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Androgen deprivation therapy (ADT)
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Silly Questions??
1) Why do some advanced prostate cancer patients get offered "vacations", from
ADT
and others don't? 2) Why do some advanced prostate cancer patients have NO Chemo, and go directly to
ADT
+ Abiraterone+Prednisone, while others begin treatment with chemo and radiation?
1) Why do some advanced prostate cancer patients get offered "vacations", from
ADT
and others don't? 2) Why do some advanced prostate cancer patients have NO Chemo, and go directly to
ADT
+ Abiraterone+Prednisone, while others begin treatment with chemo and radiation?
TommyCarz2
in
Advanced Prostate Cancer
2 months ago
After ADT
PSAs have been zero. 2 weeks ago
ADT
& steroids were stopped. The steroids were not weaned. Now he has adrenal insufficiency. Symptoms were mainly extreme fatigue & weakness. The GP put him on hydrocortisone tabs. He has constant nausea.
PSAs have been zero. 2 weeks ago
ADT
& steroids were stopped. The steroids were not weaned. Now he has adrenal insufficiency. Symptoms were mainly extreme fatigue & weakness. The GP put him on hydrocortisone tabs. He has constant nausea.
Catmama5
in
Advanced Prostate Cancer
12 days ago
On treating micro-metastatic disease
Thereafter just monitor the PSA for any rise, and use PSMA PET scan to locate any cancer and to radiate whatever spots of cancer that are found.This May I will reach the one year mark of my
ADT
and seriously considering stopping the
ADT
because of the side effects... fatigue, muscle loss, forgetfulness
Thereafter just monitor the PSA for any rise, and use PSMA PET scan to locate any cancer and to radiate whatever spots of cancer that are found.This May I will reach the one year mark of my
ADT
and seriously considering stopping the
ADT
because of the side effects... fatigue, muscle loss, forgetfulness
John347
in
Advanced Prostate Cancer
2 months ago
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Using Enzalutamide, Darolutamide, Apalutamide only.
I'm particularly interested if you transitioned to a "mide" only from first level
ADT
only, and are metastatic to bones/organs. Thanks.
I'm particularly interested if you transitioned to a "mide" only from first level
ADT
only, and are metastatic to bones/organs. Thanks.
dhccpa
in
Prostate Cancer Network
1 month ago
New data about ARASENS trial: it seems to work well after longer observation
Post-Hoc Analysis of ARASENS Reinforces Use of Darolutamide/
ADT
/Docetaxel Combo as SOC in mHSPC https://www.onclive.com/view/post-hoc-analysis-of-arasens-reinforces-use-of-darolutamide-
adt
-docetaxel-combo-as-soc-in-mhspc
Post-Hoc Analysis of ARASENS Reinforces Use of Darolutamide/
ADT
/Docetaxel Combo as SOC in mHSPC https://www.onclive.com/view/post-hoc-analysis-of-arasens-reinforces-use-of-darolutamide-
adt
-docetaxel-combo-as-soc-in-mhspc
Maxone73
in
Advanced Prostate Cancer
3 months ago
ADT or Orchiectomy & side effects
I have been on
ADT
for 18 months the Side effects are a little better but still horrible!! Q) If i have a Orchiectomy, can I stop the
ADT
therapy altogether? Currently on Xtandi and Orgovox. thanks
I have been on
ADT
for 18 months the Side effects are a little better but still horrible!! Q) If i have a Orchiectomy, can I stop the
ADT
therapy altogether? Currently on Xtandi and Orgovox. thanks
lookout4
in
Advanced Prostate Cancer
3 months ago
Proton Treatment - When to start the ADT relative to simulation and CT of the prostate
Another doctor tells me I should start the
ADT
at the same time as I do the space OAR and simulation and cat scan, which will precede the start of the radiation by maybe 2 weeks. My concern about the second doctor's protocol is that the
ADT
will shrink the prostate and the tumors.
Another doctor tells me I should start the
ADT
at the same time as I do the space OAR and simulation and cat scan, which will precede the start of the radiation by maybe 2 weeks. My concern about the second doctor's protocol is that the
ADT
will shrink the prostate and the tumors.
CBRD
in
Advanced Prostate Cancer
2 months ago
ADT & Mets
Are we wasting time going onto
ADT
if that treatment is mainly for contained PCa? Or will the
ADT
put a lid on the Mets wherever they are in our body? Keep in mind that we are totally oblivious of having Mets at the time of starting
ADT
.
Are we wasting time going onto
ADT
if that treatment is mainly for contained PCa? Or will the
ADT
put a lid on the Mets wherever they are in our body? Keep in mind that we are totally oblivious of having Mets at the time of starting
ADT
.
CJ1958
in
Advanced Prostate Cancer
3 months ago
One questions doctors never seem to be able to answer is at what PSA level do you start to experience pain or physical problems?
If you have had surgery, Salvage Radiation,
ADT
, SRBT and then stopped
ADT
with a continuing rise in you PSA when did you start to have pain or physical problems?
If you have had surgery, Salvage Radiation,
ADT
, SRBT and then stopped
ADT
with a continuing rise in you PSA when did you start to have pain or physical problems?
