Hormones and Aging: An Endocrine Society Scientific Statement" was presented at ENDO 2023

[BB001]

I haven't read it yet, but thought this looks interesting.

A Medscape article titled

'A 'One-Stop Shop': New Guidance on Hormones and Aging' stated:

'A new statement from The Endocrine Society on hormones and aging highlights the differences between normal aging and disease, and when treatment is and isn't appropriate.

The idea of the statement "is to be complete, but also to clarify some misunderstandings...We tried to be very clear in the language about what we know, where we can go, where we shouldn't go, and what we still need to learn," statement co-author Cynthia A. Stuenkel, MD, of the University of California, San Diego, told Medscape Medical News.

The document is divided into nine parts or axes: growth hormone, adrenal, ovarian, testicular, thyroid, osteoporosis, vitamin D deficiency, type 2 diabetes, and water metabolism. Each section covers natural history and observational data in older individuals, available therapies, clinical trial data on efficacy and safety in older individuals, bulleted "key points," and research gaps.

"Hormones and Aging: An Endocrine Society Scientific Statement" was presented at ENDO 2023: The Endocrine Society Annual Meeting and published online June 16 in the Journal of Clinical Endocrinology & Metabolism.

healthunlocked.com/redirect...

[Charlie-Farley]

Thank you for bringing to everyone’s attention- unbelievable 🙄

How can we possibly take this seriously?

When there are 20 year cohorts missing. Of course it is just this sort of research that drives policy.

See the graph - one can’t assume there is nothing to note by their absence, nor that they are the same as the cohort before or after, in which case the cohort s could have been combined (larger sample set better data , but not if it doesn’t give the answer wanted). It is simply a very incomplete data set. Especially concerning they have left out the start of a period of most dramatic hormonal changes (for women at least) after puberty and pregnancy - perimenopause……. 50 to 59 captured but nothing either side???? 🤔

I am always very uncomfortable with this sort of cherry picked data - do the other cohorts take away from the ‘story’?

[Charlie-Farley in reply to Charlie-Farley]

Graph - third time lucky?

TSH

[arTistapple]

Trust Charlie-Farley to get to the nub. My Masters degree is an Arts degree, not science. However I never cease to be amazed at what often passes for good research in science. Arts degrees are often considered inferior but SHEESHE! There is a lot to learn in medicine but it’s just not good enough to be spreading this stuff around. We know exactly who it appeals to and why.

[Charlie-Farley in reply to arTistapple]

I would have been embarrassed as a researcher to put this out there. Malcolm Kendrick bangs on about broken science and to be honest the more I see the more I agree.

[arTistapple]

There appears to be no shame these days. Tick box systems are everywhere. Who would have thought that amateurs would be running our Health services? These new practitioners (can’t remember the name offhand) can’t be any worse than what we have already. Doctors don’t seem to understand they really ought to have stood up for patients, not only pay scales. They themselves are contributing to this farce that is unfolding.