Experiences with

Thalidomide

Is anyone out there taking thalidomide medication and if so to what effect . I will be going onto it soon running out of options apparently.

going to be taking thalidomide tablets in about a weeks time. Anyone else taking them and any good / bad results. I’m in between a rock and a hard place as Dr said. The drug has many different side effects.

Good evening I was wondering if any one has symptoms that I am having the tips of my fingers and toes are extremely sensitive and painful I am on Tarpib and Thalidomide due to having lung cancer and Multiple Myeloma please advise if there is anything I could use to ease the pain Thank you

The TGF-β1 ligand is derived from its direct inhibitor P144, and CRBN is recruited by the widely used ligand thalidomide.

Hi The hematologist has raised the option of prescribing thalidomide. I am taking ruxolitnib 5mg twice daily and inject eprex once weekly zario 3 times a week. I have MF . I will be greatfull for any info form anyone with experience of this drug.

As Ruxolitinib is no longer working well, my haematologist has suggested combining either Danazol, Thalidomide or Prednisone with the Ruxo. Has.anyone any experience of this? What are the pros and cons? I am very worried about the side effects. Thankyou SkipperL

I keep thinking about the Thalidomide drug back in the 60s and how it affected so many babies. The Covid vaccine is so new and I just can’t decide what’s for the best as I know mummy’s can get super ill if they catch Covid. What’s everyone’s thoughts?

But yes, Thalidomide for most of a year for me, starting 10 years ago. Quite rightly only used with great reluctance and care, but can be life saving.

Then I was on Thalidomide. Peripheral neuropathy is a common side effect of Thalidomide and there was a little damage but not that I could feel. I stopped taking Thalidomide then. Today they can see there is more peripheral neuropathy present. Does anyone with Behcets have this problem?

I thought I would just leave this information here in case anyone finds it interesting. My GP gave me a print out of the info. when I saw him last week. I was so impressed that he had not only seen it, but thought about me and printed it out to give me! It may be worth someone following up... https:/

Additional medicines such as Interferon and Thalidomide are suggested to complement the Ruxolitinib. Radiology is an option or in the worst case, having the Spleen removed surgically. I have a telephone consultation on the 19th April and will discuss the options.

I am sure we all remember the thalidomide story! A close cousin of Thalidomide, lenalidomide came onto the Australian market around 2007. It was a gift form God for those who had tried every medical protocol for conditions like Multiple Myeloma, and Amyloidosis and failed.

I am sure we all remember the thalidomide story! Thalidomide, lenalidomide and several newer versions of this drug are now used to treat some blood disorders such as amyloidosys. I am passionate about medical research but somewhere along the way people must come before profits.

My haemo has floated the idea of low dose thalidomide in combination with prednisone as a potential treatment for my advanced myelofibrosis. I have read a couple of articles on the net which suggest quite a good response in reducing anemia and increasing platelets.

"It belongs to the family of drugs called antitumor antibiotics." [5] [6a] Lenalidomide "(trade name Revlimid) is a derivative of thalidomide approved in the United States in 2005.

Drug testing/trials have come a long way since the days of Thalidomide and smoking beagles! These are often presented as facts despite a lack of rigor in the analysis of results – often by internet quacks!

In this case, the drug appears to kill cancer cells directly, and it costs just 70p per day." https://www.theguardian.com/science/2016/jun/12/anti-cancer-drugs-medicine-cabinet-repurposed-aspirin-thalidomide-beta-blockers

Treatments I went through were 2 cycles of HDIL2 and Capcitabine, Thalidomide and INF-A all back in 2002. Has anyone else every experienced this condition?

Odd, perhaps, that Thalidomide & Lenalidomide would show mixed results. & now a cell study from India reports that: "Thalidomide inhibited 'Cell cycle' and 'E2F network', possibly accounting for its synergistic effects with docetaxel.

He has also been taking low dose thalidomide but it has caused some ankle swelling. Any information on latest bits from anybody would be great?