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Osteoporosis
Hello Everybody, I had a DEXA scan in 2020, as far as I can see the only worrying result was the neck of femur -2.7. I have just had another DEXA scan on a different machine, and the same result was -2.9. To me, that is not a great difference, having been on steroids for 2 1/2 years. I now have been
Hello Everybody, I had a DEXA scan in 2020, as far as I can see the only worrying result was the neck of femur -2.7. I have just had another DEXA scan on a different machine, and the same result was -2.9. To me, that is not a great difference, having been on steroids for 2 1/2 years. I now have been
Hollyberry12
in
PMRGCAuk
2 years ago
Selective amino acid restriction therapy (SAART)
This is a follow-on from something that came up in the "
Cysteine depletion sensitizes prostate cancer cells to agents that enhance DNA damage and to immune checkpoint inhibition"
post. Some here may be unfamiliar with the idea of selective amino acid restriction. I have never been tempted to
This is a follow-on from something that came up in the "
Cysteine depletion sensitizes prostate cancer cells to agents that enhance DNA damage and to immune checkpoint inhibition"
post. Some here may be unfamiliar with the idea of selective amino acid restriction. I have never been tempted to
pca2004
in
Fight Prostate Cancer
1 year ago
Blood test results Vitamins / Digestive problems
Blood results done by GP : “ Serum folate 4 ug/L Serum ferritin 21 ug/L low iron stores Serum vitamin B12 513 ng/L. ” Vit D not done. I see Tesco are offering cheap tests for various vits. Thoughts ? I am housebound so I take vit D. 25 ug daily. Also omega 3 fish oil and a multivitamin. I was
Blood results done by GP : “ Serum folate 4 ug/L Serum ferritin 21 ug/L low iron stores Serum vitamin B12 513 ng/L. ” Vit D not done. I see Tesco are offering cheap tests for various vits. Thoughts ? I am housebound so I take vit D. 25 ug daily. Also omega 3 fish oil and a multivitamin. I was
Applethorpe
in
Thyroid UK
1 year ago
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Cysteine depletion sensitizes prostate cancer cells to agents that enhance DNA damage and to immune checkpoint inhibition
New paper below [1]. I have always been interested in ways in which a treatment might be enhanced by supplements or dietary changes. (or repurposed drugs) In this case, "depletion of L-cysteine/cystine" was via "an engineered human enzyme, Cyst(e)inase". "PCa cells treated with Cyst(e)inase lead
New paper below [1]. I have always been interested in ways in which a treatment might be enhanced by supplements or dietary changes. (or repurposed drugs) In this case, "depletion of L-cysteine/cystine" was via "an engineered human enzyme, Cyst(e)inase". "PCa cells treated with Cyst(e)inase lead
pca2004
in
Fight Prostate Cancer
1 year ago
zoledronic acid infusion long term side effects
I am due to have zoledronic infusion, I have been reading the long term side effects ,it's enough to put anyone off,has anyone who has had infusions long term suffered with side effects, I have severe osteoporosis-2.5 but at the moment I am only getting occasional back ache and a bit breathless on
I am due to have zoledronic infusion, I have been reading the long term side effects ,it's enough to put anyone off,has anyone who has had infusions long term suffered with side effects, I have severe osteoporosis-2.5 but at the moment I am only getting occasional back ache and a bit breathless on
Radars
in
Bone Health and Osteoporosis UK
2 years ago
How much is too much D3
Any views on taking 10,000 iu d3 daily? There’s evidence that it’s ‘safe and well tolerated’ I went to see my bone consultant today, he wasn’t impressed by me taking this amount but my calcium level is good and my dexa results have gone from -2.6 to -2.1 in 2 years I also take k2 and magnesium ,
Any views on taking 10,000 iu d3 daily? There’s evidence that it’s ‘safe and well tolerated’ I went to see my bone consultant today, he wasn’t impressed by me taking this amount but my calcium level is good and my dexa results have gone from -2.6 to -2.1 in 2 years I also take k2 and magnesium ,
Deee64
in
Bone Health and Osteoporosis UK
2 years ago
ANRC Plus instead of B complex?
