I would like to share with you the journey that we have undergone through my Father’s PCa.
My Father is 78, is asymptotic and still works everyday running his business.
Even way back in 2002 my Father’s PSA was 19, but biopsies were always negative as were scans. Although we can assume he has likely had it since then given the PSA reading.
In 2009 it was still at 19 and in 2010 it was at 20.
Throughout this whole time we were doing many complimentary therapies. Too numerous to list here.
My Father got on with his life for a few years but we got a shock when tested in 2014 as his PSA came back at 433.
Dr Bob and Dr Tuckers work made the most sense to us and so we set out to do Intermittent hormone blockade.
Dr Tucker is currently my Father’s oncologist via telemedicine and I also speak to Edward Friedman frequently as well (Will touch more upon his work later)
In March 2014, straight after diagnosis, we flew to a german clinic to do 3 weeks of complimentary therapies, at the same time my Father had started TAB. Using Degarelix, Casodex, Dutesteride and Finisteride.
Scans in Germany revealed no bone metastasis and no PCa in any organs. But several lymph nodes were involved.
After one year of TAB my Father’s PSA was 0.24. Three months after being off hormone therapy (whilst still taking dutesteride and finisteride) his PSA dropped further to 0.21.
During the off period my Father took low dose thalidomide and many other complimentary therapies including cycles of Doxycycline (an antibiotic purposed to kill prostate cancer stem cells) and ProsStay (a combination of Vitamin C and Vitamin K that was demonstrated to slow doubling time)
After a 2.5 year holiday my Father’s PSA hit 206.
Dr Tucker, as well as ourselves did not want to restart hormone blockade till as late as possible, and given my Father was asymptomatic, and we had a very high benchmark with original PSA, we would restart hormone when PSA was 50% of its original value. My Father is also taking Metformin and a statin.
His results from his second round of hormone therapy thus far are as followed.
7th Aug - 206 (Hormone Block Started this date)
7th Sep - 20 (After 1 month on TAB)
6th Oct - 12 (After 2 months on TAB)
3rd Nov - 8.9 (After 3 months on TAB)
30th Nov 2017 - 7.3 (After 4 months on TAB)
In light of this Dr Tucker has had us stop Casodex and we have replaced it with Zytiga.
Obviously we were hoping for a similar drop in PSA as with our first round of hormone blockade but it is falling slower than before.
Going back to Ed Friedman’s work, and through my many years of research as well. I completely concur with him that low testosterone causes PCa, paradoxically can then fuel it when it has taken hold, but can also be used therapeutically.
I am wondering if anybody has any experience on trying high dose testosterone as a way to prevent becoming hormone refractory? I believe Ed called it Bipolar therapy when i last spoke to him about a long while ago.
I was very intrigued by this post by gusgold, which seemed to outline a protocol for it.
I have emailed Ed today so will report back.
As a side point, to who might be interested, I have a friend in LA called Mark Simon, who by all accounts is a genius. He runs the Nutritional Oncology research Institute out there. He utilises a protocol where you restrict methionine (an amino acid all cancer cells rely on) and then intermittently dose high levels of sodium selenite.
I’ve never been able to persuade my Father to become Vegan however, haha, or go on the strict fruit only diet whilst on the protocol.
Additional complimentary therapies we are on and or beginning are;
Cannabis oil (A 1:1 ratio of CBD and THC) - My Father has took a small dose everyday for years but we are upping dosages.
Turkey Tail Mushroom extract
Pao Pereira Extract
FASN inhibitor (luteolin, ellagic acid, ursolic acid, resveratrol and EGCG)
Sorry for the extra long post.
Any other advise or comments would be greatly received as well.