Platinum resistant - paclitaxel planned

[COHEN123]

Hi everyone,I am on my 3rd recurrence since treatment started in 2021. I'm stage 4 and now platinum resistant. Dr is starting me o n Paclitaxel 1xweek for 3 weeks followed by one week break for 6 months. There is a new clinical trial starting in my health area which wil potentiallyl be available for me after this treatment if all goes well, though I don't know details .

I just wondered if anyone else had just had Paclitaxel and how it had gone.

Whatever else is happening in your lives I hope that you will be able to have a good aXmas

Sue

[Irisisme]

Hi COhen123/Sue,

Firstly, Merry Christmas 🤶🏻

I tried to get onto a trial at University College Hospital, London but my liver enzymes in blood were too high and they wouldn’t take me. The lead was Dr Rowen Miller and I later had a consultation with her.

I’m 5th line - just started Paclitaxel (which will probably rule me out for any future trials).

[Irisisme in reply to Irisisme]

Oops sorry- I didn’t finish it!!!!

Dr. Miller suggested Avastin every 3 weeks and as I’m UK I had Paclitaxel on NHS and I pay for Avastin. I last had Paclitaxel in 2021 and Avastin in 2017. Based on the pain level I think it’s working but I’ve only had a baseline scan so far, so nothing to go on to be certain.

Still early days for me too but it’s a last ditch option for me 🤞🤞. You’re on it now so 🤞🤞 for you too. I’m finding it incredibly painful - and I’ve been through a LOT of chemo drugs!

Good Luck for the New Year to come, who knows how things will go.

Iris -sending hugs 🤗 🤗

[Pooshon in reply to Irisisme]

Merry Christmas to you🎄🎅

I’ve just finished 6 months of weekly taxol and I was fine though the last 2 rounds did leave me tired.

I’ve just had my scan results showing stable disease so I’m feeling positive.

Where is the trial you mentioned? I don’t have any maintenance treatments.

Good luck and best wishes to you. ❤️

[COHEN123 in reply to Pooshon]

Merry Christmas to you too. Just had Christmas breakfast which is always a good thing!

thanks for sharing your experience and so pleasaed your results are stable . What a roller coaster we are on!

There is a trial starting in Felindre in cardiff in the New Year. I would have gone for that but my Dr wasn't sure it would start on time and I was anxious to start something asap, so i went for taxol starting shortly. She said she would be staryting the same trial in Singleton Hospital, swansea next year as well, it was just going throuhg the protocols at the moment. I dont have any maintenance treatments either.

Good luck 💗to you too

[COHEN123 in reply to Irisisme]

Merry christmas, just had Xmas breakfast which is always a good start to a fun day . 🎅Thanks for your reply Iris,

I'll wait and see how it goes and hope its manageable.

Absolutely good luck for next year ,

Lots of good wishes

Sue 🎅💗

[Leniko]

Hi- I’ve only had it in conjunction w Carbo. 6 treatments kept my OVCA away for 8 years. Praying for you! ❤️🙏

[COHEN123 in reply to Leniko]

Thanks Leniko. Glad you had a good response.

❤️

[NanB12 in reply to Leniko]

Hi Leniko:

That’s wonderful that the cancer stayed away for 8 years. I wanted to ask did you make any dietary changes, such as sugar intake or carbs or meat. Were you taking any supplements or vitamins during chemo? I am wondering as I did 5 rounds of carbo/taxol and it didn’t work. 😞 The cancer came back during chemo. This was after a hysterectomy and bilateral oophorectomy.

[Skyeplus]

Hi Sue, I hope you have had a good Christmas. My journey is very similar to yours although of course we are all unique. I was diagnosed in Aug 2021 and am stage 4a. I’ve had debulking surgery and three lots of carbo plus paclitaxel. I did have Niraparib for nearly a year but it stopped working and scans showed progression. After my last 6 lots of chemo and a scan, my oncologist said I had two options. A break with being monitored or paclitaxel every week with the fourth week nothing for I think six months. I asked him what he would do and he said have a break. I have been having chemo for nearly two years non stop. I now have peripheral neuropathy caused by the chemo. I took his advice and currently not having any treatment. BUT, I have bloods and a scan coming up so I guess it will show it’s growing again.

I hope your experience with paclitaxel goes well. I will be really interested to hear how it goes as I think I will be following you. I’m also really interested to find out about clinical trials. Sending love and lots of positive vibes for you Di xxxx

[COHEN123 in reply to Skyeplus]

Thanks Di, we do seem to be walking a similar path. We have had so much happen to us in two years and certainly too much chemo. My Dr thought it was important to start chemo again so I've gone with her advice. I've got neuropathy too. As you say there will be lots of differences in our story but I'll keep in touch with your story too.

Hope you had a good Christmas. I did and after a couple of happy busy days I'm enjoying a quieter one today.

Sue