The below is my own work which I am simply sharing. I have no other agentia other than to invite comments and zero expectations. I make no claim to legitimacy or accuracy. I have less than zero medical training. It makes sense to me that any supplement should be checked to insure that an ingredient
The below is my own work which I am simply sharing. I have no other agentia other than to invite comments and zero expectations. I make no claim to legitimacy or accuracy. I have less than zero medical training. It makes sense to me that any supplement should be checked to insure that an ingredient
WIZARD6787
in
Pernicious Anaemia Society
2 years ago
ART Vit D and Prostate Cancer (PCa) by Dr Campbell UK Podcast
Dr Campbell, UK, has made a summary of recent investigations and studies on VIT D and its effect on PCa specifically and cancer generally. Of import is his discussiono on the finding on PCa and African Americans; they have a genomic risk factor that leads to more aggressive PCa, BUT respond quickly
Dr Campbell, UK, has made a summary of recent investigations and studies on VIT D and its effect on PCa specifically and cancer generally. Of import is his discussiono on the finding on PCa and African Americans; they have a genomic risk factor that leads to more aggressive PCa, BUT respond quickly
RMontana
in
Active Surveillance - Prostate Cancer
1 year ago
Alendronic acid and depression
I came off Alendronic Acid because I didn’t think it was agreeable with me, it was a couple of months ago and I can’t remember the exact reason but it was on the suggestion of a consultant I was seeing for another reason and I have been fine. I started to take it again 3 weeks ago because I knew I
I came off Alendronic Acid because I didn’t think it was agreeable with me, it was a couple of months ago and I can’t remember the exact reason but it was on the suggestion of a consultant I was seeing for another reason and I have been fine. I started to take it again 3 weeks ago because I knew I
Diver6
in
Bone Health and Osteoporosis UK
2 years ago
How to recover from a failed flare taper
PMR diagnosed: June 2021 Intial prednisone taper 30 to 8 mg/dy by Aug 2022—then flare 14 months: Successful flare recovery to 7.5 mg/dy by end of 2022-then flare 3 months: Inadequate flare recovery to about11 mg/dy through this March. I did not get above the pain threshold and was tolerating more
PMR diagnosed: June 2021 Intial prednisone taper 30 to 8 mg/dy by Aug 2022—then flare 14 months: Successful flare recovery to 7.5 mg/dy by end of 2022-then flare 3 months: Inadequate flare recovery to about11 mg/dy through this March. I did not get above the pain threshold and was tolerating more
JASpmr
in
PMRGCAuk
1 year ago
When does supplementation become toxic or counter-productive?
My Dear Fellow Adventurers, Firstly, thank you for the wealth of information and inspiration - having this commuity makes so much difference! I have a question today, that I have already asked both my doctor and pharmacist (neither were able to help): as I add a new supplement every few months
My Dear Fellow Adventurers, Firstly, thank you for the wealth of information and inspiration - having this commuity makes so much difference! I have a question today, that I have already asked both my doctor and pharmacist (neither were able to help): as I add a new supplement every few months
Jdig
in
Cure Parkinson's
2 years ago
teeth whitening
good morning everyone I don’t know if anyone on here has had any experience with tooth whitening products, only I’ve seen an advert for a tooth whitening powder which I’m very tempted to try, especially as it’s dentist approved and is peroxide-free. I’m just wondering about the Alendronic Acid I’m
good morning everyone I don’t know if anyone on here has had any experience with tooth whitening products, only I’ve seen an advert for a tooth whitening powder which I’m very tempted to try, especially as it’s dentist approved and is peroxide-free. I’m just wondering about the Alendronic Acid I’m
Doraflora
in
PMRGCAuk
2 years ago
Creaky Joints!
Hello Everyone. Having had trouble going down to 4mg Pred previously, I'm nearing the end of a 6 month taper from 5mg to 4mg. Over the last couple of months I have had a really stiff neck and shoulder pain on one side. I can't decide if this is symptoms coming back, or osteoarthritis, because I definitely
Hello Everyone. Having had trouble going down to 4mg Pred previously, I'm nearing the end of a 6 month taper from 5mg to 4mg. Over the last couple of months I have had a really stiff neck and shoulder pain on one side. I can't decide if this is symptoms coming back, or osteoarthritis, because I definitely
AshPen9
in
PMRGCAuk
1 year ago
alendronic problems
just trying to check my stomach ache, dizziness at times, reflux and chest pain are all from alendronic acid, as I take statins as well. Feel bloated and lack of appetite. What alternatives are there to increase bone strength? Anyone have these symptoms ?
just trying to check my stomach ache, dizziness at times, reflux and chest pain are all from alendronic acid, as I take statins as well. Feel bloated and lack of appetite. What alternatives are there to increase bone strength? Anyone have these symptoms ?
