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Estrogen Replacement Therapy
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Should the dose of Dutasteride be increased?
The plot above shows the residual (nadir) level of DHT in men as a function of the daily Dutasteride dose (mg/day). The DHT nadir numbers shown in this plot are: 23.8 pg/mL for 0.5 mg daily dose; 10.2 pg/mL for 2.5 mg daily dose; and 7.3 pg/mL for 5 mg daily dose. Ref: Clark (2004) [see Table
The plot above shows the residual (nadir) level of DHT in men as a function of the daily Dutasteride dose (mg/day). The DHT nadir numbers shown in this plot are: 23.8 pg/mL for 0.5 mg daily dose; 10.2 pg/mL for 2.5 mg daily dose; and 7.3 pg/mL for 5 mg daily dose. Ref: Clark (2004) [see Table
janebob99
in
Advanced Prostate Cancer
2 months ago
Should the dose of Dutasteride be increased?
The plot above shows the residual (nadir) level of DHT in men as a function of the daily Dutasteride dose (mg/day). The DHT nadir numbers shown in this plot are: 23.8 pg/mL for 0.5 mg daily dose; 10.2 pg/mL for 2.5 mg daily dose; and 7.3 pg/mL for 5 mg daily dose. Ref: Clark (2004) [see Table
The plot above shows the residual (nadir) level of DHT in men as a function of the daily Dutasteride dose (mg/day). The DHT nadir numbers shown in this plot are: 23.8 pg/mL for 0.5 mg daily dose; 10.2 pg/mL for 2.5 mg daily dose; and 7.3 pg/mL for 5 mg daily dose. Ref: Clark (2004) [see Table
janebob99
in
Prostate Cancer Network
2 months ago
Ouch that hurt 🤕
Involved in RTC on Friday, luckily just Bruised Ribs and abdomen.I have spondylitis, damaged discs lumber to sacral, and am awaiting a new hip, which is playing havoc with my TKR, so the added pain really wasn't needed. Hopefully this app will help me get motivated.
Involved in RTC on Friday, luckily just Bruised Ribs and abdomen.I have spondylitis, damaged discs lumber to sacral, and am awaiting a new hip, which is playing havoc with my TKR, so the added pain really wasn't needed. Hopefully this app will help me get motivated.
Eiza
in
My EXI Community
5 months ago
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Zoladex and HRT
I was diagnosed with endo in 2021, it was removed from my abdominal wall but my pain never fully left. Just 4 months later my symptoms returned and the pain was as bad as it was pre-op. Here I am, 19 months later in significant daily pain. I am signed off sick from work for the 3rd week, and it seems
I was diagnosed with endo in 2021, it was removed from my abdominal wall but my pain never fully left. Just 4 months later my symptoms returned and the pain was as bad as it was pre-op. Here I am, 19 months later in significant daily pain. I am signed off sick from work for the 3rd week, and it seems
Ccn2018
in
Endometriosis UK
11 months ago
Secondary Osteoporosis and Metabolic Bone Diseases
https://www.mdpi.com/2077-0383/11/9/2382
Abstract
"Fragility fracture is a worldwide problem and a main cause of disability and impaired quality of life. It is primarily caused by osteoporosis, characterized by impaired bone quantity and or quality. Proper diagnosis of osteoporosis is essential
https://www.mdpi.com/2077-0383/11/9/2382
Abstract
"Fragility fracture is a worldwide problem and a main cause of disability and impaired quality of life. It is primarily caused by osteoporosis, characterized by impaired bone quantity and or quality. Proper diagnosis of osteoporosis is essential
usr2022
in
Bone Health and Osteoporosis UK
11 months ago
Acute Autonomic Crisis
Hi everyone, I hope that you are having as pain free a day as possible. Just an update on my follow up appointment. I had probably one of the worst weeks of my life last week. Weaning off morphine and Citalopram, side effects from the Duloxitine and then such a bad flare up of the burning pain that
Hi everyone, I hope that you are having as pain free a day as possible. Just an update on my follow up appointment. I had probably one of the worst weeks of my life last week. Weaning off morphine and Citalopram, side effects from the Duloxitine and then such a bad flare up of the burning pain that
CecilyParsley
in
Pelvic Pain Support Network
8 months ago
advice/opinions please
over the last few years my TSH has always been outside reference range. The GP has normally said borderline. They have usually been 4.5 and higher but less than 10. Last year in March was 5.3, borderline. Then I had a repeat in June 2022 and it came back as 3.4 no further action which was highly unusual
over the last few years my TSH has always been outside reference range. The GP has normally said borderline. They have usually been 4.5 and higher but less than 10. Last year in March was 5.3, borderline. Then I had a repeat in June 2022 and it came back as 3.4 no further action which was highly unusual
Ozzy77
in
Thyroid UK
11 months ago
What is role of hormonal therapy drug when taken with targeted therapy, eg Piqray or Ibrance?
