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Dapagliflozin / Metformin
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Neuroprotective effect of rapamycin against Parkinson's disease in mice - 2018 https://pubmed.ncbi.nlm.nih.gov/30693687/
Conclusions: Rapamycin inhibits the activation of mTOR pathway, which contributes to protect against the loss of dopaminergic neurons and provide behavioral improvements in mice with Parkinson's disease. These results are partially related to the ability of rapamycin in inducing autophagy and reducing
Conclusions: Rapamycin inhibits the activation of mTOR pathway, which contributes to protect against the loss of dopaminergic neurons and provide behavioral improvements in mice with Parkinson's disease. These results are partially related to the ability of rapamycin in inducing autophagy and reducing
Bolt_Upright
in
Cure Parkinson's
3 years ago
Methotrexate? Is it too soon to go onto this drug
Hi everyone, I was diagnosed with PMR in August 2020 and have found this forum invaluable over the past 13 months. This is my first post as so far I have always found the answer to my questions somewhere on the site. However on this occasion I would really appreciate some advice. I’ve just updated
Hi everyone, I was diagnosed with PMR in August 2020 and have found this forum invaluable over the past 13 months. This is my first post as so far I have always found the answer to my questions somewhere on the site. However on this occasion I would really appreciate some advice. I’ve just updated
Tiggy70
in
PMRGCAuk
3 years ago
To take metformin or not?
Hi all 👋🏻 Think I’m having a last minute wobble but wanting to get some other opinions. I have PCOS and in the past have had 60+ day cycles. I pushed the clinic to give me metformin which (no surprise) made me feel crap so when I got covid in august I stopped taking it after only 3 weeks and never
Hi all 👋🏻 Think I’m having a last minute wobble but wanting to get some other opinions. I have PCOS and in the past have had 60+ day cycles. I pushed the clinic to give me metformin which (no surprise) made me feel crap so when I got covid in august I stopped taking it after only 3 weeks and never
RecipIVF
in
Fertility Network UK
3 years ago
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Looking for anyone else with the RAD51B mutation with mets to liver.
New here but not new to Prostate cancer. I'm writing for my dad that was first diagnosed with prostate cancer in October 2010 via digital exam when PSA was only 2.8. Had robotic surgery Feb. 2011 - post Gleason Score 7 (4+3) minor component pattern 5, margins clean and no Seminal Vesicle involvement
New here but not new to Prostate cancer. I'm writing for my dad that was first diagnosed with prostate cancer in October 2010 via digital exam when PSA was only 2.8. Had robotic surgery Feb. 2011 - post Gleason Score 7 (4+3) minor component pattern 5, margins clean and no Seminal Vesicle involvement
Dadslove
in
Advanced Prostate Cancer
3 years ago
New to the site
Hi, I'm new to this site although registered for the CLL site. I'm a 72 yr old male with a history of high blood glucose and on metformin 500mg x2. In May of 2020 I began treatment for CLL which included both infusion (obinutuzumab) and oral (venetoclax) meds. Just after starting the infusions which
Hi, I'm new to this site although registered for the CLL site. I'm a 72 yr old male with a history of high blood glucose and on metformin 500mg x2. In May of 2020 I began treatment for CLL which included both infusion (obinutuzumab) and oral (venetoclax) meds. Just after starting the infusions which
marrix
in
Diabetes Support
3 years ago
Side affects of Spironolactone and Metformin
PCOS Spironolactone and metformin Pills…. I was diagnosed as have insulin resistant PCOS three months ago. I went to the docs due to excessive groin sweating being very hairy and headaches…. My blood showed high testosterone and something else sorry can’t remember so this with the symptoms led to
PCOS Spironolactone and metformin Pills…. I was diagnosed as have insulin resistant PCOS three months ago. I went to the docs due to excessive groin sweating being very hairy and headaches…. My blood showed high testosterone and something else sorry can’t remember so this with the symptoms led to
New-start2021
in
PCOS UK (Verity)
3 years ago
Metformin