Exrunner
in
Advanced Prostate Cancer
2 months ago
ARASENS TRIAL: Darolutamide
This Kaplan-Mieir plot show the Castration - Resistant Prostate Cancer Free survival probability (%) vs time for two groups: (A) Darolutamide +
ADT
+ Docetaxel, versus (B) Placebo +
ADT
+ Docetaxel.
This Kaplan-Mieir plot show the Castration - Resistant Prostate Cancer Free survival probability (%) vs time for two groups: (A) Darolutamide +
ADT
+ Docetaxel, versus (B) Placebo +
ADT
+ Docetaxel.
janebob99
in
Advanced Prostate Cancer
2 months ago
Testosterone Recovery After ADT - Updated Plot
ADT
duration of 3-9 months fall roughly on the same curve, and
ADT
of 18-24 roughly fall on the same line. Bob
ADT
duration of 3-9 months fall roughly on the same curve, and
ADT
of 18-24 roughly fall on the same line. Bob
janebob99
in
Prostate Cancer Network
2 months ago
Low Testosterone reduces Survival by a huge amount.
The cohort is 58 men with unfavorable intermediate risk who underwent RT and 6-months of
ADT
. The important takeaway is that having a low testosterone (T < 280 ng/dL) after completing
ADT
is associated with
extremely poor
survival outcomes.
The cohort is 58 men with unfavorable intermediate risk who underwent RT and 6-months of
ADT
. The important takeaway is that having a low testosterone (T < 280 ng/dL) after completing
ADT
is associated with
extremely poor
survival outcomes.
janebob99
in
Prostate Cancer Network
2 months ago
Sciatica
I went off
ADT
9 months ago after 6 months of Elegard depot treatment following prostate radiation. I know that many of the side effects of
ADT
can persist months and even years after stopping Elegard (Lupron).
I went off
ADT
9 months ago after 6 months of Elegard depot treatment following prostate radiation. I know that many of the side effects of
ADT
can persist months and even years after stopping Elegard (Lupron).
sciaticaman
in
Advanced Prostate Cancer
4 months ago
Can we trust AI analysis?
The first chose no
ADT
with radiation and the second chose 12 months of
ADT
after surgery and follow up radiation after PSA rise. I guess only time and luck will tell if that was the correct decision for each of us.
The first chose no
ADT
with radiation and the second chose 12 months of
ADT
after surgery and follow up radiation after PSA rise. I guess only time and luck will tell if that was the correct decision for each of us.
Mgtd
in
Prostate Cancer Network
3 months ago
Why do MO's continue to prescribe Lupron ADT for Castrate-Resistant men?
I've never understood why MO's continue to prescribe Lupron
ADT
(or equivalent ) for men who are
castrate-resistant (CRPC
). Isn't that the definition of CRPC, namely, that
ADT
is no longer working for those men?
I've never understood why MO's continue to prescribe Lupron
ADT
(or equivalent ) for men who are
castrate-resistant (CRPC
). Isn't that the definition of CRPC, namely, that
ADT
is no longer working for those men?
janebob99
in
Advanced Prostate Cancer
16 days ago
Effect of Baseline T on T-Recovery Time
Increasing the duration of
ADT
increases the T-recovery time, in general.
Increasing the duration of
ADT
increases the T-recovery time, in general.
janebob99
in
Prostate Cancer Network
2 months ago
ADT and crying
Wondering if there is a solution other than stopping
ADT
all together ? I have about had it with the feminizing effects of
ADT
drugs….
Wondering if there is a solution other than stopping
ADT
all together ? I have about had it with the feminizing effects of
ADT
drugs….
joeguy
in
Advanced Prostate Cancer
4 months ago
RT with ADT Relogolix (Orgovyx) vs Enzalutamide (Xtandi) Side Effect Differences?
Conclusion "...enzalutamide may be as efficacious as
ADT
as an adjuvant treatment in combination with RT. It may be better tolerated than
ADT
as well."
Conclusion "...enzalutamide may be as efficacious as
ADT
as an adjuvant treatment in combination with RT. It may be better tolerated than
ADT
as well."
jazj
in
Advanced Prostate Cancer
2 months ago
Erleada/ADT
hey so when are the side effects are supposed to kick in… started
ADT
in Mid October and Erleada mid January. Thanks in advance.
hey so when are the side effects are supposed to kick in… started
ADT
in Mid October and Erleada mid January. Thanks in advance.
Leaffan57
in
Advanced Prostate Cancer
3 months ago
ADT Holiday?
I'm posting for my husband. Gleason 9, cdk12, reoccurrence 18 months after RP. Scans cancer in lymph node and possibly sternum. Had radiation and 2 successful years of Orgovyx and Zytiga. Dr says he can take a holiday from meds but my husband is concerned that the cancer will return without meds
I'm posting for my husband. Gleason 9, cdk12, reoccurrence 18 months after RP. Scans cancer in lymph node and possibly sternum. Had radiation and 2 successful years of Orgovyx and Zytiga. Dr says he can take a holiday from meds but my husband is concerned that the cancer will return without meds
RunnerBiker
in
Advanced Prostate Cancer
3 months ago
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