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Experiences with
Androgen deprivation therapy (ADT)
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Is there seasonality to testosterone levels?
My
ADT
treatments (Lupron/Abiraterone/Prednisone) ended on May 02 2023 at which point both my PSA and Testosterone were flat lined. Here are the results of the four times I have been tested since the end of the
ADT
.
My
ADT
treatments (Lupron/Abiraterone/Prednisone) ended on May 02 2023 at which point both my PSA and Testosterone were flat lined. Here are the results of the four times I have been tested since the end of the
ADT
.
Mascouche
in
Advanced Prostate Cancer
3 months ago
Firmagon seems to have stopped suppressing testosterone
Hi everyone I have been taking firmagon
adt
treatment for 6 years for stage 4 cancer last 2 blood tests have one a month showed increase in testosterone 0.76 in December then January test 1.76 this last test also showed a rise in psa has anyone had this problem I'm getting the shot regularly
Hi everyone I have been taking firmagon
adt
treatment for 6 years for stage 4 cancer last 2 blood tests have one a month showed increase in testosterone 0.76 in December then January test 1.76 this last test also showed a rise in psa has anyone had this problem I'm getting the shot regularly
johnscats
in
Advanced Prostate Cancer
4 months ago
Brain Fog or Dimentia?
Is it possible to blame
ADT
and Zytiga? My husband has been on Ellegaard for five years and Zytiga for 2 1/2. Years, he seems to have a lot of memory issues lately, and I fear it’s only getting worse Any thoughts or experiences on this? Would a vacation from all this help?
Is it possible to blame
ADT
and Zytiga? My husband has been on Ellegaard for five years and Zytiga for 2 1/2. Years, he seems to have a lot of memory issues lately, and I fear it’s only getting worse Any thoughts or experiences on this? Would a vacation from all this help?
Keeper70
in
Advanced Prostate Cancer
2 months ago
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Update recent PSMA
So expect to add to
ADT
, abi or enza or darolutamide in a short while, with PSA going up on a fast double. Trying to find out if Nubeqa is worth it regarding technical difference in progression and overall survival, compared to abiraterone. Abi may be better in some ways. thanks.
So expect to add to
ADT
, abi or enza or darolutamide in a short while, with PSA going up on a fast double. Trying to find out if Nubeqa is worth it regarding technical difference in progression and overall survival, compared to abiraterone. Abi may be better in some ways. thanks.
kainasar
in
Advanced Prostate Cancer
26 days ago
considering stopping adt/abiraterone to see what happens
it’s been 8 months since I found myself to have a PSA of 70, it is now 0.0 and I am due for the
ADT
injection. I have coupled standard treatment with rife, mushrooms, ivermectin, fenbendazole, apricot seeds, green tea, vit e, graviola.
it’s been 8 months since I found myself to have a PSA of 70, it is now 0.0 and I am due for the
ADT
injection. I have coupled standard treatment with rife, mushrooms, ivermectin, fenbendazole, apricot seeds, green tea, vit e, graviola.
Nowhereman9
in
Advanced Prostate Cancer
3 months ago
PCA Cure and when?
PSA is 0 on
ADT
and Abiraterone and methylprednisolone. Averaged 8,600 steps/day. I have just started to add occasional sprinting. I am taking multiple supplements. I am greatful that my PSA is 0. I work everyday and pray for a cure. What is our best hope for a cure and when?
PSA is 0 on
ADT
and Abiraterone and methylprednisolone. Averaged 8,600 steps/day. I have just started to add occasional sprinting. I am taking multiple supplements. I am greatful that my PSA is 0. I work everyday and pray for a cure. What is our best hope for a cure and when?
Nowhereman9
in
Advanced Prostate Cancer
4 months ago
Long term results of high dose radiation and long term ADT
https://www.targetedonc.com/view/high-dose-radiation-plus-long-term-
adt
-improves-survival-in-high-risk-prostate-cancer?
https://www.targetedonc.com/view/high-dose-radiation-plus-long-term-
adt
-improves-survival-in-high-risk-prostate-cancer?
Don_1213
in
Advanced Prostate Cancer
4 months ago
Almost 3 years on ADT + Erleada
I am almost 3 years on
ADT
I was diagnosed as stage 4 with a bone biopsy on a lesion.My MO started me with monthly firmagon injections and zytiga in 2021 july then switched to lupron and Erleada after a few months since I had a reaction to Abi after a couple of months .Erleada also gave me rash in
I am almost 3 years on
ADT
I was diagnosed as stage 4 with a bone biopsy on a lesion.My MO started me with monthly firmagon injections and zytiga in 2021 july then switched to lupron and Erleada after a few months since I had a reaction to Abi after a couple of months .Erleada also gave me rash in
mynacho
in
Advanced Prostate Cancer
20 days ago
ADT and bone loss lost opportunity !?
there is /was so much to think about when I got the Gleason 9 diagnosis after 18 months of being told don’t worry it not high risk and so had failed HIFU. Stupid of me ! I got, with great difficulty a DEXA scan one month after starting LHRH agonist goserelin. No one told me I needed it, and given
there is /was so much to think about when I got the Gleason 9 diagnosis after 18 months of being told don’t worry it not high risk and so had failed HIFU. Stupid of me ! I got, with great difficulty a DEXA scan one month after starting LHRH agonist goserelin. No one told me I needed it, and given
SimMartin
in
Advanced Prostate Cancer
21 days ago
Unexpected early end to ADT
As I wrestled with this decision, the thought of getting back to who I was before the
ADT
started seemed pretty damn good! And I am motivated and excited to rebuild my body and mind. Thoughts?