I am on the maximum dose of Metformin. I find the laxative, breathing and shivering side-effects to be debilitating. My diabetes nurse is unwilling to change to an alternative so I have booked to see my GP. She said I wasn't drinking enough water but I am drinking 3 pints a day. I am just flushing it
I am on the maximum dose of Metformin. I find the laxative, breathing and shivering side-effects to be debilitating. My diabetes nurse is unwilling to change to an alternative so I have booked to see my GP. She said I wasn't drinking enough water but I am drinking 3 pints a day. I am just flushing it
bionicjohn
in
Diabetes & Hypertension Help Society
3 years ago
Dapavlifozin
I'm on dapagliflozin for heart failure and I'm having pins and needles in legs and feeling very dizzy, iv now been took off them, can I go on another drug to help me. Lynn
I'm on dapagliflozin for heart failure and I'm having pins and needles in legs and feeling very dizzy, iv now been took off them, can I go on another drug to help me. Lynn
Bigsock1234
in
British Heart Foundation
3 years ago
New member looking for advice
EDIT 2: Found New blood test where TSH is now up to 5.63 (only 3 months distance from previous test which showed 4.5!) FT4 was 16 however which is within range. But also showed MCH, MCHC and MCV borderline which could be related to iron deficient anaemia apparently. Test pic below. EDIT: oh wow! This
EDIT 2: Found New blood test where TSH is now up to 5.63 (only 3 months distance from previous test which showed 4.5!) FT4 was 16 however which is within range. But also showed MCH, MCHC and MCV borderline which could be related to iron deficient anaemia apparently. Test pic below. EDIT: oh wow! This
OudMood
in
Thyroid UK
3 years ago
Metformin Recall
Rosemont Pharmaceuticals is recalling some batches of Metformin. I am posting it as it is something easily missed.
Please see:
https://www.gov.uk/drug-device-alerts/class-2-medicines-recall-rosemont-pharmaceuticals-limited-metformin-hydrochloride-500mg-slash-5ml-oral-solution-pl-00427-slash
Rosemont Pharmaceuticals is recalling some batches of Metformin. I am posting it as it is something easily missed.
Please see:
https://www.gov.uk/drug-device-alerts/class-2-medicines-recall-rosemont-pharmaceuticals-limited-metformin-hydrochloride-500mg-slash-5ml-oral-solution-pl-00427-slash
MichaelJH
in
Diabetes Research & Wellness Foundation
3 years ago
Metformin Recall
I know a number of you here have Type II diabetes. Rosemont Pharmaceuticals are recalling some batches of Metformin. I am posting it as it is something easily missed. https://www.gov.uk/drug-device-alerts/class-2-medicines-recall-rosemont-pharmaceuticals-limited-metformin-hydrochloride-500mg-slash-5ml-oral-solution-pl
I know a number of you here have Type II diabetes. Rosemont Pharmaceuticals are recalling some batches of Metformin. I am posting it as it is something easily missed. https://www.gov.uk/drug-device-alerts/class-2-medicines-recall-rosemont-pharmaceuticals-limited-metformin-hydrochloride-500mg-slash-5ml-oral-solution-pl
MichaelJH
Heart Star
in
British Heart Foundation
3 years ago
Class 2 Medicines Recall: Rosemont Pharmaceuticals Limited, Metformin Hydrochloride 500mg/5ml Oral Solution, PL 00427/0139, EL (21)A/20
I get regular alerts for medicine recalls. Most are obscure products used only in hospital or highly specialist areas. However, when I see one that might be of more general applicability, that members might really be taking, I will post. [i]
Class 2 Medicines Recall: Rosemont Pharmaceuticals Limited
I get regular alerts for medicine recalls. Most are obscure products used only in hospital or highly specialist areas. However, when I see one that might be of more general applicability, that members might really be taking, I will post. [i]
Class 2 Medicines Recall: Rosemont Pharmaceuticals Limited
helvella
Thyroid UK
in
Thyroid UK
3 years ago
Buprenorphine/ Subutex,, Temgesic,CBD, THC , Traumeel injections
I can’t not emphasis this enough Anyone starting Buprenorphine / Subutex Or the micro dose version Temgesic. You will not get this advice from your doctors but I urge you to start in this manor. Buy a pill cutter and nightly cut you sublingual tablet into about 8 /10 tiny little crumbs. These medications
I can’t not emphasis this enough Anyone starting Buprenorphine / Subutex Or the micro dose version Temgesic. You will not get this advice from your doctors but I urge you to start in this manor. Buy a pill cutter and nightly cut you sublingual tablet into about 8 /10 tiny little crumbs. These medications
Shumbah
in
Restless Legs Syndrome
3 years ago
