they say no chronic not even the subtle changes but elastase was 220 low normal ! I’m know something happen an they say everything is fine !! I’m trying to see what I
have had all symptoms of pancreatitis from alcohol I think I have had every scan for the last 26 months since intial attack even EUS they say no chronic not even the subtle changes but elastase was 220 low normal ! I’m know something happen an they say everything is fine !! I’m trying to see what I
Taper710
in
Chronic Pancreatitis Support
7 months ago
Platinum resistant - paclitaxel planned
Hi everyone,I am on my 3rd recurrence since treatment started in 2021. I'm stage 4 and now platinum resistant. Dr is starting me o n Paclitaxel 1xweek for 3 weeks followed by one week break for 6 months. There is a new clinical trial starting in my health area which wil potentiallyl be available for
Hi everyone,I am on my 3rd recurrence since treatment started in 2021. I'm stage 4 and now platinum resistant. Dr is starting me o n Paclitaxel 1xweek for 3 weeks followed by one week break for 6 months. There is a new clinical trial starting in my health area which wil potentiallyl be available for
COHEN123
in
My Ovacome
7 months ago
I would love to see a Clinical Trial on TTFD
I gave up on TTFD (thiamine tetrahydrofurfuryl disulfide - a B1 derivative) because; I would settle in on a sweet-spot, within a few weeks I would overdose, I lowered my dose and repeated again & again. Thinking maybe that wouldn’t be a bad thing — could it be a cure and would I get down to just recommended
I gave up on TTFD (thiamine tetrahydrofurfuryl disulfide - a B1 derivative) because; I would settle in on a sweet-spot, within a few weeks I would overdose, I lowered my dose and repeated again & again. Thinking maybe that wouldn’t be a bad thing — could it be a cure and would I get down to just recommended
Gcf51
in
Cure Parkinson's
7 months ago
Embark Phase 3 clinical trial
Came across this today --- https://www.health.harvard.edu/blog/after-prostate-cancer-treatment-a-new-standard-of-care-for-rising-psa-202312203001
Came across this today --- https://www.health.harvard.edu/blog/after-prostate-cancer-treatment-a-new-standard-of-care-for-rising-psa-202312203001
chefjlu
in
Advanced Prostate Cancer
7 months ago
Finally!
Back in July I had a response to a FOI, which I challenged. I sent out numerous emails to different NHS governing bodies. I met a brick wall. Today an email turned up out of the blue from my Health Board. It only took them five months. The complaint was that the blood testing for thyroid did not
Back in July I had a response to a FOI, which I challenged. I sent out numerous emails to different NHS governing bodies. I met a brick wall. Today an email turned up out of the blue from my Health Board. It only took them five months. The complaint was that the blood testing for thyroid did not
serenfach
in
Thyroid UK
7 months ago
Hormones and Aging: An Endocrine Society Scientific Statement" was presented at ENDO 2023
I haven't read it yet, but thought this looks interesting. A Medscape article titled 'A 'One-Stop Shop': New Guidance on Hormones and Aging' stated: 'A new statement from The Endocrine Society on hormones and aging highlights the differences between normal aging and disease, and when treatment is
I haven't read it yet, but thought this looks interesting. A Medscape article titled 'A 'One-Stop Shop': New Guidance on Hormones and Aging' stated: 'A new statement from The Endocrine Society on hormones and aging highlights the differences between normal aging and disease, and when treatment is
BB001
in
Thyroid UK
7 months ago
Drug fails in Phase II trial for treating Parkinson's Disease - Exenatide (Byetta, Bydureon)
Evidence suggest that microglia are relevant to Parkinson's disease pathogenesis, therefore the recent clinical trial warranted exploration of trying to attenuate pathogenic microglial function. They sought to test the safety and efficacy of NLY01—a brain penetrant, pegylated, longer-lasting version
Evidence suggest that microglia are relevant to Parkinson's disease pathogenesis, therefore the recent clinical trial warranted exploration of trying to attenuate pathogenic microglial function. They sought to test the safety and efficacy of NLY01—a brain penetrant, pegylated, longer-lasting version
Baron1
in
Cure Parkinson's
7 months ago
Start of SCT journey
Quick recap for those that haven't followed my previous posts. Diagnosed September 2022 with primary MF, no previous signs or symptoms before catching Covid in June 2022 and health deteriorating until GP visit at end of August 2022. After some RBC transfusions, blood tests and BMP I enrolled on FEDORA
Quick recap for those that haven't followed my previous posts. Diagnosed September 2022 with primary MF, no previous signs or symptoms before catching Covid in June 2022 and health deteriorating until GP visit at end of August 2022. After some RBC transfusions, blood tests and BMP I enrolled on FEDORA
Flyingsteamer
in
MPN Voice
7 months ago
Vitamin D: Secondary Analysis of the VITAL Randomized Clinical Trial (with a surprise!)
