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BRCA2- is it the devil or not??
I have been researching about BRCA2 as my husband has this . The more I study about this the scarier it seems, is this wrong. It says that men with BRCA2 are more resistant to treatments and earlier than men that are not. Does this mean my husband most likely will become castrate resistant sooner because
I have been researching about BRCA2 as my husband has this . The more I study about this the scarier it seems, is this wrong. It says that men with BRCA2 are more resistant to treatments and earlier than men that are not. Does this mean my husband most likely will become castrate resistant sooner because
positive-thinking
in
Advanced Prostate Cancer
1 month ago
Third line chemotherapy, Caelyx
so, have started Caelyx every 4 weeks as carboplatin and paclitaxel and Niraparib have stopped working. Surgery to remove peritoneum and resection liver not an option. Does anyone have experience of just Caelyx? Is it effective on its own? Thankyou
so, have started Caelyx every 4 weeks as carboplatin and paclitaxel and Niraparib have stopped working. Surgery to remove peritoneum and resection liver not an option. Does anyone have experience of just Caelyx? Is it effective on its own? Thankyou
Skyeplus
in
My Ovacome
1 month ago
Reaction to docetaxel twice now.
second cycle of docetaxel and the same reaction. Pelvic pain, flushing, muzzy head and head ache. Great response from the team again and feeling better pretty quickly. Last time they tried again and it went through okay. Had meds to mitigate but not prevented a reaction. They aren’t go to try the infusion
second cycle of docetaxel and the same reaction. Pelvic pain, flushing, muzzy head and head ache. Great response from the team again and feeling better pretty quickly. Last time they tried again and it went through okay. Had meds to mitigate but not prevented a reaction. They aren’t go to try the infusion
FortyWinks
in
Advanced Prostate Cancer
1 month ago
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Lutetium at earlier stage, clinical trial is enrolling
The second trial provides men with metastatic prostate cancer access to prostate-specific membrane antigen (PSMA)-targeted therapy prior to chemotherapy. Currently, PSMA-targeted therapy is only available after chemotherapy. However, phase III clinical trials have shown that PSMA-targeted therapies are
The second trial provides men with metastatic prostate cancer access to prostate-specific membrane antigen (PSMA)-targeted therapy prior to chemotherapy. Currently, PSMA-targeted therapy is only available after chemotherapy. However, phase III clinical trials have shown that PSMA-targeted therapies are
Maxone73
in
Advanced Prostate Cancer
1 month ago
Starting clinical trial of AVR-766
Today I start a clinical trial for ARV-766, an AR degrader. I'm coming in at phase 2, and they are only accepting men who have one of 4 point mutations in the AR - I have two. I've been randomized to 300 mg pill, once a day. The other dose is 100mg. I've failed ADT, chemo. Keytruda & Pluvicto. Hoping
Today I start a clinical trial for ARV-766, an AR degrader. I'm coming in at phase 2, and they are only accepting men who have one of 4 point mutations in the AR - I have two. I've been randomized to 300 mg pill, once a day. The other dose is 100mg. I've failed ADT, chemo. Keytruda & Pluvicto. Hoping
rsgdmd
in
Advanced Prostate Cancer
2 months ago
After Zytiga-Xtandi Fail!
Following up on a post by "Chris52981", after Zytiga and Xtandi fail, if chemo is the next treatment, how much time do we really buy? Is it Month's? Weeks? or Years?
Following up on a post by "Chris52981", after Zytiga and Xtandi fail, if chemo is the next treatment, how much time do we really buy? Is it Month's? Weeks? or Years?
