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Glyburide / Metformin
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SGLT-2 Inhibitors to (partially) “Starve” Glucose Dependent Cancers
There has been many theories proposed about how to “starve cancer”. And many have gone down rabbit holes chasing unproven theories about how to do so. Unfortunately, IMO, they simply do not work. Cancers are very metabolically flexible. They will take what they need to survive and grow and adapt to whatever
There has been many theories proposed about how to “starve cancer”. And many have gone down rabbit holes chasing unproven theories about how to do so. Unfortunately, IMO, they simply do not work. Cancers are very metabolically flexible. They will take what they need to survive and grow and adapt to whatever
MateoBeach
in
Fight Prostate Cancer
1 year ago
Peter Attia -Journal club with Andrew Huberman: metformin as a geroprotective drug, the power of belief, and how to read scientific papers
Why Peter no longer takes Metformin and why believing that a drug will work helps make ir happen https://peterattiamd.com/andrewhuberman2/?utm_source=podcast-email&utm_medium=email&utm_campaign=230911-pod-andrewhuberman2&utm_content=230911-pod-andrewhuberman2-email-nonsubs&mc_cid=31e952e2dd&mc_eid=ee5f4da697
Why Peter no longer takes Metformin and why believing that a drug will work helps make ir happen https://peterattiamd.com/andrewhuberman2/?utm_source=podcast-email&utm_medium=email&utm_campaign=230911-pod-andrewhuberman2&utm_content=230911-pod-andrewhuberman2-email-nonsubs&mc_cid=31e952e2dd&mc_eid=ee5f4da697
Scout4answers
in
Advanced Prostate Cancer
1 year ago
Peter Attia ‒ with Andrew Huberman: metformin as a geroprotective drug, the power of belief, and how to read scientific papers
Why Peter no longer takes Metformin and why believing that a drug will work helps make it happen https://peterattiamd.com/andrewhuberman2/?utm_source=podcast-email&utm_medium=email&utm_campaign=230911-pod-andrewhuberman2&utm_content=230911-pod-andrewhuberman2-email-nonsubs&mc_cid=31e952e2dd&mc_eid
Why Peter no longer takes Metformin and why believing that a drug will work helps make it happen https://peterattiamd.com/andrewhuberman2/?utm_source=podcast-email&utm_medium=email&utm_campaign=230911-pod-andrewhuberman2&utm_content=230911-pod-andrewhuberman2-email-nonsubs&mc_cid=31e952e2dd&mc_eid
Scout4answers
in
Fight Prostate Cancer
1 year ago
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2 questions i asked chat open AI mostly beyond my understanding but might be of interest to some of you :)
Q1 Which drugs could be re purposed to stimulate autophagy? ChatGPT Autophagy is a natural cellular process through which the body cleans out damaged cells and regenerates new, healthy ones. It plays a crucial role in maintaining cellular health and has been implicated in various diseases including
Q1 Which drugs could be re purposed to stimulate autophagy? ChatGPT Autophagy is a natural cellular process through which the body cleans out damaged cells and regenerates new, healthy ones. It plays a crucial role in maintaining cellular health and has been implicated in various diseases including
JustJeff
in
Cure Parkinson's
1 year ago
just 1 follicle
I’m currently undergoing follicle tracking on natural ovulation for PCOS. I’ve had 4 miscarriages due to low progesterone so need to go on the pessaries as soon as I get pregnant, as my problem is the embryo is implanting but soon miscarries as I can’t maintain my lining for some reason. Anyway, I had
I’m currently undergoing follicle tracking on natural ovulation for PCOS. I’ve had 4 miscarriages due to low progesterone so need to go on the pessaries as soon as I get pregnant, as my problem is the embryo is implanting but soon miscarries as I can’t maintain my lining for some reason. Anyway, I had
Amy190
in
PCOS UK (Verity)
1 year ago
only one follicle :(
hi all, I’m currently undergoing follicle tracking on natural ovulation for PCOS. I’ve had 4 miscarriages due to low progesterone so need to go on the pessaries as soon as I get pregnant, as my problem is the embryo is implanting but soon miscarries as I can’t maintain my lining for some reason. Anyway
hi all, I’m currently undergoing follicle tracking on natural ovulation for PCOS. I’ve had 4 miscarriages due to low progesterone so need to go on the pessaries as soon as I get pregnant, as my problem is the embryo is implanting but soon miscarries as I can’t maintain my lining for some reason. Anyway
Amy190
in
Fertility Network UK
1 year ago
Drug side effects
Last month I went from prediabetic to hitting 300 due to the Dexamethasone I've been having to take for my chemo treatments. My oncologist put me on metformin & it brought my level down, but now I've been in & out of the ER. Once with intestinal issues, once with chronic diarrhea & shortness of breath
Last month I went from prediabetic to hitting 300 due to the Dexamethasone I've been having to take for my chemo treatments. My oncologist put me on metformin & it brought my level down, but now I've been in & out of the ER. Once with intestinal issues, once with chronic diarrhea & shortness of breath
OneLump22
in
SHARE Metastatic Breast Cancer
1 year ago
Letrozole - slow follicle growth - any experiences ?
