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Temgesic/Buprenorphine
Jelbea and Shumbah have both posted recently about Temgesic versus Buprenorphine and the different half life of these 2 medicines.Both have Buprenorphine hydrochloride as the active ingredient BUT Temgesic has a much shorter half life. This means it will have to be taken every 6 to 8 hours throughout
Jelbea and Shumbah have both posted recently about Temgesic versus Buprenorphine and the different half life of these 2 medicines.Both have Buprenorphine hydrochloride as the active ingredient BUT Temgesic has a much shorter half life. This means it will have to be taken every 6 to 8 hours throughout
Joolsg
in
Restless Legs Syndrome
11 months ago
Indomethacin - resenisitize to Enza
In a preclinical study indo seems to resensitize to Enza by blocking CRXR7 thus indirectly AR-V7. The trial was started in 2018, results should be known in July 2023. Does anybody know anything from that trial? I just rechallenged with Enza bringing PSA down from 7 to 0.5, if adding cheap indo prevents
In a preclinical study indo seems to resensitize to Enza by blocking CRXR7 thus indirectly AR-V7. The trial was started in 2018, results should be known in July 2023. Does anybody know anything from that trial? I just rechallenged with Enza bringing PSA down from 7 to 0.5, if adding cheap indo prevents
Hidden
in
Fight Prostate Cancer
9 months ago
Looking for guidance on RLS and Parkinson's Management
Good Morning, Read this forum regularly... thank you for sharing ... Looking to learn more about RLS and Parkinson's, especially from persons with these two conditions particularly their medication management. My husband has both conditions, RLS since mid 2000s, Parkinson's since 2018. And we are
Good Morning, Read this forum regularly... thank you for sharing ... Looking to learn more about RLS and Parkinson's, especially from persons with these two conditions particularly their medication management. My husband has both conditions, RLS since mid 2000s, Parkinson's since 2018. And we are
gardening57
in
Restless Legs Syndrome
10 months ago
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Chronic constipation
hi so I have been suffering with severe chronic constipation soft stools for almost 3 years, they have done testings and ruled out nothing. I always feel it in my rectum and they did a defecography on me last week and found an intra-anal intussusception and a 2.5 cm Rectocele. I am confused on this.
hi so I have been suffering with severe chronic constipation soft stools for almost 3 years, they have done testings and ruled out nothing. I always feel it in my rectum and they did a defecography on me last week and found an intra-anal intussusception and a 2.5 cm Rectocele. I am confused on this.
Liv12b
in
IBS Network
10 months ago
Medically induced zombie looking for help!
Is anyone else on Pregabalin and if so, how do you cope with 'zombiefying' side effects? I spend most of my working day on a computer and sometimes I feel like I can barely keep my eyes open. I'm also on Celecoxib and Topiramate.
Is anyone else on Pregabalin and if so, how do you cope with 'zombiefying' side effects? I spend most of my working day on a computer and sometimes I feel like I can barely keep my eyes open. I'm also on Celecoxib and Topiramate.
