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Researchers add to existing evidence that vitamin B3 may help slow down the progression of Parkinson'
https://www.parkinsons.org.uk/news/more-research-shows-potential-benefits-vitamin-b3-parkinsons A new phase 1 clinical trial, the NR-SAFE study, has published promising signs that taking a high dose of vitamin B3 is safe, and can reduce some symptoms for people with Parkinson’s.
https://www.parkinsons.org.uk/news/more-research-shows-potential-benefits-vitamin-b3-parkinsons A new phase 1 clinical trial, the NR-SAFE study, has published promising signs that taking a high dose of vitamin B3 is safe, and can reduce some symptoms for people with Parkinson’s.
CuriousMe12
in
Cure Parkinson's
7 months ago
Cancer causation -- inflammation and statistics
https://www.newyorker.com/magazine/2023/12/18/all-the-carcinogens-we-cannot-see Those of us whose cancer is quiet don't want to wake it up, but nobody knows for sure what to do (or not do). This article provides some food for thought and offers the opportunity for us to revisit our views about the
https://www.newyorker.com/magazine/2023/12/18/all-the-carcinogens-we-cannot-see Those of us whose cancer is quiet don't want to wake it up, but nobody knows for sure what to do (or not do). This article provides some food for thought and offers the opportunity for us to revisit our views about the
mistersafety
in
Advanced Prostate Cancer
7 months ago
Restless Leg Syndrome, neuromodulation..
Treatment was well tolerated, and no adverse events were reported. Our case series shows a potential role for self-administered taVNS in patients with severe pharmacoresistant RLS. Hartley S, Bao G, Russo A, Zagdoun M, Chevallier S, Lofaso F, Leotard A, Azabou E. Self-administered non-invasive vagus
Treatment was well tolerated, and no adverse events were reported. Our case series shows a potential role for self-administered taVNS in patients with severe pharmacoresistant RLS. Hartley S, Bao G, Russo A, Zagdoun M, Chevallier S, Lofaso F, Leotard A, Azabou E. Self-administered non-invasive vagus
House2
in
Restless Legs Syndrome
7 months ago
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Old new approach! MYC inhibitors
myc is a gene present in most kinds of cancer, something has reached clinical trials at last! https://www.peptomyc.com/results-revealed-from-phase-i-clinical-trial-of-the-first-drug-to-successfully-inhibit-the-myc-gene-which-drives-many-common-cancers/
myc is a gene present in most kinds of cancer, something has reached clinical trials at last! https://www.peptomyc.com/results-revealed-from-phase-i-clinical-trial-of-the-first-drug-to-successfully-inhibit-the-myc-gene-which-drives-many-common-cancers/
Maxone73
in
Advanced Prostate Cancer
7 months ago
Advances in solid tumors: finnish clinical trial
Interesting results are coming! Bexmarilimab seems to be able to improve immunotherapy. It was not yet tested on prostate cancer, but it's already commercially used to treat blood malignacies. As single agent: https://www.faron.com/our-science/clinical-trials/matins "Latest data showed a three-fold
Interesting results are coming! Bexmarilimab seems to be able to improve immunotherapy. It was not yet tested on prostate cancer, but it's already commercially used to treat blood malignacies. As single agent: https://www.faron.com/our-science/clinical-trials/matins "Latest data showed a three-fold
Maxone73
in
Advanced Prostate Cancer
7 months ago
Need to Change Treatment
So I have progression after two years on Ibrance and Letrozole. I have an opportunity to participate in a clinical trial in my town in which I would be randomly assigned to Giredestrant, a promising oral SERD (monotherapy) or both Giredestrant with a new Pikc3a drug. My standard of care option would
So I have progression after two years on Ibrance and Letrozole. I have an opportunity to participate in a clinical trial in my town in which I would be randomly assigned to Giredestrant, a promising oral SERD (monotherapy) or both Giredestrant with a new Pikc3a drug. My standard of care option would
Trissh
in
SHARE Metastatic Breast Cancer
7 months ago
Intense jaw pain (pt.2)
Three months ago my husband developed intense right jaw pain. After multiple scans showing "something" (thankfully no PSMA activity) he had a surgical bone biopsy 11/29. Two days ago we received the pathology report but have not been able to speak with the Dr. to help us understand it. The good news
Three months ago my husband developed intense right jaw pain. After multiple scans showing "something" (thankfully no PSMA activity) he had a surgical bone biopsy 11/29. Two days ago we received the pathology report but have not been able to speak with the Dr. to help us understand it. The good news
Decktime
in
Advanced Prostate Cancer
7 months ago
ST-067 in combination with pembrolizumab clinical trial
https://www.moffitt.org/clinical-trials-and-studies/clinical-trial-21340/
https://www.moffitt.org/clinical-trials-and-studies/clinical-trial-21340/
Maxone73
in
Advanced Prostate Cancer
7 months ago
Anyone can access this article?
