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Early Results from Transdermal Estrogen PATCH trial - 2
Here's some charts comparing Lupron ADT to transdermal estrogen (TDE) patch therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment. For Lupron, 65% of HR/
Here's some charts comparing Lupron ADT to transdermal estrogen (TDE) patch therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment. For Lupron, 65% of HR/
janebob99
in
Advanced Prostate Cancer
4 months ago
Early Results from Transdermal Estrogen PATCH trial
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
janebob99
in
Advanced Prostate Cancer
4 months ago
Early Results of Estrogen PATCH trial - 1
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
janebob99
in
Prostate Cancer Network
4 months ago
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HRT and waiting for scans
Earlier this year in March, I saw my GP to ask about HRT, so blood works were done and anomalies found so went for an ultrasound and found to have Fatty liver and hepatic hemangioma. I'm now waiting for a fibroscsn in December and I'm worried and scared. To help myself I've stopped alcohol completely
Earlier this year in March, I saw my GP to ask about HRT, so blood works were done and anomalies found so went for an ultrasound and found to have Fatty liver and hepatic hemangioma. I'm now waiting for a fibroscsn in December and I'm worried and scared. To help myself I've stopped alcohol completely
Hidden
in
British Liver Trust
9 months ago
Estrogen ADT vs Lupron ADT
Here's a chart showing % of men who have a given condition, comparing Estrogen ADT versus Lupron ADT. There's big reduction in hot flashes, and improvements in libido, when taking supplemental Estrogen. Estrogen increases gynecomastia (enlarged breasts), however. Bob
Here's a chart showing % of men who have a given condition, comparing Estrogen ADT versus Lupron ADT. There's big reduction in hot flashes, and improvements in libido, when taking supplemental Estrogen. Estrogen increases gynecomastia (enlarged breasts), however. Bob
janebob99
in
Prostate Cancer Network
4 months ago
Is it menopause ?
My story is complicated and confusing. I am 39 now but I think I am getting into menopause very soon.I have severe hot flushes for nearly a month and half now, they are so severe and frequent that I have to sit motionless in front of the AC or fan all the time, even going to the bathroom would trigger
My story is complicated and confusing. I am 39 now but I think I am getting into menopause very soon.I have severe hot flushes for nearly a month and half now, they are so severe and frequent that I have to sit motionless in front of the AC or fan all the time, even going to the bathroom would trigger
veryanxious84
in
Menopause and Perimenopause Support
9 months ago
given up
Hello, I was wondering if anyone could possibly help me with some advice. Unfortunately, because I am under 60 years of age, I have basically been told I will not get a knee replacement until I am 60 or over, but I am now unable to weigh bare because of my knees, and I do mean unable to even put any
Hello, I was wondering if anyone could possibly help me with some advice. Unfortunately, because I am under 60 years of age, I have basically been told I will not get a knee replacement until I am 60 or over, but I am now unable to weigh bare because of my knees, and I do mean unable to even put any
Jinnty89
in
My EXI Community
5 months ago
Oestradial HRT & the thyroid, Lenzetto blood tests
I just wondered if low oestradial affects the thyroid? I have been on HRT since March and my level is still only 197 pmol/L. I use 3 sprays of Lenzetto. I wondered if it could be affecting my thyroid function? I don’t have menopause symptoms, I had bottom of range testosterone, but this is now in range
I just wondered if low oestradial affects the thyroid? I have been on HRT since March and my level is still only 197 pmol/L. I use 3 sprays of Lenzetto. I wondered if it could be affecting my thyroid function? I don’t have menopause symptoms, I had bottom of range testosterone, but this is now in range
CornishChick
in
Thyroid UK
9 months ago
No Osteoporosis with Estrogen Patch Therapy
These plots compare results from the Phase-II randomized trial (PATCH) comparing estrogen patch therapy to Lupron ADT. These plots show that Lupron ADT causes bone loss, while estrogen patch therapy has either no bone loss or increased bone mineral density (BMD) over time. Bob
These plots compare results from the Phase-II randomized trial (PATCH) comparing estrogen patch therapy to Lupron ADT. These plots show that Lupron ADT causes bone loss, while estrogen patch therapy has either no bone loss or increased bone mineral density (BMD) over time. Bob
janebob99
in
Prostate Cancer Network
4 months ago
Castration by Estrogen Patch
This plot shows a dramatic decrease in testosterone and PSA after starting estrogen patch therapy, indicating that transdermal estrogen (TDE) therapy effectively castrates men, and with fewer side effects than Lupron ADT.
This plot shows a dramatic decrease in testosterone and PSA after starting estrogen patch therapy, indicating that transdermal estrogen (TDE) therapy effectively castrates men, and with fewer side effects than Lupron ADT.
janebob99
in
Prostate Cancer Network
4 months ago
Anyone have to multi dose transdermal estrogen cream throughout day.
I am absorbing cream quickly and have to multi dose everyday
I am absorbing cream quickly and have to multi dose everyday
Mccrae
in
Menopause and Perimenopause Support
9 months ago
Transdermal estrogen/estradiol as monotherapy for Prostate Cancer
Does anyone know of recent studies, clinical trials or Standard of Care (SoC) protocols using or studying estrogen gels, sprays, ointments or patches as hormone therapy for Prostate Cancer, particularly micrometastatic cancer that has not spread beyond the pelvic region? I am in discussions with my
Does anyone know of recent studies, clinical trials or Standard of Care (SoC) protocols using or studying estrogen gels, sprays, ointments or patches as hormone therapy for Prostate Cancer, particularly micrometastatic cancer that has not spread beyond the pelvic region? I am in discussions with my
Lost_Sheep
in
Prostate Cancer Network
4 months ago
Recent GP visit - Thoughts please!
