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Levodopa Medications and Vitamin B6
Introduction
Vitamin B6 is a cofactor in over 100 enzymatic reactions. In the process it is converted from the active form, principally P5P (pyridoxal-5-phosphate), to the inactive form, pyridoxine. An excess of pyridoxine is toxic because it occupies sites that require the active form. For this
Introduction
Vitamin B6 is a cofactor in over 100 enzymatic reactions. In the process it is converted from the active form, principally P5P (pyridoxal-5-phosphate), to the inactive form, pyridoxine. An excess of pyridoxine is toxic because it occupies sites that require the active form. For this
park_bear
in
Cure Parkinson's
6 years ago
Six months off all forms of b12
Hi I’ve been off all forms of b12 for six months now and got a serum b12 of 241pmol/l and an active b12 of 127 pmol/l on 21/11/17 (its 9/12/17 today). Does this mean I’m not b12d? I began self injecting back in April but had to stop due to developing awful anxiety after each one and then some very negative
Hi I’ve been off all forms of b12 for six months now and got a serum b12 of 241pmol/l and an active b12 of 127 pmol/l on 21/11/17 (its 9/12/17 today). Does this mean I’m not b12d? I began self injecting back in April but had to stop due to developing awful anxiety after each one and then some very negative
Steap
in
Pernicious Anaemia Society
6 years ago
Peripheral Neuropathy pain
I was diagnosed 1991 with CMT type 1(a) I am 67 now and had my knees replaced , my toes staightened etc etc. I get periferal neuropathy pains on just one toe. It last for 3_4 days and by using the T.E.N.S machine it allows me to get some sleep. Is there anything out there that would be helpful ? I walk
I was diagnosed 1991 with CMT type 1(a) I am 67 now and had my knees replaced , my toes staightened etc etc. I get periferal neuropathy pains on just one toe. It last for 3_4 days and by using the T.E.N.S machine it allows me to get some sleep. Is there anything out there that would be helpful ? I walk
Tandarts
in
Charcot-Marie-Tooth UK
6 years ago
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Advice sought on peripheral neuropathy and doctors
I have suffered with uncomfortable feet with an unpleasant sensation crawling up my legs for well over a year. I had put it down to another auto immune disease that falls into the uncommon group so not a huge amount of information available other from those with the disease and their experiences. I
I have suffered with uncomfortable feet with an unpleasant sensation crawling up my legs for well over a year. I had put it down to another auto immune disease that falls into the uncommon group so not a huge amount of information available other from those with the disease and their experiences. I
butterflyEi
in
Pain Concern
6 years ago
selegiline and mortality
Comparison of therapeutic effects and mortality data of levodopa and levodopa combined with selegiline in patients with early, mild Parkinson's disease Levodopa in combination with selegiline seemed to confer no clinical benefit over levodopa alone in treating early, mild Parkinson's disease. Moreover
Comparison of therapeutic effects and mortality data of levodopa and levodopa combined with selegiline in patients with early, mild Parkinson's disease Levodopa in combination with selegiline seemed to confer no clinical benefit over levodopa alone in treating early, mild Parkinson's disease. Moreover
Hidden
in
Cure Parkinson's
6 years ago
Peripheral Neuropathy
Does anyone know if there is a link between peripheral neuropathy and hypothyroidism? I have seen my GP recently because of unexplained pain in two of my toes on my left foot. She said it could be due to neuropathy and has referred me for a scan of my foot. I know my B12 was low on my last blood test
Does anyone know if there is a link between peripheral neuropathy and hypothyroidism? I have seen my GP recently because of unexplained pain in two of my toes on my left foot. She said it could be due to neuropathy and has referred me for a scan of my foot. I know my B12 was low on my last blood test
Citta
in
Thyroid UK
6 years ago
Numbness and tingling problem
Hello dear all I m facing problem of numbness in legs alongwith tingling.my present hb1ac is 6.3.i also hv backache.i m taking b12.may be due to peripheral neuropathy..i m given calcium pantothenate.i m not on any med.
Hello dear all I m facing problem of numbness in legs alongwith tingling.my present hb1ac is 6.3.i also hv backache.i m taking b12.may be due to peripheral neuropathy..i m given calcium pantothenate.i m not on any med.
Manie
in
Diabetes India
6 years ago
Feet and ankles are screaming at me!
Sorry for being dramatic, but I'm so fed up with my feet and ankles. They are always a problem for me but at the moment they are awful, making walking anywhere a misery. I have sharp pain in ankles and constant burning on the top of my feet and toes. I can't find anything remotely comfortable to wear
Sorry for being dramatic, but I'm so fed up with my feet and ankles. They are always a problem for me but at the moment they are awful, making walking anywhere a misery. I have sharp pain in ankles and constant burning on the top of my feet and toes. I can't find anything remotely comfortable to wear
creaky
in
LUPUS UK
6 years ago
Csf protein
Did anybody have raised csf protein levels as part of their Vasculitis investigations
Did anybody have raised csf protein levels as part of their Vasculitis investigations
Perkles
in
Vasculitis UK
6 years ago
How To Stop and Prevent Sarcopenia (loss of muscle mass and strength)
"Sarcopenia, the loss of muscle mass and strength, becomes more common with age and can decrease lifespan and quality of life. "Eating enough calories and high-quality protein can slow down the rate of muscle loss. Omega-3 and creatine supplements may also help fight sarcopenia. "Nevertheless, exercising
"Sarcopenia, the loss of muscle mass and strength, becomes more common with age and can decrease lifespan and quality of life. "Eating enough calories and high-quality protein can slow down the rate of muscle loss. Omega-3 and creatine supplements may also help fight sarcopenia. "Nevertheless, exercising
PDConscience
in
Cure Parkinson's
6 years ago
RLS/Pain with BP and sugar
Hi every one, I am new in the group. My mother suffering from RLS in legs and in arms and pain in lega as well along with rest less legs since 10 years. She is currently using Ropinirol 1mg at night and 1mg after breakfast + Pregabalin 75mg, but she is not getting normal , i mean she feel relax sometimes
Hi every one, I am new in the group. My mother suffering from RLS in legs and in arms and pain in lega as well along with rest less legs since 10 years. She is currently using Ropinirol 1mg at night and 1mg after breakfast + Pregabalin 75mg, but she is not getting normal , i mean she feel relax sometimes
Wajidali25
in
Restless Legs Syndrome
6 years ago
Tingling/ numbness improved after SI but is now getting worse again!