"As Bertagnolli steps in, NIH and FDA reenvision clinical trials and evidence generation"..it could be the modernization of clinical trials I have been waiting for The only Monica Bertagnolli I knew was a tough girl, I want to see if this Monica is also such a tough cookie https://cancerletter.com
"As Bertagnolli steps in, NIH and FDA reenvision clinical trials and evidence generation"..it could be the modernization of clinical trials I have been waiting for The only Monica Bertagnolli I knew was a tough girl, I want to see if this Monica is also such a tough cookie https://cancerletter.com
Maxone73
in
Advanced Prostate Cancer
7 months ago
new clinical trial Risvodetinib (IkT-148009)
The 201 Clinical Trial For Patients With Untreated Parkinson’s Disease The 201 Clinical Trial is a trial that will explore whether a novel drug, Risvodetinib (IkT-148009), can slow or halt progression of Parkinson’s disease. The trial will also evaluate whether Risvodetinib (IkT-148009) can partially
The 201 Clinical Trial For Patients With Untreated Parkinson’s Disease The 201 Clinical Trial is a trial that will explore whether a novel drug, Risvodetinib (IkT-148009), can slow or halt progression of Parkinson’s disease. The trial will also evaluate whether Risvodetinib (IkT-148009) can partially
Boscoejean
in
Cure Parkinson's
7 months ago
first U.S. patients dosed in expanded Phase 1b clinical trial of CB307 for patients with mCRPC
one step at a time….immune therapy for prostate cancer is becoming hotter! https://finance.yahoo.com/news/crescendo-biologics-announces-first-u-120000112.html
one step at a time….immune therapy for prostate cancer is becoming hotter! https://finance.yahoo.com/news/crescendo-biologics-announces-first-u-120000112.html
Maxone73
in
Advanced Prostate Cancer
7 months ago
Vitamin D and Anemia: Insights into an Emerging Association
Found an interesting study. The conclusion sold it for me. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659411/ CONCLUSION Vitamin D is associated with anemia in various study populations and recent evidence suggests that the association may differ by race and is likely specific to anemia of inflammation
Found an interesting study. The conclusion sold it for me. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659411/ CONCLUSION Vitamin D is associated with anemia in various study populations and recent evidence suggests that the association may differ by race and is likely specific to anemia of inflammation
WideBody
in
Restless Legs Syndrome
7 months ago
New to this
I’m Jo, age 66, living in Chicago. I believe I have early stage PD. I haven’t been diagnosed yet have been acting out dreams for at least five years, and my right arm doesn’t swing. I’m hoping to get diagnosed soon so I can participate in a clinical trial.
I’m Jo, age 66, living in Chicago. I believe I have early stage PD. I haven’t been diagnosed yet have been acting out dreams for at least five years, and my right arm doesn’t swing. I’m hoping to get diagnosed soon so I can participate in a clinical trial.