Low blood pressure
Hi👋🏻 Has anyone had low blood pressure before a FET and had a successful outcome? This hasn’t happened before but I am wondering if it’s the mix of supplements I’m taking: Metformin Pre natal vitamins Ovulation support supplements Magnesium Calc Fluor Cod liver oil Probiotic Also want to try aspirin
Hi👋🏻 Has anyone had low blood pressure before a FET and had a successful outcome? This hasn’t happened before but I am wondering if it’s the mix of supplements I’m taking: Metformin Pre natal vitamins Ovulation support supplements Magnesium Calc Fluor Cod liver oil Probiotic Also want to try aspirin
RecipIVF
in
Fertility Network UK
3 years ago
Metformin
https://www.livemint.com/science/health/the-toxic-drug-impurity-imperilling-indians-11629044573070.html
https://www.livemint.com/science/health/the-toxic-drug-impurity-imperilling-indians-11629044573070.html
vyas123
in
Diabetes & Hypertension Help Society
3 years ago
A breakthrough-like effect of metformin reduces peripheral resistance to triiodothyronine in euthyroid, non-insulin-resistant, T2 diabetes
My main aim here is to identify to anyone interested that metformin appears to have an impact of T3 levels. Whether the hypotheses of the paper make any sense of that observation is, I fear, rather more questionable. (Though I accept is was very much acknowledged to be a pilot study.) [i]
A breakthrough-like
My main aim here is to identify to anyone interested that metformin appears to have an impact of T3 levels. Whether the hypotheses of the paper make any sense of that observation is, I fear, rather more questionable. (Though I accept is was very much acknowledged to be a pilot study.) [i]
A breakthrough-like
helvella
Thyroid UK
in
Thyroid UK
3 years ago
Is this 1984?
In addition to 11 mg of steroids I am also now having to take 1 1/2 gms of Metformin and 4 insulin injections per day. I am only socialising outside with friends who are doubly vaccinated and I have not been to a restaurant yet. I have no current plans to visit a cinema or theatre yet and the club I
In addition to 11 mg of steroids I am also now having to take 1 1/2 gms of Metformin and 4 insulin injections per day. I am only socialising outside with friends who are doubly vaccinated and I have not been to a restaurant yet. I have no current plans to visit a cinema or theatre yet and the club I
butterflyfarm
in
PMRGCAuk
3 years ago
PCOS and miscarriage
*trigger alert - this post contains discussion of miscarriage - just a heads up* Hi everyone. I’ve never done anything like this before but here it goes. I’ve was diagnosed with PCOS back in 2011, been through the ringer with the typical : acne, hair growth (in the wrong places), hair loss (also in the
*trigger alert - this post contains discussion of miscarriage - just a heads up* Hi everyone. I’ve never done anything like this before but here it goes. I’ve was diagnosed with PCOS back in 2011, been through the ringer with the typical : acne, hair growth (in the wrong places), hair loss (also in the
Cystsister87
in
PCOS UK (Verity)
3 years ago
Started on Dapagliflozin last week
Trying to stick with it until I get kidney function checked in the next week or so, but I am feeling awful. I can't do anything, have no energy, slept for about 20 hours yesterday and had horrible migraines with visual disturbance the 4 hours I was awake. No energy to walk anywhere and no eyesight to
Trying to stick with it until I get kidney function checked in the next week or so, but I am feeling awful. I can't do anything, have no energy, slept for about 20 hours yesterday and had horrible migraines with visual disturbance the 4 hours I was awake. No energy to walk anywhere and no eyesight to
laura_dropstitch
Heart Star
in
British Heart Foundation
3 years ago
Metformin and BC
Hello, ive never had pain in the nipple prior to having my period. Its been 3-4 days that I have been feeling pain in my nipples. Have to sleep with my stomach up. The pain feels like its stretching, and the nipples get really hard and very pinful.. any tips? Does this usually happen while taking metformin
Hello, ive never had pain in the nipple prior to having my period. Its been 3-4 days that I have been feeling pain in my nipples. Have to sleep with my stomach up. The pain feels like its stretching, and the nipples get really hard and very pinful.. any tips? Does this usually happen while taking metformin
Kakakalo
in
Fertility Network UK
3 years ago
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