When you are on ADT and become Non metastatic Castrate resistant and your testosterone levels are below zero, what is the cancer feeding off to cause the PSA to still rise? Hoping for your replies so as to give me some understanding. Thank you.
Non metastasis castrate resistant - Advanced Prostate...
Non metastasis castrate resistant
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Sailameme
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2 Replies
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There are multiple causes of castration resistance: among them are amplification of androgen receptors (ARs), AR feeding off of new ligands (other than androgens), ARs altering, AR translocating to the cell nucleus and self-activating, and the cell manufacturing its own androgens.
Totally. Well spoken.
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