TommyCarz2
in
Advanced Prostate Cancer
2 months ago
Recent HF diagnosis
Hi, I was diagnosed with heart failure a couple of months ago when I woke up one morning struggling for breath with fluid in my lungs, having had virtually no previous symptoms. Looking back, maybe I was a bit short of breath over the last few months but did a sprint-distance triathlon 6 months ago so
Hi, I was diagnosed with heart failure a couple of months ago when I woke up one morning struggling for breath with fluid in my lungs, having had virtually no previous symptoms. Looking back, maybe I was a bit short of breath over the last few months but did a sprint-distance triathlon 6 months ago so
izzibear
in
British Heart Foundation
2 months ago
PSA after chemo # 4
Hi My husbands last chemo was # 3 and PSA was 0.14, he just got the results from Chemo # 4 and it was at 0.12. This is the slowest decline if you look in the profile Iisted all his PSA results. Should we be worried that this last one barely moved ? Or is this slower decline good news? Thanks for any
Hi My husbands last chemo was # 3 and PSA was 0.14, he just got the results from Chemo # 4 and it was at 0.12. This is the slowest decline if you look in the profile Iisted all his PSA results. Should we be worried that this last one barely moved ? Or is this slower decline good news? Thanks for any
positive-thinking
in
Advanced Prostate Cancer
2 months ago
I need urgent help for my uncle.
My uncle who resides in France and is a holder of a French citizenship, has been diagnosed with terminal prostatic cancer. He had treated this condition in the past but it ultimately came back, but this time around doctors (including a specialist in Marseille) made him know that his condition was incurable
My uncle who resides in France and is a holder of a French citizenship, has been diagnosed with terminal prostatic cancer. He had treated this condition in the past but it ultimately came back, but this time around doctors (including a specialist in Marseille) made him know that his condition was incurable
Admhdu
in
Advanced Prostate Cancer
2 months ago
I need urgent help for my uncle
My uncle who resides in France and is a holder of a French citizenship, has been diagnosed with terminal prostatic cancer. He had treated this condition in the past but it ultimately came back, but this time around doctors (including a specialist in Marseille) made him know that his condition was incurable
My uncle who resides in France and is a holder of a French citizenship, has been diagnosed with terminal prostatic cancer. He had treated this condition in the past but it ultimately came back, but this time around doctors (including a specialist in Marseille) made him know that his condition was incurable
Admhdu
in
Advanced Prostate Cancer
2 months ago
Painful Sex
Hi Ladies If you had painful sex problems would you mind reading this and sharing if you experienced anything similar and if so what action was taken? My fear is that maybe the sex pain is an indication of a more worrying problem eg bowel adhesions or even recurrence. Thanks. On Friday my boyfriend
Hi Ladies If you had painful sex problems would you mind reading this and sharing if you experienced anything similar and if so what action was taken? My fear is that maybe the sex pain is an indication of a more worrying problem eg bowel adhesions or even recurrence. Thanks. On Friday my boyfriend
Emcee71
in
My Ovacome
2 months ago
chemo
has anyone who failed xtandi and zytiga have good outcome with chemo- does it completely eliminate the cancer or do you still have to take things after - how does it work when it stops - also can you take it in smaller doses?
has anyone who failed xtandi and zytiga have good outcome with chemo- does it completely eliminate the cancer or do you still have to take things after - how does it work when it stops - also can you take it in smaller doses?
Chris52981
in
Advanced Prostate Cancer
2 months ago
Treatment plan / second opinions
hi everyone! first time poster - probably won’t be my last !! Just at the start of this journey, mums getting her Treatment Plan for first line treatment on Friday and I’d love any thoughts on what questions we should be asking? And would this be the stage for getting a second opinion (and is it
hi everyone! first time poster - probably won’t be my last !! Just at the start of this journey, mums getting her Treatment Plan for first line treatment on Friday and I’d love any thoughts on what questions we should be asking? And would this be the stage for getting a second opinion (and is it
georgiageorgia182
in
My Ovacome
2 months ago
what have I joined?
I have a Brian tumour had the surgery now going to treatment radio chemo etc… Been told exercise is good Any advice on how much? Or little? any tips on best diets
I have a Brian tumour had the surgery now going to treatment radio chemo etc… Been told exercise is good Any advice on how much? Or little? any tips on best diets
Ppmoorman65
in
Glioblastoma Support
2 months ago
Rechallenge Docetaxel - more than 6?
