Posts - Advanced Prostate Cancer | HealthUnlocked

Advanced Prostate Cancer

22,277 members•27,978 posts

All posts for September 2017

ADT and resistance proportionality

My Dr said, based on experience with his large patient population over decades, that formation of resistance is somewhat poroportional to ADT dosage. One of...

My Dr said, based on experience with his large patient population over decades, ...

podsart

•7 years ago

38 Replies

Zytiga-Radiation- Nausea

We're new here - hubby too sick to post - no interest in anything due to degree of nausea & pain. Husband is miserable since Zytiga - more pain and extreme...

We're new here - hubby too sick to post - no interest in anything due to degree...

MerryMack

•7 years ago

28 Replies

Looking for oncology recommendations in Los Angeles and surrounding cities.

Hi, currently my father has a medical oncologist at Keck USC. We are happy with her but I am looking for Simone that specializes in prostate cancer treatments....

Hi, currently my father has a medical oncologist at Keck USC. We are happy with ...

Daddysdaughter

•7 years ago

15 Replies

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Gut Microbiome & Prostate Cancer.

New study below. Popular interest in the gut microbiome is probably due to Dr. David Perlmutter, a neurologist & author of "Brain Maker: The Power of Gut...

New study below. Popular interest in the gut microbiome is probably due to Dr. D...

pjoshea13

•7 years ago

6 Replies

AR-V7 testing should be done before Xtandi?

My father will begin using Xtandi. Should he have this test done prior to starting?

My father will begin using Xtandi. Should he have this test done prior to starti...

Daddysdaughter

•7 years ago

12 Replies

Sclerotic change

My husband is having increasing rib pain despite a falling PSA. In most recent Ct scan his lymphnodes have shown reduction indicating treatment response. I...

My husband is having increasing rib pain despite a falling PSA. In most recent C...

Blair77

•7 years ago

3 Replies

hang on as long as you can. help is on the way.

https://www.nature.com/articles/ncomms15528

wifeofvet

•7 years ago

15 Replies

clarity

when i made the comment re/ the internet and snake oil , i was talking about the internet in general not Health Unlocked. i got some feed back that might...

when i made the comment re/ the internet and snake oil , i was talking about the...

joeoconnell

•7 years ago

5 Replies

Lynparza (olaparib), a PARP inhibitor, before CRPC.

Some hype over a new study [1]: "Our data suggest that ADT can functionally impair HR {defects} prior to the development of castration resistance and that,...

Some hype over a new study [1]: "Our data suggest that ADT can functionally imp...

pjoshea13

•7 years ago

4 Replies

STAMPEDE Trial: Adding Abiraterone Acetate or Docetaxel Plus Prednisone to ADT.

Data "presented during ESMO 2017, the Annual Congress of the European Society for Medical Oncology in Madrid, Spain"....

Data "presented during ESMO 2017, the Annual Congress of the European Society fo...

pjoshea13

•7 years ago

5 Replies

New Yorker Cancer Article is a must read

I just finished a good article regarding Cancer in the 9/11 issue of the "New Yorker" entitled "The Invasion Equation". It documents the relationship between...

I just finished a good article regarding Cancer in the 9/11 issue of the "New Yo...

timfiskwa

•7 years ago

6 Replies

Testosterone Reduction of ≥ 480 ng/dL Predicts Favorable Prognosis of Japanese Men With Advanced PCa on ADT.

New study - another oddity. "With regard to overall survival, ... nadir testosterone ≤ 20 ng/dL (hazard ratio = 0.44 ...) and testosterone reduction ≥ 480...

New study - another oddity. "With regard to overall survival, ... nadir testost...

pjoshea13

•7 years ago

Be the first to reply

Rapidly decreasing level of PSA during ADT is a risk factor for early progression to CRPC.

New study - odd finding? "... a velocity of PSA decline >11 ng/mL per month (HR 2.124 ...), and a time to PSA nadir ≤9 months (HR 0.276 ...) were significantly...

New study - odd finding? "... a velocity of PSA decline >11 ng/mL per month (HR ...

pjoshea13

•7 years ago

21 Replies

Missing Zytiga

UPS didn't deliver my meds as promised thursday and closed Friday for the duration of the storm. I will miss at least four days of Zytiga. Can anyone tell me...

UPS didn't deliver my meds as promised thursday and closed Friday for the durati...

George79

•7 years ago

12 Replies

Jawbone Death

Follow up. Yes had infected tooth removed after 6 months if hospital planning. Saw specialists yesterday who were pleased with the healing. Not as pleased as...

Follow up. Yes had infected tooth removed after 6 months if hospital planning. ...

Scruffybut1

•7 years ago

5 Replies

Upfront Docetaxel or upfront Zytiga

Upfront Zytiga seems to be way less toxic and offer an even better benefit. My hubby just finished upfront Docetaxel and is wiped out. I wish this data would...

Upfront Zytiga seems to be way less toxic and offer an even better benefit. My h...

Blair77

•7 years ago

13 Replies

Feeling like I'm behind on the treatment choices.

Can anyone explain gene mutations and PCA? Or is there a link I can read about it..

