Experiences with

Docetaxel

This may seem like a blunt or potentially insensitive question, but for those of you who have undergone Docetaxel treatment, how many would say you’re ultimately glad you chose that path? From what I understand, its effectiveness tends to be relatively short-lived.

Docetaxel is a common chemotherapy treatment for prostate cancer, but patients eventually develop resistance to it. The study found that combining docetaxel with mifepristone significantly reduced cancer cell viability.

cancer aggressiveness and docetaxel resistance.

My husband wasn't to try to repeat Docetaxel, I am not sure. Any thoughts? Thank you!

I’m currently between Docetaxel infusion 4 and 5 and have a very painful area underneath the rear of my tongue. I also have a bit of pain in my ear canal. In reading about Docetaxel, I see that mouth sore spots are listed as a side effect.

any study/trial done to show Provenge and Docetaxel can be done concurrently ? Tall_Allenany clinical trial to prove that Docetaxel cat be started along with Provenge. My dad’s PSA is increasing - doubling time is one month (4 weeks).

Dad failed Zytiga, Docetaxel, Pluvicto, Cabazitaxel. He has extensive bone metastases. What’s left? Any other options?

In this Phase II study, participants in Arm A will receive docetaxel if their ctDNA level is 2% or greater, and enzalutamide if their ctDNA level is less than 2%. Participants in Arm B will receive either enzalutamide or docetaxel based on your cancer doctor’s assessment.

I started Docetaxel about 6 weeks ago and have now developed a bad case of the “I’m having a hard time giving a sh-t anymore”. I am 100% safe, and have an appointment with a counselor, but this is so not typical of me. Thanks in advance. Jim

unfortunately my dads PSA is still increasing even after receiving docetaxel + Carboplatin. He completed DCT in December and Chemotherapy started in December 2024. He got 4 infusions of carboplatin and Docetaxel but PSA is rising again. Nothing seeems to be working for my old man.

My hubby has had 5 Docetaxel infusions. His PSA dropped significantly after first 2 infusions and started rising by a point or two before the 4. & 5th infusions. Should we just stop since he seems to have reached the most it is going to do?

https://prostatewarriors.com/2025/01/06/phase-2-adaptive-adt-and-docetaxel-trial-for-mcspc/

Has anyone else experienced a similar reaction with docetaxel and were able to successfully undergo a second attempt with cabazitaxel? I’d greatly appreciate any insights or advice. Thank you!

Given my mission to get upfront Lu-177 in 2021 (3 infusions) followed by 3 Docetaxel I was pleased to listen to this lecture: https://www.urotoday.com/video-lectures/esmo-2024/video/4297-upfrontpsma-trial-lutetium-psma-docetaxel-in-mhspc-arun-azad.html My blood test today came back PSA undetectable

anyone have success on Cabazitaxel when Docetaxel failed

A new population-adjusted analysis confirms that the combination of darolutamide, ADT, and docetaxel significantly improves survival in men with metastatic hormone-sensitive prostate cancer (mHSPC).

Does anyone know if there’s a steroid that they can substitute for Pednisone during Docetaxel chemotherapy?

I read that docetaxel is the second most toxic chemo and can't disagree. My question, though, is " If docetaxel is so powerful, does it's effect way overpower anything else I can do like diet ?" My MO responded that we shouldn't eat processed food. OK, but what about sugar, red meat, even exercise.

Anyone have any experience with long term success after Docetaxel? Thanks for any responses!

The oncologist isn’t sure if it’s the Nubeqa or docetaxel that is causing this elevation. Has anyone else had this side effect and what was prescribed? Btw he has not touched any alcohol or even taken a Tylenol.