Update and question about Olaparib

[Iwasborntodothis]

Its my 60th birthday today! Glad to still be here!

CT scan was stable but CA15 continues to rise on Trodelvy. CA15 is an important indicator for me. This info plus a comprehensive new Gardian DNA blood genetic test showed us some new options based on my mutations/bio markers (I am an architect so firgive me if I get this wrong) posting in case anyone needs info for themselves later:

ESR1 suggest: Elacestrant (option) and Letrozole(already had)

ATM suggest: Olaparib or Talazoparib

So, when I finish this round of Trodelvy and if insurance approves, I will start Olaparib which is a pill and take a break from IV chemo. I suspect we will give it 8 weeks and if it doesn't work, I have been pre-approved for Enhertu. I'm actually fairly excited to have the freedom of a pill so I can get up to our cabin and out of the heat for a longer period of time.

Lots of info I know but would love to know if anyone has heard of or had experience with Olaparib.

[MBorne1]

60!!! What an amazing year! I’m so happy to hear you’re going to get a break from the pokes for a bit. Praying for good results for you. And I’m also praying you’ll get to see the beauty of the world when you visit your cabin!

[Iwasborntodothis in reply to MBorne1]

Thank you!

[Shafight]

I just love your on line name, I was born to do this. We were all born to be warriors!

[Pbsoup]

Welcome to the club of being 60! I think it's the new 40 (or something like that.) I just think how the hell did I get to be so old!

What form of architecture do you practice? I am architect-adjacent as I advise my brother's foundation who supports social impact design, and work as fundraising and strategy consultant to a terrific Mumbai practice working alongside disenfranchised communities to reimagine their built environments. (thus my frequent trips to India)

I haven't had experience with either drug. I was on Elascatrant for a hot minute as I have the ESRI mutation but it didn't work for me. I am now on Affintor which seems to be working. Will be interested to hear how it goes for you. I have also heard great things about Enhertu...

There are so many positive stories out there these days. None of this is fun, but at least there is hope.

[Aprilfoolz1]

Happy birthday !! I'm also born in 1964 I have not been on lymparza but have heard good things about it . I know a woman on another mbc message board who has been stable on it for a couple of years .

[Pups2Cute]

Happy birthday wishes!!!