Hi. I'm 60. Last week I just couldn't function, at my whit's end - again. Did another e-consult. Typed out all my history, including being diagnosed with CFS in 2011 and struggling since then with the list of symptoms. Also included my Medichecks thyroid panel results, which have been ignored by the
Hi. I'm 60. Last week I just couldn't function, at my whit's end - again. Did another e-consult. Typed out all my history, including being diagnosed with CFS in 2011 and struggling since then with the list of symptoms. Also included my Medichecks thyroid panel results, which have been ignored by the
Sleepysparrow
in
Thyroid UK
9 months ago
25th Park Run!
It may not seem like a big deal but it is to me. I couldn't walk til I was 4, have had 3 hip replacements and back surgery. I never ran before I was 69 and now I've done 25 Park runs. I'm feeling very proud of myself. I even knocked a minute off last week's time! It was a glorious morning. I just took
It may not seem like a big deal but it is to me. I couldn't walk til I was 4, have had 3 hip replacements and back surgery. I never ran before I was 69 and now I've done 25 Park runs. I'm feeling very proud of myself. I even knocked a minute off last week's time! It was a glorious morning. I just took
Bruch1
Graduate
in
Couch to 5K
5 months ago
Testosterone and SHBG puzzle ...
Hello all, I am on HRT including testosterone replacement: what do you think of these results? High SHBG, high testosterone but sub-optimal Free Androgen Index, I was told by a menopause doctor that the index should be around 2.5 to be optimal and that is the most important indicator. I was put on a
Hello all, I am on HRT including testosterone replacement: what do you think of these results? High SHBG, high testosterone but sub-optimal Free Androgen Index, I was told by a menopause doctor that the index should be around 2.5 to be optimal and that is the most important indicator. I was put on a
Clara62
in
Menopause and Perimenopause Support
9 months ago
Why do I feel so rundown on ibrance?
Hello, I am a breast cancer survivor, stage 4, her2- , estrogen and progesterone positive.I was on Ibrance and letrozole for around 2 yrs. I was told the pills usually only last 9 months. Almost Depends on the person. Every time I have my labs done my white count and neutrophils were too low.
Hello, I am a breast cancer survivor, stage 4, her2- , estrogen and progesterone positive.I was on Ibrance and letrozole for around 2 yrs. I was told the pills usually only last 9 months. Almost Depends on the person. Every time I have my labs done my white count and neutrophils were too low.
Burtie1
in
SHARE Metastatic Breast Cancer
9 months ago
Frozen DE treatment cycle different to FET with OE
Hello All, I think I’m missing something obvious but can anyone explain why a frozen DE treatment cycle plans the transfer for day 22-24 while both my FETs have been transferred on day 17 ish? I’m anxious because after a mmc with my last FET, I hope this was a sign of receptivity at 17 day mark and
Hello All, I think I’m missing something obvious but can anyone explain why a frozen DE treatment cycle plans the transfer for day 22-24 while both my FETs have been transferred on day 17 ish? I’m anxious because after a mmc with my last FET, I hope this was a sign of receptivity at 17 day mark and
Kitkat10
in
Fertility Network UK
9 months ago
Prostap longer than 6 months?
Hi there. I’m currently on Prostap with Tibilone to manage my stage 4 Endo with adenomyosis, fibroids and an endometrioma. I’m 49 soon so prob perimenopausal. I’ve had a long history of open surgeries, laparatomy etc. so no stranger to surgery. My symptoms are currently very manageable although my
Hi there. I’m currently on Prostap with Tibilone to manage my stage 4 Endo with adenomyosis, fibroids and an endometrioma. I’m 49 soon so prob perimenopausal. I’ve had a long history of open surgeries, laparatomy etc. so no stranger to surgery. My symptoms are currently very manageable although my
Honeybeehappy
in
Endometriosis UK
9 months ago
failed cryo embryo transfer
Hello I am a 44yo woman. My husband and I underwent ivf cycle earlier this year with own egg. We managed to get 9 eggs and 5 embryo. We had to get them genetically tested and after the long process we have 1 frozen embryo of high quality. So we were very excited about the next step and we started
Hello I am a 44yo woman. My husband and I underwent ivf cycle earlier this year with own egg. We managed to get 9 eggs and 5 embryo. We had to get them genetically tested and after the long process we have 1 frozen embryo of high quality. So we were very excited about the next step and we started
Flora_bah
in
Fertility Network UK
9 months ago
cost of Forteo, Tymlos, Evenity, Prolia in USA
after being on HRT for a year my numbers have worsened and I now have osteoporosis in spine and both hips in the -3 range. In addition I need a biopsy for breast lump. Ugh. So I’m faced with choosing a new osteoporosis drug. Besides the side effects they all seem to have, I’m considering the cost as
after being on HRT for a year my numbers have worsened and I now have osteoporosis in spine and both hips in the -3 range. In addition I need a biopsy for breast lump. Ugh. So I’m faced with choosing a new osteoporosis drug. Besides the side effects they all seem to have, I’m considering the cost as
Kimada
in
Osteoporosis Support
9 months ago
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