Can anyone explain gene mutations and PCA? Or is there a link I can read about i...

Daddysdaughter

•7 years ago

4 Replies

Testosterone inhibits the growth of PCa (in mice).

New study below. The BAT concept is that supraphisiological testosterone [T] is required for therapeutic effect. My own use of T has aimed to raise levels to...

New study below. The BAT concept is that supraphisiological testosterone [T] is ...

pjoshea13

•7 years ago

12 Replies

Presurgical weight loss, tumour traits & biomarkers.

Interesting new study below. A 7 week intervention with the aim of 1 kg (2.2 lbs) weight loss /week in "overweight and obese men with prostate cancer." Mean...

Interesting new study below. A 7 week intervention with the aim of 1 kg (2.2 lbs...

pjoshea13

•7 years ago

Be the first to reply

Enzalutamide & drug interactions.

New Dutch paper below [1] In a recent post, I mentioned that Xtandi could cause the liver to metabolize more of certain drugs, thereby weakening the dose: Wiki...

New Dutch paper below [1] In a recent post, I mentioned that Xtandi could cause ...

pjoshea13

•7 years ago

1 Reply

Closer to death

Someone wrote the following to me. "Today, I feel closer to death then ever. " I'm wondering how you (our group) might feel about the idea of being closer to...

Someone wrote the following to me. "Today, I feel closer to death then ever. " ...

Darryl

Partner•7 years ago

23 Replies

Lactate Effects Immune Response in PCa

Gus https://www.ncbi.nlm.nih.gov/pubmed/28862200

gusgold

•7 years ago

1 Reply

Darolutamide and mCRPC...New Promising Drug

Darolutamide can work even when resistance to Xtandi and Zytiga has developed Gus http://www.tandfonline.com/doi/full/10.1080/14656566.2017.1329820

Darolutamide can work even when resistance to Xtandi and Zytiga has developed Gu...

gusgold

•7 years ago

12 Replies

award winning

some times i think the internet should be presented the academy award for the best snake oil presentations

some times i think the internet should be presented the academy award for the be...

joeoconnell

•7 years ago

3 Replies

Ureteral Stent / kidney not draining

Hello gang, it seems my left kidney is not draining properly into my bladder, right one is fine doctor is suggesting we put in a "ureteral stent" right now I...

Hello gang, it seems my left kidney is not draining properly into my bladder, ri...

MrJack

•7 years ago

33 Replies

May be of interest to some

Data as published by canernetwork...

Hidden

•7 years ago

6 Replies

Palmdale, CA presents a proclamation

The Mayor pro tem in Palmdale presented me with the September is prostate cancer awareness month proclamation. I spoke for like 5 minutes and hopefully will...

The Mayor pro tem in Palmdale presented me with the September is prostate cancer...

dockam

•7 years ago

4 Replies

Dr. Surge Jurasunas or Dr. Nalakrats Protocol for mCRPC

It is a tough choice which Docs protocol to follow..so I posted pics of both docs to make the choice easier... Dr. Jurasunas...

It is a tough choice which Docs protocol to follow..so I posted pics of both doc...

gusgold

•7 years ago

4 Replies

Another paper from the controversial PURE study.

New study below. "Reducing saturated fatty acid intake and replacing it with carbohydrate has an adverse effect on blood lipids. Substituting saturated fatty...

New study below. "Reducing saturated fatty acid intake and replacing it with car...

pjoshea13

•7 years ago

5 Replies

New here...

Introducing myself... my husband and I will probably both be posting on here with this profile- but for now mostly will be me. My husband will be 50 in...

Introducing myself... my husband and I will probably both be posting on here wit...

pakb

•7 years ago

17 Replies

Posts - Advanced Prostate Cancer | HealthUnlocked

Advanced Prostate Cancer

All posts for September 2017

ADT and resistance proportionality

Zytiga-Radiation- Nausea

Looking for oncology recommendations in Los Angeles and surrounding cities.

Gut Microbiome & Prostate Cancer.

AR-V7 testing should be done before Xtandi?

Sclerotic change

hang on as long as you can. help is on the way.

clarity

Lynparza (olaparib), a PARP inhibitor, before CRPC.

STAMPEDE Trial: Adding Abiraterone Acetate or Docetaxel Plus Prednisone to ADT.

New Yorker Cancer Article is a must read

Testosterone Reduction of ≥ 480 ng/dL Predicts Favorable Prognosis of Japanese Men With Advanced PCa on ADT.

Rapidly decreasing level of PSA during ADT is a risk factor for early progression to CRPC.

Missing Zytiga

Jawbone Death

Upfront Docetaxel or upfront Zytiga

Feeling like I'm behind on the treatment choices.

Testosterone inhibits the growth of PCa (in mice).

Presurgical weight loss, tumour traits & biomarkers.

Enzalutamide & drug interactions.

Closer to death

Lactate Effects Immune Response in PCa

Darolutamide and mCRPC...New Promising Drug

award winning

Ureteral Stent / kidney not draining

May be of interest to some

Palmdale, CA presents a proclamation

Dr. Surge Jurasunas or Dr. Nalakrats Protocol for mCRPC

Another paper from the controversial PURE study.

New here...

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