Hello, I’m worried about my current cycle where I’m was treated with letrozole 5mg days 2-6. I have PCO (and usually ovulate on my own around day 14). I’m on letrozole to boost ovulation and to help my short natural Luteal phase (also take progesterone in the Luteal phase). For the past 6 cycles
Hello, I’m worried about my current cycle where I’m was treated with letrozole 5mg days 2-6. I have PCO (and usually ovulate on my own around day 14). I’m on letrozole to boost ovulation and to help my short natural Luteal phase (also take progesterone in the Luteal phase). For the past 6 cycles
CarlottaD27
in
Fertility Network UK
1 year ago
Orgovyx Insurance Approval
Anyone who is not on Medicare but relying on private insurance in getting approval for Orgovyx? I really want to avoid Lupron or Eligard since I take two blood pressure meds, one statin and Metformin for type 2 diabetes already. Plus, I have heard nothing but bad things about both. Yes, I realize
Anyone who is not on Medicare but relying on private insurance in getting approval for Orgovyx? I really want to avoid Lupron or Eligard since I take two blood pressure meds, one statin and Metformin for type 2 diabetes already. Plus, I have heard nothing but bad things about both. Yes, I realize
805guy
in
Prostate Cancer Network
1 year ago
Pre diabetes
on metformin pre diabetes of 42 taking 500 mg metformin twice a day, do I still need to take it.
on metformin pre diabetes of 42 taking 500 mg metformin twice a day, do I still need to take it.
elwins
in
Healthy Evidence
1 year ago
... what, then, do we die of?
New study of SEER data below [1]. The old comforting words that men with PCa "die with the disease, not of it" does not apply once mets occur, of course, but is largely true for local disease (the majority of cases in the U.S., due to screening practices.) It has long been known that men with PCa
New study of SEER data below [1]. The old comforting words that men with PCa "die with the disease, not of it" does not apply once mets occur, of course, but is largely true for local disease (the majority of cases in the U.S., due to screening practices.) It has long been known that men with PCa
pca2004
in
Fight Prostate Cancer
1 year ago
Dr. Mark Porter's B12 Times article
Further to deniseinmilden's post I decided to risk my credit card and subscribed to the free trial of The Times to get the article. Here it is, for better or for worse! There are a lot of comments, some of which he replies to, sadly I can't reproduce them here. But I think it's good news in terms of the
Further to deniseinmilden's post I decided to risk my credit card and subscribed to the free trial of The Times to get the article. Here it is, for better or for worse! There are a lot of comments, some of which he replies to, sadly I can't reproduce them here. But I think it's good news in terms of the
Sneedle
in
Pernicious Anaemia Society
1 year ago
A1C in CKD
hello. has anyone heard that the A1C "goal" for a diabetic is not the same if the diabetic has CKD? since I started diabetic treatment 2.5 years ago, it seems like my Dr's have focused on my A1C only. my A1C goes down to 6.4 great. but the Metformin can be hard to take at times with side effects,
hello. has anyone heard that the A1C "goal" for a diabetic is not the same if the diabetic has CKD? since I started diabetic treatment 2.5 years ago, it seems like my Dr's have focused on my A1C only. my A1C goes down to 6.4 great. but the Metformin can be hard to take at times with side effects,
Alexie90
in
Kidney Disease
1 year ago
ADT and Headaches
To all, I may have mentioned it before, but I've had low-level but disruptive headaches since I started ADT along with low RBC/Hemoglobin/Hematocrit. Also as a diabetic, I've been on metformin for many years, thus depleting my B12 levels. I've talked to my doctors about this, and the only solution
To all, I may have mentioned it before, but I've had low-level but disruptive headaches since I started ADT along with low RBC/Hemoglobin/Hematocrit. Also as a diabetic, I've been on metformin for many years, thus depleting my B12 levels. I've talked to my doctors about this, and the only solution
fmh1
in
Advanced Prostate Cancer
1 year ago
PCOS and Metformin
Hello, I’m new here and hoping for some advice. I’ve been properly ttc since September 2022 and been off birth control since Jan 22 as I wanted to get my body back to normal (not happened :()Recently been diagnosed with PCOs. I have high levels of AMH and both ovaries have follicles. I’ve had no period
Hello, I’m new here and hoping for some advice. I’ve been properly ttc since September 2022 and been off birth control since Jan 22 as I wanted to get my body back to normal (not happened :()Recently been diagnosed with PCOs. I have high levels of AMH and both ovaries have follicles. I’ve had no period
SD9320
in
PCOS UK (Verity)
1 year ago
Jardiance side effects? Off Metformin for diabetes 2, but high blood sugar 88, overweight, aged 67, scared reactions due other conditions?