Hi again x I was doing well SI every other day for 3 weeks and the tingling and numbness had completely gone. I then reduced SI down to twice a week and the tingling started to come back. I went back to alternate days and it improved for a week or so and now it's back almost all the time. I know I read
Hi again x I was doing well SI every other day for 3 weeks and the tingling and numbness had completely gone. I then reduced SI down to twice a week and the tingling started to come back. I went back to alternate days and it improved for a week or so and now it's back almost all the time. I know I read
Padders12
in
Pernicious Anaemia Society
6 years ago
Canvas
Hello, I've been diagnosed with Canvas. It's rare, but if you have it too, let's chat. In case you're wondering what it is - cerebellar ataxia neuropathy vestibular areflexia syndrome. My neurologist is at Columbia in NYC and I see her every 4 months. I live in upstate NY. Anybody out there?
Hello, I've been diagnosed with Canvas. It's rare, but if you have it too, let's chat. In case you're wondering what it is - cerebellar ataxia neuropathy vestibular areflexia syndrome. My neurologist is at Columbia in NYC and I see her every 4 months. I live in upstate NY. Anybody out there?
Mmenergy
in
Neuropathy Support
6 years ago
PD and iodine deficiency?
He earned his Doctor of
Naturopathy
from the Trinity School of Natural Health.
He earned his Doctor of
Naturopathy
from the Trinity School of Natural Health.
faridaro
in
Cure Parkinson's
7 years ago
Am I a carrier of CMT
My son in his forties was diagnosed about 8 years ago in South Africa . I think he said it was type 1 , he said the Nurologist said I passed it on to him, it really upset me to be honest, I. have had different problems with numbness and tingling in my legs / feet for years , I have not seen anyone about
My son in his forties was diagnosed about 8 years ago in South Africa . I think he said it was type 1 , he said the Nurologist said I passed it on to him, it really upset me to be honest, I. have had different problems with numbness and tingling in my legs / feet for years , I have not seen anyone about
Linnikins
in
Charcot-Marie-Tooth UK
6 years ago
Hi I’m new
Hi there, my name is Lucy I’m 31 almost 32, I have 4 children. I was born with a mirror arm which means I have no radius and two ulner bones. My shoulder is crumbling and the nerves are all trapped in between bones. I also have rheumatoid arthritis which is agony. I’m so fed up with being in pain everyday
Hi there, my name is Lucy I’m 31 almost 32, I have 4 children. I was born with a mirror arm which means I have no radius and two ulner bones. My shoulder is crumbling and the nerves are all trapped in between bones. I also have rheumatoid arthritis which is agony. I’m so fed up with being in pain everyday
Lucywaggott
in
Pain Concern
6 years ago
New to the group
Hi all, I have just joined as after years of poor sleep And not understanding why I think I have restless leg syndrome. For years I’ve had sensations in my legs that are hard to describe but inside my legs feels itchy like insects are crawling in them. I have tried everything I can think of to stop
Hi all, I have just joined as after years of poor sleep And not understanding why I think I have restless leg syndrome. For years I’ve had sensations in my legs that are hard to describe but inside my legs feels itchy like insects are crawling in them. I have tried everything I can think of to stop
lolly3110
in
Restless Legs Syndrome
6 years ago
Everyday Life. e.s.a. stopped.
I am finding I am getting more and more forgetful, absent minded. I don't listen. getting more clumsy and lack concentration. Nothing like this came up in my assessment I attended. the forms are all about physical more than mental. in the physical side where I have problems with aching limbs, back etc
I am finding I am getting more and more forgetful, absent minded. I don't listen. getting more clumsy and lack concentration. Nothing like this came up in my assessment I attended. the forms are all about physical more than mental. in the physical side where I have problems with aching limbs, back etc
Mandypandy1969
in
LUPUS UK
6 years ago
Nerve block and rfd, then problem sleeping on left side
Did anyone ever have two successful nerve blocks and then the rfd or burning of nerves on one side of spine and then experience numbness and tingling on one side while trying to sleep? Then they have to turn back over cause it gets so uncomfortable to sleep on that side? It also feels like when you laid
Did anyone ever have two successful nerve blocks and then the rfd or burning of nerves on one side of spine and then experience numbness and tingling on one side while trying to sleep? Then they have to turn back over cause it gets so uncomfortable to sleep on that side? It also feels like when you laid
betabyte
in
Pain Concern
6 years ago
Alternative Treatment for RA
On a phone call with my father, He said that Vietnamese
naturopathy
has a formula for this but he does not remember the exact ingredients. It is kind of tough for 91 years old memory. So he advised me to call my cousin for more details.
On a phone call with my father, He said that Vietnamese
naturopathy
has a formula for this but he does not remember the exact ingredients. It is kind of tough for 91 years old memory. So he advised me to call my cousin for more details.
HDo2010
in
NRAS
7 years ago
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