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Docetaxel

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DOCETAXEL FATIGUE

I have had 2 rounds of somewhat reduced dose docetaxel. PSA down after the first round which is terrific, but I am trying to wrap my head around the fatigue I am experiencing.
I have had 2 rounds of somewhat reduced dose docetaxel. PSA down after the first round which is terrific, but I am trying to wrap my head around the fatigue I am experiencing.
Arthur479 profile image
Arthur479
in Advanced Prostate Cancer

Following Docetaxel

I read several months ago that some of you went back on Xtandi after chemo failed. Can I get some help on this. I'd like to try Xtandi again if my OC would agree.
I read several months ago that some of you went back on Xtandi after chemo failed. Can I get some help on this. I'd like to try Xtandi again if my OC would agree.
docbulldog profile image
docbulldog
in Advanced Prostate Cancer

How to cope and combat Docetaxel side effects without compromising its effectiveness

Is there are role for Naturopathic therapies to help with se of docetaxel? Does anyone have experience with these practitioners, good or bad? Any suggestions on what I can do to help with my recovery from docetaxel will be helpful and taken seriously. Thank you
Is there are role for Naturopathic therapies to help with se of docetaxel? Does anyone have experience with these practitioners, good or bad? Any suggestions on what I can do to help with my recovery from docetaxel will be helpful and taken seriously. Thank you
Grateful4this profile image
Grateful4this
in Advanced Prostate Cancer
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Docetaxel efficacy

My MO prescribed me docetaxel injections. Does this drug is really powerful to reduce metastases and PSA? Thank you.
My MO prescribed me docetaxel injections. Does this drug is really powerful to reduce metastases and PSA? Thank you.
Catfish21 profile image
Catfish21
in Advanced Prostate Cancer

PEACE1 data now published

Interestingly, docetaxel did not add to the incidence of severe or fatal adverse events.
Interestingly, docetaxel did not add to the incidence of severe or fatal adverse events.
Tall_Allen profile image
Tall_Allen
in Advanced Prostate Cancer

Nivolumab+docetaxel trial

My MO suggested me to participate in Nivolumab/placebo + docetaxel trial, Phase 3. I checked the results of Phase 2, and, honestly, I was not very impressed with results. I found no big difference between effectiveness of this combo and docetaxel only.
My MO suggested me to participate in Nivolumab/placebo + docetaxel trial, Phase 3. I checked the results of Phase 2, and, honestly, I was not very impressed with results. I found no big difference between effectiveness of this combo and docetaxel only.
Catfish21 profile image
Catfish21
in Advanced Prostate Cancer

Nausea after docetaxel

Hello guys, I got my first docetaxel infusion a couple days ago and cannot sleep because of strong nausea. My MO prescribed me ondansetron (8 mg tab on the tongue), but it does not work. Could you educate me how to fight this nausea? Thank you.
Hello guys, I got my first docetaxel infusion a couple days ago and cannot sleep because of strong nausea. My MO prescribed me ondansetron (8 mg tab on the tongue), but it does not work. Could you educate me how to fight this nausea? Thank you.
Catfish21 profile image
Catfish21
in Advanced Prostate Cancer

Keytruda + docetaxel

My MO suggests me to participate in Keytruda+docetaxel trial. I would appreciate if someone could educate me about the effectiveness of such combination. Thanks in advance. Bob.
My MO suggests me to participate in Keytruda+docetaxel trial. I would appreciate if someone could educate me about the effectiveness of such combination. Thanks in advance. Bob.
Catfish21 profile image
Catfish21
in Advanced Prostate Cancer

Docetaxel and headaches?

I had Dexamethasone before and after the Docetaxel but have Prednisolone on normal days.
I had Dexamethasone before and after the Docetaxel but have Prednisolone on normal days.
konichiwa12 profile image
konichiwa12
in Advanced Prostate Cancer

What does ‘oral chemo’ mean

I had my first chemo last week as an infusion of Docetaxel Thanks in advance
I had my first chemo last week as an infusion of Docetaxel Thanks in advance
Brysonal profile image
Brysonal
in Advanced Prostate Cancer

Should Early Use of Chemotherapy Be Avoided in the Treatment of Metastatic Prostate Cancer?

