Off pristiq: I took my last dose of... - Anxiety and Depre...

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Off pristiq

Twistedopher profile image
7 Replies

I took my last dose of pristiq on Tuesday. I have been a guinea pig for snri's since September. My psychiatrist wants me to washout until Tuesday and then start me on an ssri. I suggested Prozac because it worked wonderfully in the past. I have been so depressed for so long I am having a real hard time seeing a light at the end of the tunnel. It just never goes away. The depression turns to anxiety. Then panic. Then I cry uncontrollably. I want so hard to believe that it will get better. I am a Christian. Husband to a wonderful woman for 22 years. Father of a 14 y.o. son, a 14 y.o. adopted niece, an 11 y.o. daughter, and a happily married and on her own daughter of 25 y.o. I have so, so, so much to be thankful for. Yes I can't find the way out of this depression. Is it because I jave been on the medication train for so long and I need to detox? Is it because I'm broken and will never be the father I used to be? Do I simply need to try an ssri instead of those stupid snri's that have all made my condition worse it seems. I feel so lost in this struggle. I am an open book and would love to get feedback from someone.

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Twistedopher
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7 Replies
Dolphin14 profile image
Dolphin14

For some people it can take quite awhile to get the right medication regime.

Don't lose hope.

🐬

Ryanlion profile image
Ryanlion

Dont give in to despair or lose hope. You are not broken either. I know where your coming from , ive been there. Have you tried talking therapy to get to the bottom of your depression? One of the anti depressant types are the tricyclics. Very old but in my opinion better than the more up to date ones. I took Clomipramine for 15 years before it stopped working for me. It was brilliant, tough side effects but they eventually passed. I wish you well on finding the correct anti depressant and i agree about the modern antidepressants, for some they are great but for others they are worse than useless.

yhsbirny profile image
yhsbirny

If Prozac worked well for you in the past , it should work again, as should another ssri. If you want to try something completely different, ask your doctor about Parn.ate or Nardil. They are a different class of anti-depressants, MAO inhibitors. They work mainly on dopamine. They come witha few minor dietary restrictions, but will often work when nothing else does, even ECT. They are very old drugs (at least 50 years old) that are just starting to be more widely used again.

designguy profile image
designguy

You might see about doing a psychopharmacological test that uses your dna to determine which meds a better suited for you genetically. It can help take a lot of the guesswork out of the process. My test was from Genesight and paid for by my insurance. I had tried a half dozen different meds without success and tried one my test recommended and it has worked well. It also showed that none of previous meds I had tried were right for me.

Twistedopher profile image
Twistedopher

I did take the genesight swab, the only thing it seems to have gotten right is the mthfr double mutation.

Good for you! Pristiq is the most God Awful Rat Poison I have ever experienced. I only took it for 3 weeks. then I filled my last script for Effexor XR. THEN, I changed quacks and went on Celexa.

Happygolf profile image
Happygolf in reply to

I was on it for 3 months,just got off it for few days muscle tremors and the weakness in my hands,just wondering if you experience any of these symptoms

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