Jomaxx
in
Cure Parkinson's
8 months ago
Provenge Complete
Well folks, I completed Provenge with no issues or SE’s to note. I understand my PSA will not be lowered by this treatment and it has gone way up, from 24 first of October to 58 last week. I am still waiting to hear from Sarah Cannon Research to review possible clinical trials. In a way I feel like
Well folks, I completed Provenge with no issues or SE’s to note. I understand my PSA will not be lowered by this treatment and it has gone way up, from 24 first of October to 58 last week. I am still waiting to hear from Sarah Cannon Research to review possible clinical trials. In a way I feel like
Pmann
in
Advanced Prostate Cancer
8 months ago
Doxorubicin pegylated liposomal
Hello Thrivers I hope you are all going well.I had a bone biopsy last week, I can honestly say it was a horrible experience. One I hope never to repeat. I have now been diagnosed with triple negative breast cancer. My first diagnoses was er+pr+ her 2 negative. Mets to bones and liver last September.
Hello Thrivers I hope you are all going well.I had a bone biopsy last week, I can honestly say it was a horrible experience. One I hope never to repeat. I have now been diagnosed with triple negative breast cancer. My first diagnoses was er+pr+ her 2 negative. Mets to bones and liver last September.
Cherry38
in
SHARE Metastatic Breast Cancer
8 months ago
BROQ/Prostaphane
Last week I had my 3 monthly PSA check and was happy and surprised to see that it had remained unchanged at 0.07. It had previously been creeping up and I am not currently on any treatement since my Cyberknife to a lymph node in December 21 together with 6 months of bicalutamide. I take a large variety
Last week I had my 3 monthly PSA check and was happy and surprised to see that it had remained unchanged at 0.07. It had previously been creeping up and I am not currently on any treatement since my Cyberknife to a lymph node in December 21 together with 6 months of bicalutamide. I take a large variety
GreenStreet
in
Fight Prostate Cancer
8 months ago
Richter's Transformation: standardized therapy or clinical trial
My father was diagnosed CLL 4 years ago and hasn't been treated. Recently he did a PET CT because of enlarged lmpth nodes and doctor said it's very possible he has Richter's Transformation. May I know if any one has same experience with Richters but not treated before? Could you share the treatment and
My father was diagnosed CLL 4 years ago and hasn't been treated. Recently he did a PET CT because of enlarged lmpth nodes and doctor said it's very possible he has Richter's Transformation. May I know if any one has same experience with Richters but not treated before? Could you share the treatment and
janeychen5712
in
CLL Support
8 months ago
Progressing nanotechnology to improve targeted cancer treatment: not related to prostate cancer only
The article emphasizes the challenges in transitioning from lab findings to clinical applications, stressing the need for further research to optimize nanocarriers for cancer therapy. It explores the potential of nanocarriers and compounds for selective tumor targeting, including liposomes, nanoparticles
The article emphasizes the challenges in transitioning from lab findings to clinical applications, stressing the need for further research to optimize nanocarriers for cancer therapy. It explores the potential of nanocarriers and compounds for selective tumor targeting, including liposomes, nanoparticles
Maxone73
in
Advanced Prostate Cancer
8 months ago
Psilocybin clinical trial
For people in both New York (NYU) and Colorado (CU Anschutz). Dont forget about the mental health side of fighting this dragon, whether traditional mental health services or something novel like this clinical trial. I’ve done traditional mental health (with anxiety meds) for a couple years now to help
For people in both New York (NYU) and Colorado (CU Anschutz). Dont forget about the mental health side of fighting this dragon, whether traditional mental health services or something novel like this clinical trial. I’ve done traditional mental health (with anxiety meds) for a couple years now to help
Chugach
in
Advanced Prostate Cancer
8 months ago
Hot off the press. Randomized, double-blind safety trial of high dose nicotinamide riboside in Parkinson’s disease.
Open access Published: 28 November 2023 Abstract Nicotinamide adenine dinucleotide (NAD) replenishment therapy using nicotinamide riboside (NR) shows promise for Parkinson’s disease (PD) and other neurodegenerative disorders. However, the optimal dose of NR remains unknown, and doses exceeding 2000
Open access Published: 28 November 2023 Abstract Nicotinamide adenine dinucleotide (NAD) replenishment therapy using nicotinamide riboside (NR) shows promise for Parkinson’s disease (PD) and other neurodegenerative disorders. However, the optimal dose of NR remains unknown, and doses exceeding 2000
SilentEchoes
in
Cure Parkinson's
8 months ago
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