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IMPORTANT: Nicotinamide riboside (or NAD+ or Tru Niagen) may be involved in neoplastic and metastatic processes
Here is the reference: A bioluminescent-based probe for in vivo non-invasive monitoring of nicotinamide riboside uptake reveals a link between
metastasis
and NAD+ metabolism": https://www.sciencedirect.com/science/article/pii/S0956566322008661 I also took nicotinamide riboside, luckily just for
Here is the reference: A bioluminescent-based probe for in vivo non-invasive monitoring of nicotinamide riboside uptake reveals a link between
metastasis
and NAD+ metabolism": https://www.sciencedirect.com/science/article/pii/S0956566322008661 I also took nicotinamide riboside, luckily just for
enjoy2013
in
Restless Legs Syndrome
2 years ago
Reoccurance
I read about it and seems it is used in instances of peritoneal
metastasis
of colorectal cancer. Any feedback on this will be helpful..thanks a ton.
I read about it and seems it is used in instances of peritoneal
metastasis
of colorectal cancer. Any feedback on this will be helpful..thanks a ton.
msuspartan
in
My Ovacome
2 years ago
High Alkaline Phosphatase and knee/bone pain side effects with Venetoclax/Obinituzumab
My research indicates that the cause of the elevated Alkaline Phosphatase could be anything from thyroid conditions, to conditions such as Osteomalacia or Paget’s disease that weaken bones, to bone
metastasis
or Osteogenic sarcoma (both cancer in bones).
My research indicates that the cause of the elevated Alkaline Phosphatase could be anything from thyroid conditions, to conditions such as Osteomalacia or Paget’s disease that weaken bones, to bone
metastasis
or Osteogenic sarcoma (both cancer in bones).
DinosaurDad
in
CLL Support
2 years ago
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Phase 2 EXTEND randomised trial finds adding metastasis directed therapy with radiation to intermittent hormone therapy improves outcomes.
Addition of
metastasis
-directed therapy to intermittent hormone therapy for oligometastatic prostate cancer (EXTEND): A multicenter, randomized phase II trial. Presented at: ASTRO 2022 Annual Meeting, October 23-26, San Antonio, Texas. Abstract LBA 05.
Addition of
metastasis
-directed therapy to intermittent hormone therapy for oligometastatic prostate cancer (EXTEND): A multicenter, randomized phase II trial. Presented at: ASTRO 2022 Annual Meeting, October 23-26, San Antonio, Texas. Abstract LBA 05.
Graham49
in
Advanced Prostate Cancer
2 years ago
Why we add an AART drug to ADT?
The ARAMIS trial in nmCRPC showed increased
metastasis
free survival of 40.4 vs 18.4 months. And PSA progression (resistance) was 33 months vs 7.3 months.
The ARAMIS trial in nmCRPC showed increased
metastasis
free survival of 40.4 vs 18.4 months. And PSA progression (resistance) was 33 months vs 7.3 months.
MateoBeach
in
Fight Prostate Cancer
1 year ago
Nubeqa failing onto C-94676 clinical trial
You can view my profile but in a nutshell went to a free screening in the fall of 2012 but they never contacted me until early 2013 where 12 core biopsy revealed Stage IV M1b with extensive lymph node and pelvic and spinal skeletal
metastasis
.
You can view my profile but in a nutshell went to a free screening in the fall of 2012 but they never contacted me until early 2013 where 12 core biopsy revealed Stage IV M1b with extensive lymph node and pelvic and spinal skeletal
metastasis
.
wagscure259
in
Advanced Prostate Cancer
2 years ago
A Different View on Bone Protection
By end stage, over 90% will have multiple bone
metastasis
with often severe pain and pathological fractures.Bone protective medications, chiefly denosumab and zolendronic acid. Are used as treatments for osteopenia/osteoporosis as shown on a DEXA scan.
By end stage, over 90% will have multiple bone
metastasis
with often severe pain and pathological fractures.Bone protective medications, chiefly denosumab and zolendronic acid. Are used as treatments for osteopenia/osteoporosis as shown on a DEXA scan.
