Jelbea and Shumbah have both posted recently about Temgesic versus Buprenorphine and the different half life of these 2 medicines.Both have Buprenorphine hydrochloride as the active ingredient BUT Temgesic has a much shorter half life.
This means it will have to be taken every 6 to 8 hours throughout the day to avoid mini opioid withdrawals. The main symptom of opioid withdrawals is SEVERE RLS.
Buprenorphine has a half life of 24 hours so only needs to be taken at night and will cover daytime RLS and not cause opioid withdrawals.
Yet again, the lack of knowledge amongst doctors about RLS and the pharmakinetic properties of drugs is causing unnecessary suffering.
Temgesic is NOT licensed in the UK for RLS, nor is Buprenorphine so there should be no reason for doctors to prescribe Temgesic over Buprenorphine.
I attach relevant articles which might help you persuade your doctors to prescribe plain Buprenorphine over Temgesic.
Temgesic does NOT appear to be available in the USA. I've asked Dr Berkowski about it and he only knows of Buprenorphine buccal, pills or patch.
On behalf of those struggling on Temgesic, I feel your rage and frustration.
Aaaaaaaaaaagh!!!!!
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medicines.org.uk/emc/produc...
Amendment
I've done a LOT of further research on this subject. Many articles mention Temgesic has a shorter half life. HOW, I've looked at all the medication leaflets online and the pharmakinetic properties as listed in research papers.
Temgesic has EXACTLY the same pharmakinetic properties as Buprenorphine. It comes in 0.2mg pills, so the only difference might be that the lower dose is not as effective as Buprenorphine, which starts at 0.4mg pills.
I can find nothing to show Temgesic is any different to Buprenorphine.
Different brands may produce different results.