I’ve been curious about this and wondering if anyone can explain. I want to better understand the role of the hormone therapy eg Faslodex when taken with targeted therapy such as Ibrance. Does it just reduce the amount of estrogen available to the cell and “lightens the load” on the targeted therapy?
I’ve been curious about this and wondering if anyone can explain. I want to better understand the role of the hormone therapy eg Faslodex when taken with targeted therapy such as Ibrance. Does it just reduce the amount of estrogen available to the cell and “lightens the load” on the targeted therapy?
HelenWi
in
SHARE Metastatic Breast Cancer
7 months ago
New 2024 AUA/ASTRO/SUO Guidelines for Salvage Therapy
https://www.auanet.org/guidelines-and-quality/guidelines/salvage-therapy-for-prostate-cancer Not surprising. I think they should recommend adjuvant ADT at a PSA≥0.35 instead of ≥0.7 because I think patients are hoping for curative SRT and not just equivalent survival. https://www.prostatecancer.news
https://www.auanet.org/guidelines-and-quality/guidelines/salvage-therapy-for-prostate-cancer Not surprising. I think they should recommend adjuvant ADT at a PSA≥0.35 instead of ≥0.7 because I think patients are hoping for curative SRT and not just equivalent survival. https://www.prostatecancer.news
Tall_Allen
in
Advanced Prostate Cancer
2 months ago
sailormo
Hi I have pmr trying to reduce my prednisalone from 20mg down to 16mg I've been up and down for afew years, I'm using mycophenolate to help me reduce but I've just had a knee replacement and have lots of aches in my neck shoulders, and thighs.Im feeling a bit depressed do you think the aches will get
Hi I have pmr trying to reduce my prednisalone from 20mg down to 16mg I've been up and down for afew years, I'm using mycophenolate to help me reduce but I've just had a knee replacement and have lots of aches in my neck shoulders, and thighs.Im feeling a bit depressed do you think the aches will get
Sailormo
in
PMRGCAuk
8 months ago
Mitral Valve replacement
Hello all. I'm going in for mitral Valve replacement next week and I still haven't decided whether to have a tissue or mechanical Valve . Has anyone had this surgery? If so can you tell me how you made your decision please? Thanks
Hello all. I'm going in for mitral Valve replacement next week and I still haven't decided whether to have a tissue or mechanical Valve . Has anyone had this surgery? If so can you tell me how you made your decision please? Thanks
Caramilk
in
Heart Valve Voice
8 months ago
RLS Lymphodema and MLD
I have severe RLS and severe PLMD I am currently on 0.5 clonazepam,250 pregabalin and 2mg neupro patches In march i had a knee replacement operation and after this my leg swelled up and I have been diagnosed with lymphodema. I have been prescribed Manual Lymphatic Drainage (MLD) massage therapy I
I have severe RLS and severe PLMD I am currently on 0.5 clonazepam,250 pregabalin and 2mg neupro patches In march i had a knee replacement operation and after this my leg swelled up and I have been diagnosed with lymphodema. I have been prescribed Manual Lymphatic Drainage (MLD) massage therapy I
thorp
in
Restless Legs Syndrome
8 months ago
Update and Feeling Kicked…..
Thank you to everyone who helped me with my last post on this board regarding DNR. I’m relieved to say that my father was released and is possibly back on track to regain some of the weight lost at hospital. Still waiting to hear if it’s lymphoma. As for me I am feeling kinda kicked down this week.