MateoBeach
in
Fight Prostate Cancer
2 years ago
Luteolin Inhibits Human Prostate Tumor Growth by Suppressing Vascular Endothelial Growth Factor Receptor 2-Mediated Angiogenesis
.], and Xianglin Shi Additional article information Abstract Angiogenesis, the formation of new blood vessels from pre-existing vascular beds, is essential for tumor growth, invasion, and
metastasis
. Luteolin is a common dietary flavonoid found in fruits and vegetables.
.], and Xianglin Shi Additional article information Abstract Angiogenesis, the formation of new blood vessels from pre-existing vascular beds, is essential for tumor growth, invasion, and
metastasis
. Luteolin is a common dietary flavonoid found in fruits and vegetables.
GeorgeGlass
in
Advanced Prostate Cancer
2 years ago
New metastasis found
Additional focus of choline uptake in the sternum near the sternomanubrial joint is more prominent on prior exam and is also worrisome for
metastasis
. 2.
Additional focus of choline uptake in the sternum near the sternomanubrial joint is more prominent on prior exam and is also worrisome for
metastasis
. 2.
swwags
in
Advanced Prostate Cancer
2 years ago
Ravid Straussman & the Tumor Biome
Most importantly, there is still a lot that we do not know about the different effects that intra-tumor bacteria may have on different aspects of tumor biology like response to drugs, effects on tumor immunity, angiogenesis,
metastasis
, and tumor metabolism.
Most importantly, there is still a lot that we do not know about the different effects that intra-tumor bacteria may have on different aspects of tumor biology like response to drugs, effects on tumor immunity, angiogenesis,
metastasis
, and tumor metabolism.
pca2004
in
Fight Prostate Cancer
1 year ago
Ibrance plus letrozole working
I’ve been taking Ibrance 75 mg two weeks on two weeks off for 3 1/2 years Took a while to get the Ibrance balance. I take letrozole daily. Scans taken every 4 months have shown no progression. I had a double mastectomy and bone lesions on my spine. I followed Joe Tippens protocol for 2 years. I did
I’ve been taking Ibrance 75 mg two weeks on two weeks off for 3 1/2 years Took a while to get the Ibrance balance. I take letrozole daily. Scans taken every 4 months have shown no progression. I had a double mastectomy and bone lesions on my spine. I followed Joe Tippens protocol for 2 years. I did
myrtice
in
SHARE Metastatic Breast Cancer
2 years ago
Taxol or Navelbine?
After what was seen as excellent results after first MRI on Cape, 2nd MRI not so dandy! It worked very well on mets in my liver mets and no mention of femur but there has been unwanted activity “progression of the right interpectoral lyphadenopathy and other chest wall disease”. . My onc called me
After what was seen as excellent results after first MRI on Cape, 2nd MRI not so dandy! It worked very well on mets in my liver mets and no mention of femur but there has been unwanted activity “progression of the right interpectoral lyphadenopathy and other chest wall disease”. . My onc called me
Ntash01
in
SHARE Metastatic Breast Cancer
2 years ago
Trastuzumab Deruxtecan Extends Survival Over Chemotherapy for Patients With HER2-Positive Metastatic Breast Cancer
Trastuzumab deruxtecan (T-DXd) was associated with higher response rates and longer survival than capecitabine-based regimens for [i]
third-line treatment of patients with HER2-positive metastatic breast cancer
[/i]previously treated with trastuzumab emtansine (T-DM1), according to a study presented
Trastuzumab deruxtecan (T-DXd) was associated with higher response rates and longer survival than capecitabine-based regimens for [i]
third-line treatment of patients with HER2-positive metastatic breast cancer
[/i]previously treated with trastuzumab emtansine (T-DM1), according to a study presented
Hazelgreen
in
SHARE Metastatic Breast Cancer
2 years ago
CTC counts may be the way of the future...