Fibro_warrior
in
Fibromyalgia Action UK
11 months ago
Uti and vaginal irritation
.I suffer from recurrant uti .I also have on going vaginal itching on and off .does anyone have this prob and could uti cause irritation. Would appreciate any information thank you and have a nice day 🥲
.I suffer from recurrant uti .I also have on going vaginal itching on and off .does anyone have this prob and could uti cause irritation. Would appreciate any information thank you and have a nice day 🥲
Dextersam10
in
Pelvic Pain Support Network
11 months ago
Neupro Patch
I saw a consultant in the UK a month or so ago and explained that my transition from Mirapexin to Pregabalin was not going well. At that time, I was taking 150mg Pregabalin and 4 x 0.088 Mirapexin and that at that level i was getting some relief but that any reduction from that in the Mirapexin left
I saw a consultant in the UK a month or so ago and explained that my transition from Mirapexin to Pregabalin was not going well. At that time, I was taking 150mg Pregabalin and 4 x 0.088 Mirapexin and that at that level i was getting some relief but that any reduction from that in the Mirapexin left
Ced60
in
Restless Legs Syndrome
11 months ago
Rutin / Senolytics
New paper below [1]. In 1995, Edward Giovannucci was responsible for triggering the PCa lycopene craze. "Of 46 vegetables and fruits or related products, four were significantly associated with lower prostate cancer risk; of the four--tomato sauce, tomatoes, and pizza, but not strawberries--were
New paper below [1]. In 1995, Edward Giovannucci was responsible for triggering the PCa lycopene craze. "Of 46 vegetables and fruits or related products, four were significantly associated with lower prostate cancer risk; of the four--tomato sauce, tomatoes, and pizza, but not strawberries--were
pca2004
in
Fight Prostate Cancer
10 months ago
Dual ARi in mCRPCa - Antonarakis = 'Combo of 2 AR-directed agents should not be utilized in clinical practice at this time', MedPage 7/20/23
Posted without comment for the SOC crowd. [i]
Emmanuel Antonarakis, MD, on Dual Androgen Receptor Inhibition in Metastatic Castration-Resistant Prostate Cancer– 'Combination of two androgen-directed agents should not be utilized in clinical practice at this time', MedPage Today, ASCO > Prostate Cancer
Posted without comment for the SOC crowd. [i]
Emmanuel Antonarakis, MD, on Dual Androgen Receptor Inhibition in Metastatic Castration-Resistant Prostate Cancer– 'Combination of two androgen-directed agents should not be utilized in clinical practice at this time', MedPage Today, ASCO > Prostate Cancer
cujoe
in
Fight Prostate Cancer
10 months ago
Petrified !!!!
Hello , I am 52 yrs old and this will be my first colonoscopy . For about a year I have has haemorrhoids on and off very itchy and sore bottom that goes with it. Felt the lump/s when I have had the attacks. No lumps present now. Have had some constipation lately and have seen a little blood when
Hello , I am 52 yrs old and this will be my first colonoscopy . For about a year I have has haemorrhoids on and off very itchy and sore bottom that goes with it. Felt the lump/s when I have had the attacks. No lumps present now. Have had some constipation lately and have seen a little blood when
Hidden
in
IBS Network
10 months ago
Review of Top 10 Prescribed Drugs and Their Interaction with Dental Treatment
The dentist must recognize that these medications may interact with
dental
treatment
. This article reviews the top 10 prescribed drugs as listed in the IMS Institute national prescription audit in January 2015 and reviews the interactions between these medications and
dental
treatment
.
The dentist must recognize that these medications may interact with
dental
treatment
. This article reviews the top 10 prescribed drugs as listed in the IMS Institute national prescription audit in January 2015 and reviews the interactions between these medications and
dental
treatment
.
helvella
Thyroid UK
in
Thyroid UK
2 years ago
Colestyramine
I have recently had a colonoscopy which resulted in all biopsies being clear. So have had a diagnosis of ibs d and possible Bile Acid Malabsorption. My consultant started me on 1x 4g sachet once a day for a week and increased to two sachets a day for a week.But I’m still having very loose, frequent stools
I have recently had a colonoscopy which resulted in all biopsies being clear. So have had a diagnosis of ibs d and possible Bile Acid Malabsorption. My consultant started me on 1x 4g sachet once a day for a week and increased to two sachets a day for a week.But I’m still having very loose, frequent stools
Yoga82
in
IBS Network
10 months ago
Treating symptoms causes more issues.
So if I use a medication to fix a symptom, I can end up worse off. Recently I took mebeverine to slow motility as I pass a lot of bowel movements a day. It was to help with morning cramps. I just felt sore, constipated and couldn’t eat as normal after. So the mebeverine fixes one problem and causes
So if I use a medication to fix a symptom, I can end up worse off. Recently I took mebeverine to slow motility as I pass a lot of bowel movements a day. It was to help with morning cramps. I just felt sore, constipated and couldn’t eat as normal after. So the mebeverine fixes one problem and causes
Mumof31983
in
IBS Network
11 months ago
Dental work?
