Regular yearly psa test since 2006 because of family history of PC. Psa had always been near 1.0.
01/2013 psa showed slight rise to 3.2.
Inconclusive ultrasound so another psa test in July, psa up now to 9.1
08/26/2013- DRE showed a symmetrical, nontender, nodular right lobe (cT2b), Gleason score of 10 (5+5), involving all 14 cores that were examined, positive for perineural invasion.
-09/23/2013- WBS showed diffuse metastatic disease to the bones, CT scan of the abdomen and pelvis that was negative for visceral or lymph node involvement.
-09/25/2013- ADT started (Lupron)
-02/5/14- started MDV3100-09 (STRIVE): A Multicenter Phase 2, Randomized, Double-Blind, Efficacy and Safety Study of Enzalutamide vs. Bicalutamide in Men with Prostate Cancer who have Failed Androgen Deprivation Therapy.
-07/30/2014- Nov 2014 palliative Docetaxel chemotherapy (c 6)
-Clinical and radiographic progression, MRI spine showed mets, underwent radiation /SRS to C Spine 1800 cGy in 1 fx On Dec 12, 2014 for neck pain.
-April 2015: Started on Xtandi
March 2016: xtandi no longer working had palliative Radiation to pelvic area and middle back for pain.
Discussed second-line chemotherapy with Cabazitaxel vs. Trials vs. AA/P and Radium-223
Favored to proceed with zytiga and Radium-223 after Radiation therapy.
Start Radium-223 today, will hope for some longer term results.
Can't hold job due to symptoms of treatments and foggy head from constant pain meds, but feel blessed to still be here and grateful for time with wife, children and grandchildren.