My husband has just finished his rechallenge of Docetaxel on 2/29x He did 6 rounds and while things are shrinking it didn’t have the significant change I think they wanted. So his MO at Mayo now wants him to do more chemo until he can no longer tolerate. It’s the standard 75g and my wrestle is why
My husband has just finished his rechallenge of Docetaxel on 2/29x He did 6 rounds and while things are shrinking it didn’t have the significant change I think they wanted. So his MO at Mayo now wants him to do more chemo until he can no longer tolerate. It’s the standard 75g and my wrestle is why
mdiaz76
in
Advanced Prostate Cancer
2 months ago
Discoloured teeth
Has anyone had trouble with discolouration of their teeth? I have been cleaning regularly but was told to rinse with corsodyl which I think is the cause of the problem. Of course, I haven't been to a hygienist in ages as still having chemotherapy. I know this is a cosmetic thing but it is really getting
Has anyone had trouble with discolouration of their teeth? I have been cleaning regularly but was told to rinse with corsodyl which I think is the cause of the problem. Of course, I haven't been to a hygienist in ages as still having chemotherapy. I know this is a cosmetic thing but it is really getting
Swimbuddy
in
My Ovacome
2 months ago
Confused
UPDATE: April 5, 2024 Yesterday was very disappointing as my husbands PSA increased again by 183 points, last month his PSA was 1546 and now it is 1730. All his other CBC results were good. His Alkaline Phosphatase increased 6 points, last month 127 and now 133 but still in range of 40-150. Questioned
UPDATE: April 5, 2024 Yesterday was very disappointing as my husbands PSA increased again by 183 points, last month his PSA was 1546 and now it is 1730. All his other CBC results were good. His Alkaline Phosphatase increased 6 points, last month 127 and now 133 but still in range of 40-150. Questioned
MsHope
in
Advanced Prostate Cancer
2 months ago
CLL survival times ARE improving, thanks to BTK and BCL-2 inhibitors
Many of us were shocked after our CLL/SLL diagnosis when we googled for survival times. [u]Hopefully[/u] we subsequently read that search engine information from Google, Bing, etc., is way out of date, due to the fact that with CLL being a chronic disease, the relatively long survival times with this
Many of us were shocked after our CLL/SLL diagnosis when we googled for survival times. [u]Hopefully[/u] we subsequently read that search engine information from Google, Bing, etc., is way out of date, due to the fact that with CLL being a chronic disease, the relatively long survival times with this
AussieNeil
Administrator
in
CLL Support
2 months ago
Living day by day
I have small Cell lung cancer received chemo and radiation ended treatment March 2023 all clear, restaged cat scan in Sept of 2023 and it was back started immunotherapy opdiva starting end of Sept 2023 the tumor didn't leave but wasn't spreading. In jan was diagnosed with a numerological issue and can't
I have small Cell lung cancer received chemo and radiation ended treatment March 2023 all clear, restaged cat scan in Sept of 2023 and it was back started immunotherapy opdiva starting end of Sept 2023 the tumor didn't leave but wasn't spreading. In jan was diagnosed with a numerological issue and can't
Watermelon67
in
The Roy Castle Lung Cancer Foundation
2 months ago
Bone pain, what next?
For over 2 years my scans show no radiographic progression despite a rising PSA, now at 43. However I am now experiencing periodic bone pain in the left hip area, mainly when I climb stairs. Tolerable but a worrying development. Even with lack of visible progression I think we need to change something
For over 2 years my scans show no radiographic progression despite a rising PSA, now at 43. However I am now experiencing periodic bone pain in the left hip area, mainly when I climb stairs. Tolerable but a worrying development. Even with lack of visible progression I think we need to change something
Ian99
in
Advanced Prostate Cancer
2 months ago
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