Thank you to everyone who helped me with my last post on this board regarding DNR. I’m relieved to say that my father was released and is possibly back on track to regain some of the weight lost at hospital. Still waiting to hear if it’s lymphoma. As for me I am feeling kinda kicked down this week.
RoseFlowerDew
in
Pernicious Anaemia Society
11 months ago
Bit of a Vent
(Warning: I mention infertility a bit) Hi everyone, My suspected endometriosis has been getting worse and worse, especially after I’ve been put on the implant. I had to go to A&E for the doctor to tell me he didn’t even think morphine would help with my pain… I’ve had to take so many sick days from
(Warning: I mention infertility a bit) Hi everyone, My suspected endometriosis has been getting worse and worse, especially after I’ve been put on the implant. I had to go to A&E for the doctor to tell me he didn’t even think morphine would help with my pain… I’ve had to take so many sick days from
VioletCoffee
in
Endometriosis UK
11 months ago
still here
Hi All I like to try and update my journey so you can see that there are some longer term survivors. I am still on 0 PSA with advanced cancer. My journey is on my bio. I was diagnosed at 47 and now I’m 54 with no progression. My primary treatment was Zytiga and it is still working. I take a concoction
Hi All I like to try and update my journey so you can see that there are some longer term survivors. I am still on 0 PSA with advanced cancer. My journey is on my bio. I was diagnosed at 47 and now I’m 54 with no progression. My primary treatment was Zytiga and it is still working. I take a concoction
Apollo123
in
Advanced Prostate Cancer
4 months ago
Can anyone help
Hi group. Ive been treated for underachieve thyroid for many years, mostly with Levothyroxine (current treatment) and for a brief period years ago Liothyronine (until it was stopped). My background is a healthcare professional and I understand the physiology side of the thyroid gland and associated
Hi group. Ive been treated for underachieve thyroid for many years, mostly with Levothyroxine (current treatment) and for a brief period years ago Liothyronine (until it was stopped). My background is a healthcare professional and I understand the physiology side of the thyroid gland and associated
SOT1512
in
Thyroid UK
6 months ago
New here
Hello everyone. I am 61 next month. 18 months ago I had a hip replacement and I never thought I'd be able to run again, I have been walking and open water swimming for a while and I thought I would have ago at the C25K. Well I am nearly at the end of week 3 and it is going so well.
Hello everyone. I am 61 next month. 18 months ago I had a hip replacement and I never thought I'd be able to run again, I have been walking and open water swimming for a while and I thought I would have ago at the C25K. Well I am nearly at the end of week 3 and it is going so well.
GM11
in
Couch to 5K
8 months ago
Shingrix vaccine for immunosuppressed people aged 50+
I thought I would just post this from the gov.uk website because I have just a bit of struggle convincing our surgery that I was eligible, so maybe other people haven't been invited either. The full list is on chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://assets.publishing.service.gov.uk
I thought I would just post this from the gov.uk website because I have just a bit of struggle convincing our surgery that I was eligible, so maybe other people haven't been invited either. The full list is on chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://assets.publishing.service.gov.uk
Sharitone
in
PMRGCAuk
6 months ago
D3 lowers estrogen in blood!
I bought a kiddie pool so I could lay out and get some sunshine. I grew up on an island and I love the water ... ANY water! So I bought it solely for my enjoyment. Then I come across this article from Fred Hutchinson Cancer Center on how D3 lowers estrogen and this interests me because I recently
I bought a kiddie pool so I could lay out and get some sunshine. I grew up on an island and I love the water ... ANY water! So I bought it solely for my enjoyment. Then I come across this article from Fred Hutchinson Cancer Center on how D3 lowers estrogen and this interests me because I recently
Godbeforme
in
SHARE Metastatic Breast Cancer
11 months ago
PEG Feeding
Hi....my step mum has PSP, she is bed bound and has carers come into her home 3 times a day to help my dad who is her full time carer. She is still able to eat and swallow although this is becoming a lot more difficult and time consuming and can no longer feed herself. The speech therapist spoke to my
Hi....my step mum has PSP, she is bed bound and has carers come into her home 3 times a day to help my dad who is her full time carer. She is still able to eat and swallow although this is becoming a lot more difficult and time consuming and can no longer feed herself. The speech therapist spoke to my
KingKenny73
in
PSP Association
6 months ago
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