Doggiegirl
in
PMRGCAuk
2 years ago
Taking Alendronic Acid & Dentists won't touch me!
Wanted to have some dental work done & on speaking to a specialist dental surgery, when they heard I was taking Alendronic Acid & Prednisolone they just didn't want to touch me. Have been to visit my regular dentist today who said anything like an extraction or implant he wouldn't do & I would have
Wanted to have some dental work done & on speaking to a specialist dental surgery, when they heard I was taking Alendronic Acid & Prednisolone they just didn't want to touch me. Have been to visit my regular dentist today who said anything like an extraction or implant he wouldn't do & I would have
Purpleprimate
in
PMRGCAuk
2 years ago
amino acids not recognised as essential in humans such as taurine play a role in fibromyalgia,
In this study, researchers measured the level of 20 amino acids (critical components of proteins). They found that overall levels of amino acids were lower in fibromyalgia and that seven amino acids were especially low, including taurine, alanine, tyrosine, valine, methionine, phenylalanine, and threonine.The
In this study, researchers measured the level of 20 amino acids (critical components of proteins). They found that overall levels of amino acids were lower in fibromyalgia and that seven amino acids were especially low, including taurine, alanine, tyrosine, valine, methionine, phenylalanine, and threonine.The
LawrenceT
in
Fibromyalgia Action UK
1 year ago
9 years and counting with PMR!
Feeling frustrated having been 'diagnosed' with PMR in 2014, initially controlled with prednisolone and then Methotrexate introduced in 2018 after I queried my diagnosis and treatment plan. Initially I was able to reduce preds down to 5 mg daily with 25mgs methotrexate weekly but I am ow struggling again
Feeling frustrated having been 'diagnosed' with PMR in 2014, initially controlled with prednisolone and then Methotrexate introduced in 2018 after I queried my diagnosis and treatment plan. Initially I was able to reduce preds down to 5 mg daily with 25mgs methotrexate weekly but I am ow struggling again
MC60
in
PMRGCAuk
2 years ago
Will Alendronic Acid affect my RLS?
I have Osteopenia and have been advised to start taking Alendronic Acid to prevent me developing Osteoporosis but am worried it might make my RLS worse. I take Requip and seem to have it under control.
I have Osteopenia and have been advised to start taking Alendronic Acid to prevent me developing Osteoporosis but am worried it might make my RLS worse. I take Requip and seem to have it under control.
Brenda48
in
Restless Legs Syndrome
2 years ago
ursodeoxycholic acid
hi everyone, Hope your all well. I’ve had pbc for about a year now. I take 500mg of ursodeoxycholic acid twice per day. I suffer from waves of nausea at different times throughout the day. Today I spoke to Gastroenterologist on the phone and he told me to take the medication 1000mg at bedtime. Does
hi everyone, Hope your all well. I’ve had pbc for about a year now. I take 500mg of ursodeoxycholic acid twice per day. I suffer from waves of nausea at different times throughout the day. Today I spoke to Gastroenterologist on the phone and he told me to take the medication 1000mg at bedtime. Does
Sunliver
in
PBC Foundation
2 years ago
Hello & Should I do private tests?
Hi! First post here after reading through the forum for a week or so. I'd like to start by saying a big THANK YOU to all the knowledgeable folks who have posted on here, especially the Administrators who are incredibly helpful. I've very recently been diagnosed with autoimmune thyroid disease and have
Hi! First post here after reading through the forum for a week or so. I'd like to start by saying a big THANK YOU to all the knowledgeable folks who have posted on here, especially the Administrators who are incredibly helpful. I've very recently been diagnosed with autoimmune thyroid disease and have
ERIC107
in
Thyroid UK
1 year ago
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