To old &sick to deal with yet another health issue & now the need of major
dental
work. More anxiety & depression & researching yet another
treatment
&side effects, efficacy &on&on.
To old &sick to deal with yet another health issue & now the need of major
dental
work. More anxiety & depression & researching yet another
treatment
&side effects, efficacy &on&on.
MyCheesecake
in
Osteoporosis Support
11 months ago
Bloods
Can anyone explain what these mean pleaseFull blood count Rouleaux + Lymphocytosis persists FILM REFERRED TO CONSULTANT HAEMATOLOGIST note raised esr and leukocytosis? underlying cause
Can anyone explain what these mean pleaseFull blood count Rouleaux + Lymphocytosis persists FILM REFERRED TO CONSULTANT HAEMATOLOGIST note raised esr and leukocytosis? underlying cause
pettyt65
in
Thyroid UK
11 months ago
Switching to home hemodialysis
I have been on peritoneal dialysis using a cycler, which has been wonderful, for two years. Unfortunately my clearance has been falling over the last four months and treatment increase in the amount of dextrose has caused me to gain nearly 30 lb. My clinic has me scheduled to begin training for home
I have been on peritoneal dialysis using a cycler, which has been wonderful, for two years. Unfortunately my clearance has been falling over the last four months and treatment increase in the amount of dextrose has caused me to gain nearly 30 lb. My clinic has me scheduled to begin training for home
platypusak
in
Kidney Dialysis
1 year ago
My reaction to Crestor & Nubeqa combo. I need to make some adjustments. This study says simvastatin is best against APC. Your thoughts?
Based on these studies, do you think it's best to use simvastatin as your choice of statins? I'm using Crestor 5 mg plus 5mg Zetia and my ldl has gone down to a level, which puts me at risk of infection. Plus, my brain isnt functioning nearly as well as it used to. My current ldl is 27. This probably
Based on these studies, do you think it's best to use simvastatin as your choice of statins? I'm using Crestor 5 mg plus 5mg Zetia and my ldl has gone down to a level, which puts me at risk of infection. Plus, my brain isnt functioning nearly as well as it used to. My current ldl is 27. This probably
GeorgeGlass
in
Fight Prostate Cancer
11 months ago
Elevated creatinine from tacrolimus?
I am 19 months out from my kidney transplant from a deceased donor. Was doing well and my creatinine was actually within the normal range at about a year post transplant. However, since then my creatinine has been creeping up and now is 1.74. Have tried lowering my protein intake, and more hydration
I am 19 months out from my kidney transplant from a deceased donor. Was doing well and my creatinine was actually within the normal range at about a year post transplant. However, since then my creatinine has been creeping up and now is 1.74. Have tried lowering my protein intake, and more hydration
Hawk12
in
Kidney Transplant Patient Support
1 year ago
Oral thrush and throat swabs
Hi gp tells me that I have oral thrush but the throat swabs keep coming back negative for oral thrush. ent consultant had a look but said no oral thrush.. for some strange reason nystatin seems to help a little bit has anyone else had a negative throat swab for oral candida and did fluconazole cure
Hi gp tells me that I have oral thrush but the throat swabs keep coming back negative for oral thrush. ent consultant had a look but said no oral thrush.. for some strange reason nystatin seems to help a little bit has anyone else had a negative throat swab for oral candida and did fluconazole cure
lindyloo2018
in
NRAS
1 year ago
17 hour flight
I have been invited to a wedding in Louisiana later this year. My RLS is still problematic but manageable at home with Buprenorphine and Pregabalin and walking around / standing up. I am doubtful about the 17 hours flights. I can't ever remember going that long without several attacks of RLS. I've
I have been invited to a wedding in Louisiana later this year. My RLS is still problematic but manageable at home with Buprenorphine and Pregabalin and walking around / standing up. I am doubtful about the 17 hours flights. I can't ever remember going that long without several attacks of RLS. I've
Biscuitface
in
Restless Legs Syndrome
1 year ago
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