I don't know if this was previously posted (it's from 2020)...but it's fascinating. In their first analysis the researchers did not take into consideration...fat https://pubmed.ncbi.nlm.nih.gov/33206192/ Ah the secondary analysis was done by the same researchers from the original study!
I don't know if this was previously posted (it's from 2020)...but it's fascinating. In their first analysis the researchers did not take into consideration...fat https://pubmed.ncbi.nlm.nih.gov/33206192/ Ah the secondary analysis was done by the same researchers from the original study!
Maxone73
in
Advanced Prostate Cancer
7 months ago
Not about advanced PCa, but might be useful: curcumin and BPH
The nano-micellar curcumin improves International Prostate Symptoms Score (IPSS) in patients with benign prostatic hyperplasia: a randomized clinical trial https://pubmed.ncbi.nlm.nih.gov/37458774/
The nano-micellar curcumin improves International Prostate Symptoms Score (IPSS) in patients with benign prostatic hyperplasia: a randomized clinical trial https://pubmed.ncbi.nlm.nih.gov/37458774/
Maxone73
in
Advanced Prostate Cancer
7 months ago
hu CAR-T 19 IL-18 4th Generation Clinical Trial 90 Day Check-up With All of My Favorite Tests
It's been a long time since I have received a MRD negative diagnosis, 13 years to be exact, after my FCR treatment. All of the other treatments didn't require a BMB to confirm a negative reading, I had a few remissions, but they were just on paper. My blood counts were good, and I felt fine, but a relapse
It's been a long time since I have received a MRD negative diagnosis, 13 years to be exact, after my FCR treatment. All of the other treatments didn't require a BMB to confirm a negative reading, I had a few remissions, but they were just on paper. My blood counts were good, and I felt fine, but a relapse
steve5441
in
CLL Support
7 months ago
Not about PCa, but worth checking...CRISPR in oncology phase 1-2
"A clinical trial to assess the safety and efficacy of genetically-engineered, neoantigen-specific Tumor Infiltrating Lymphocytes (TIL) in which the intracellular immune checkpoint CISH has been inhibited using CRISPR gene editing for the treatment of Gastro-Intestinal (GI) Cancer." https://www.clinicaltrials.gov
"A clinical trial to assess the safety and efficacy of genetically-engineered, neoantigen-specific Tumor Infiltrating Lymphocytes (TIL) in which the intracellular immune checkpoint CISH has been inhibited using CRISPR gene editing for the treatment of Gastro-Intestinal (GI) Cancer." https://www.clinicaltrials.gov
Maxone73
in
Advanced Prostate Cancer
7 months ago
Wait or start docetaxel?
Currently taking Nubeqa and Orgovyx but PSA doubling time is only 7 weeks and PSMA scan shows activity in abdominal lymph nodes, 2 vertebrae and 2 ribs. MO suggested DORA Clinical trial (everyone gets docetaxel, half get radium) but the head of a trial I was previously in at NIH feels that unless a CT
Currently taking Nubeqa and Orgovyx but PSA doubling time is only 7 weeks and PSMA scan shows activity in abdominal lymph nodes, 2 vertebrae and 2 ribs. MO suggested DORA Clinical trial (everyone gets docetaxel, half get radium) but the head of a trial I was previously in at NIH feels that unless a CT
AllenMarco
in
Advanced Prostate Cancer
7 months ago
Clinical trial: keep an eye on this
First results should be available by the first months of 2024. Radiation Medication (Radium-223 Dichloride) Versus Radium-223 Dichloride Plus Radiation Enhancing Medication (M3814) Versus Radium-223 Dichloride Plus M3814 Plus Avelumab (a Type of Immunotherapy) for Advanced Prostate Cancer Not Responsive
First results should be available by the first months of 2024. Radiation Medication (Radium-223 Dichloride) Versus Radium-223 Dichloride Plus Radiation Enhancing Medication (M3814) Versus Radium-223 Dichloride Plus M3814 Plus Avelumab (a Type of Immunotherapy) for Advanced Prostate Cancer Not Responsive
Maxone73
in
Advanced Prostate Cancer
7 months ago
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