Published in Metastatic Breast Cancer and News · December 16, 2022 SABCS 2022: Using Circulating Tumor Cell Count to Guide Treatment Decisions Improved Overall Survival in Patients With Metastatic Breast Cancer Patients gained 16 months in median overall survival
if they received chemotherapy
Published in Metastatic Breast Cancer and News · December 16, 2022 SABCS 2022: Using Circulating Tumor Cell Count to Guide Treatment Decisions Improved Overall Survival in Patients With Metastatic Breast Cancer Patients gained 16 months in median overall survival
if they received chemotherapy
Hazelgreen
in
SHARE Metastatic Breast Cancer
2 years ago
Ongoing symptoms of ET
Published in Oncology Journal Scan / Research · December 21, 2022 Long-Term Sequelae of Endocrine Therapy Among the Survivors of Breast Cancer Breast Cancer Research and Treatment TAKE-HOME MESSAGE This observational study reported the long-term sequelae of endocrine therapy (ET) among the survivors
Published in Oncology Journal Scan / Research · December 21, 2022 Long-Term Sequelae of Endocrine Therapy Among the Survivors of Breast Cancer Breast Cancer Research and Treatment TAKE-HOME MESSAGE This observational study reported the long-term sequelae of endocrine therapy (ET) among the survivors
Hazelgreen
in
SHARE Metastatic Breast Cancer
2 years ago
Brain metastasis treatment options?
Hi everyone, I’ve only written here once before about my dad’s (62) battle with prostate cancer (Stage 3, Gleason 9 at dx May 2019). Sadly we’ve had yet more bad news over these past two weeks. Last summer we learned that his cancer had spread to one isolated nodule on his lung (oligometastasis - very
Hi everyone, I’ve only written here once before about my dad’s (62) battle with prostate cancer (Stage 3, Gleason 9 at dx May 2019). Sadly we’ve had yet more bad news over these past two weeks. Last summer we learned that his cancer had spread to one isolated nodule on his lung (oligometastasis - very
Bradshawsl
in
Advanced Prostate Cancer
2 years ago
Update to Pluvicto Consult, and Question
My dad still complains of aches almost daily, is this common with bone
metastasis
? Does anyone else experience this? He does have arthritis, but I feel this is more the cancer. He often has to take Tylenol daily but he says that does the trick.
My dad still complains of aches almost daily, is this common with bone
metastasis
? Does anyone else experience this? He does have arthritis, but I feel this is more the cancer. He often has to take Tylenol daily but he says that does the trick.
Sunnyday1122
in
Advanced Prostate Cancer
2 years ago
I was meant to get my ovaries out but a peak under the hood showed wide spread cancer through out my abdomen… on to cape.
So I am off verzenio and suddenly feel really well! So well that I am dragging my feet on starting Xeloda and facing hand foot etc. what what all do right away to prepare for potential issues? I lready have in grown toes and am afraid that will balloon into a bigger problem… foot dr? Any creams you
So I am off verzenio and suddenly feel really well! So well that I am dragging my feet on starting Xeloda and facing hand foot etc. what what all do right away to prepare for potential issues? I lready have in grown toes and am afraid that will balloon into a bigger problem… foot dr? Any creams you
Bettybuckets
in
SHARE Metastatic Breast Cancer
2 years ago
What is after Taxol?
Trying to get ahead of some decisions as it seems that I am a one year treatment gal...Ibrance - 1 year, Xeloda - 1 year, now Taxol seems to be giving up on me after a year too. Doc rattled off things like Gemzar and said that there were a lot of treatments that used to be only for triple negative that
Trying to get ahead of some decisions as it seems that I am a one year treatment gal...Ibrance - 1 year, Xeloda - 1 year, now Taxol seems to be giving up on me after a year too. Doc rattled off things like Gemzar and said that there were a lot of treatments that used to be only for triple negative that
Iwasborntodothis
in
SHARE Metastatic Breast Cancer
2 years ago
Sequencing of Androgen-Deprivation Therapy of Short Duration With Radiotherapy for Nonmetastatic Prostate Cancer (SANDSTORM) - ASCO Journal
IPTW-adjusted Fine and Gray competing risk models were built to evaluate distant
metastasis
(DM) and prostate cancer–specific mortality.
IPTW-adjusted Fine and Gray competing risk models were built to evaluate distant
metastasis
(DM) and prostate cancer–specific mortality.
cujoe
in
Fight Prostate Cancer
2 years ago
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