Am terminally ill, irreparable brain damage, epilepsy, so can't do much exercise! Was on metformin from start of diabetes 2 in 2020, found my blood sugar level was 88, have been dieting lost 2 half stone, cholesterol not too bad, so they have put me on just Jardiance 10mg a day! Am taking medication
Am terminally ill, irreparable brain damage, epilepsy, so can't do much exercise! Was on metformin from start of diabetes 2 in 2020, found my blood sugar level was 88, have been dieting lost 2 half stone, cholesterol not too bad, so they have put me on just Jardiance 10mg a day! Am taking medication
Adlon57
in
Healthy Evidence
1 year ago
Metformin and Pregnacare
Hi, Just to check is it safe taking metformin and pregnacare before pregnancy as supplement together? is there any side effects ? We are trying to get pregnant naturally Any help would be highly appreciated. Many thanks
Hi, Just to check is it safe taking metformin and pregnacare before pregnancy as supplement together? is there any side effects ? We are trying to get pregnant naturally Any help would be highly appreciated. Many thanks
Ana9044
in
PCOS UK (Verity)
1 year ago
Trialling magnesium
Been looking for an answer to RLS since my twenties. At one stage I thought the cause might be beer but managed to eliminate that as the prime suspect, thank goodness. Tried ginko biloba tablets, thought we were doing well but eventually lost faith in that. Over the years it was only intermittent and
Been looking for an answer to RLS since my twenties. At one stage I thought the cause might be beer but managed to eliminate that as the prime suspect, thank goodness. Tried ginko biloba tablets, thought we were doing well but eventually lost faith in that. Over the years it was only intermittent and
50568789
in
Restless Legs Syndrome
1 year ago
WOW, noticing today, after some weak days at 5mg prednisone, I am again feeling good and energetic, added meth and hydroxy dropped metformin
I was at 5 a few weeks go, but too hastily dropped and went to 2.5, and on the 3rd day at 2.5 felt terrible. Jumped back to 10 and then 7.5. And since I have gone back to 5, after maybe a week at 5, I am again feeling great, better than I did the last time I was at 5. There are some differences now,
I was at 5 a few weeks go, but too hastily dropped and went to 2.5, and on the 3rd day at 2.5 felt terrible. Jumped back to 10 and then 7.5. And since I have gone back to 5, after maybe a week at 5, I am again feeling great, better than I did the last time I was at 5. There are some differences now,
sdowney717
in
PMRGCAuk
1 year ago
Colchicine and Inflammation Revisited
Inflammation is one of the two principle drivers of “The Hallmarks of Cancer” which are the common drivers of progression of cancer from initiation to invasion and spread, to developing resistance to treatments and ultimately to end stage metastasis. (The other main driver being genomic instability:
Inflammation is one of the two principle drivers of “The Hallmarks of Cancer” which are the common drivers of progression of cancer from initiation to invasion and spread, to developing resistance to treatments and ultimately to end stage metastasis. (The other main driver being genomic instability:
MateoBeach
in
Advanced Prostate Cancer
1 year ago
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