As I wrestled with this decision, the thought of getting back to who I was before the
ADT
started seemed pretty damn good! And I am motivated and excited to rebuild my body and mind. Thoughts?
Prostateless2020
in
Prostate Cancer Network
3 months ago
Starting clinical trial of AVR-766
I've failed
ADT
, chemo. Keytruda & Pluvicto. Hoping #5 will be the one. Here's more info: https://ir.arvinas.com/news-releases/news-release-details/arvinas-announces-interim-data-arv-766-phase-12-dose-escalation
I've failed
ADT
, chemo. Keytruda & Pluvicto. Hoping #5 will be the one. Here's more info: https://ir.arvinas.com/news-releases/news-release-details/arvinas-announces-interim-data-arv-766-phase-12-dose-escalation
rsgdmd
in
Advanced Prostate Cancer
2 months ago
Starting Chemo in May via trial
Check my bio for background. 2 months into
ADT
therapy after diagnosis in January. I am starting docetaxyl chemo via an NIH trial in May. M9241 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230972/. We are hopeful for both good chemo results as well as a positive response for the immunotherapy.
Check my bio for background. 2 months into
ADT
therapy after diagnosis in January. I am starting docetaxyl chemo via an NIH trial in May. M9241 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10230972/. We are hopeful for both good chemo results as well as a positive response for the immunotherapy.
4tunate1
in
Advanced Prostate Cancer
24 days ago
ADT for almost 2 years
Well, I have gone through surgery, radiotherapy,
ADT
, since my diagnosis in February 2018. It will be 2 years in February next since I started
ADT
and PSA has always been <0.01, but a couple of day ago it came at 0.03.
Well, I have gone through surgery, radiotherapy,
ADT
, since my diagnosis in February 2018. It will be 2 years in February next since I started
ADT
and PSA has always been <0.01, but a couple of day ago it came at 0.03.
Paulo1968
in
Advanced Prostate Cancer
7 months ago
Stage 4. IMRT + HDR Brachytherapy
Currently on
ADT
. I have chosen IMRT followed by HDR Brachytherapy. I'm starting IMRT in January 2024. What was you experience with this combination? Did it work? Any side effects? Thank you for your responses.
Currently on
ADT
. I have chosen IMRT followed by HDR Brachytherapy. I'm starting IMRT in January 2024. What was you experience with this combination? Did it work? Any side effects? Thank you for your responses.
FightCancer101
in
Advanced Prostate Cancer
5 months ago
At the crossroads (again)
My profile is up to date, but, briefly, have failed chemo,
ADT
(am castrate resistant), failed Keytruda and now Pluvicto. Scans yest. & today show progression along with PSA rise. All my mets are in bone. So, my SOC choices are cabazataxel or radium 223.
My profile is up to date, but, briefly, have failed chemo,
ADT
(am castrate resistant), failed Keytruda and now Pluvicto. Scans yest. & today show progression along with PSA rise. All my mets are in bone. So, my SOC choices are cabazataxel or radium 223.
rsgdmd
in
Advanced Prostate Cancer
3 months ago
EMBARK Study: ADT vs Enzalutamide +/- ADT
It compared high risk BCR PCa treated in 3 groups: Lupron
ADT
alone. Enzalutamide plus
ADT
. And Enzalutamide monotherapy. 5 year follow up for metastasis free survival. Results below. Interesting that Enza monotherapy (No
ADT
) was superior to
ADT
and nearly as good as the combined treatment.
It compared high risk BCR PCa treated in 3 groups: Lupron
ADT
alone. Enzalutamide plus
ADT
. And Enzalutamide monotherapy. 5 year follow up for metastasis free survival. Results below. Interesting that Enza monotherapy (No
ADT
) was superior to
ADT
and nearly as good as the combined treatment.
MateoBeach
in
Advanced Prostate Cancer
7 months ago
Age and timing for Triplet therapy?
I started
ADT
with Ogovyx 4 weeks ago and feel no side effects so far. The urologist has set up the addition of the ARI Erleada in 3 weeks, though I would now prefer Nubeqa because it does not cross the blood-brain barrier.
I started
ADT
with Ogovyx 4 weeks ago and feel no side effects so far. The urologist has set up the addition of the ARI Erleada in 3 weeks, though I would now prefer Nubeqa because it does not cross the blood-brain barrier.
vintage42
in
Advanced Prostate Cancer
4 months ago
LEUPRORELIN ACETATE
Any information on results or side effects for this
ADT
Any information on results or side effects for this
ADT
Stevegr
in
Advanced Prostate Cancer
7 months ago
Estrodiol and PC
My husband has been rediagnosed with NMPC he is on
ADT
which is holding the Testosterone very low but psa shot upto 82. New MO is starting Enzalutimide plus continuing
ADT
. Not looking forward to the side effects, but will perservere until psa drops.
My husband has been rediagnosed with NMPC he is on
ADT
which is holding the Testosterone very low but psa shot upto 82. New MO is starting Enzalutimide plus continuing
ADT
. Not looking forward to the side effects, but will perservere until psa drops.
Knittingque
in
Advanced Prostate Cancer
7 months ago
PROTACs: another technique to help with mCRPC
I always wondered, if these protein degraders can basically destroy AR receptors, hence overcome both castration resistance and making the cells refractory to androgens...wouldn't it be useless to continue with
ADT
? Oh well... https://www.sciencedirect.com/science/article/pii/S0753332222015013
I always wondered, if these protein degraders can basically destroy AR receptors, hence overcome both castration resistance and making the cells refractory to androgens...wouldn't it be useless to continue with
ADT
? Oh well... https://www.sciencedirect.com/science/article/pii/S0753332222015013
Maxone73
in
Advanced Prostate Cancer
5 months ago
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