"According to the evidences so far, including this study, docetaxel should be recommended as second-line treatment for metastatic CRPC patients who received first-line ARPI. However, docetaxel is selected as second-line treatment only for limited patients in real-world clinical practice.
"According to the evidences so far, including this study, docetaxel should be recommended as second-line treatment for metastatic CRPC patients who received first-line ARPI. However, docetaxel is selected as second-line treatment only for limited patients in real-world clinical practice.
pjoshea13 profile image
pjoshea13
in Advanced Prostate Cancer

PSA now at 15 time to start a treatment but don’t know which drugs.

How many docetaxel cycles and is there such a thing as low dose docetaxel? Dr Saylor at MGH says time to start lupron Consult at Dana Faber says lupron + abiraterone/prednisone Dr Laccetti at MSK ADT+Abiraterone/prednisone Thank you for your expert opinions
How many docetaxel cycles and is there such a thing as low dose docetaxel? Dr Saylor at MGH says time to start lupron Consult at Dana Faber says lupron + abiraterone/prednisone Dr Laccetti at MSK ADT+Abiraterone/prednisone Thank you for your expert opinions
KocoPr profile image
KocoPr
in Prostate Cancer Network

Daralutamide and Survival in Metastatic, Hormone Sensitive Prostate Cancer

CONCLUSIONS In this trial involving patients with metastatic, hormone-sensitive prostate cancer, overall survival was significantly longer with the combination of darolutamide, androgen-deprivation therapy, and docetaxel than with placebo plus androgen-deprivation therapy and docetaxel, and the addition
CONCLUSIONS In this trial involving patients with metastatic, hormone-sensitive prostate cancer, overall survival was significantly longer with the combination of darolutamide, androgen-deprivation therapy, and docetaxel than with placebo plus androgen-deprivation therapy and docetaxel, and the addition
Graham49 profile image
Graham49
in Advanced Prostate Cancer

ARASENS: Darolutamide + ADT + Docetaxel may become new SOC for mHSPC - from ASCO GU Symposium 2022

CC, reported significant overall survival from 3 ARASENS trial results when compared to placebo + ADT + Docetaxel. A 32% reduction in the risk of death with no increased toxicity (pub. in NEJofM and wrap-up edition of ASCO GU 2022 Symposium).
CC, reported significant overall survival from 3 ARASENS trial results when compared to placebo + ADT + Docetaxel. A 32% reduction in the risk of death with no increased toxicity (pub. in NEJofM and wrap-up edition of ASCO GU 2022 Symposium).
JRPnSD profile image
JRPnSD
in Advanced Prostate Cancer

Another victory for "triplet"therapy for newly diagnosed metastatic men.

All 1,306 patients treated from 2016-2018 were randomized to receive darolutamide (DARO) or placebo (PBO) on top of docetaxel and ADT.
All 1,306 patients treated from 2016-2018 were randomized to receive darolutamide (DARO) or placebo (PBO) on top of docetaxel and ADT.
Tall_Allen profile image
Tall_Allen
in Advanced Prostate Cancer

Starting Xofigo RA 223

My question is - have any of you tried Xofigo after Docetaxel and did you have any luck with it. I am feeling the best I have felt in a year after the chemo. We sure always appreciate all of your input. Thanks - Tom
My question is - have any of you tried Xofigo after Docetaxel and did you have any luck with it. I am feeling the best I have felt in a year after the chemo. We sure always appreciate all of your input. Thanks - Tom
tceinvestments profile image
tceinvestments
in Advanced Prostate Cancer

Where do I go from here?

: 1.Keytruda now (genetic test shows MSI-High) 2.Docetaxel now 3.Maintain status quo (Zytiga + Firmagon) until change in PSA 4.Radiate mets 5.Treat primary MO suggested starting Docetaxel now and save Keytruda until PSA starts rising.
: 1.Keytruda now (genetic test shows MSI-High) 2.Docetaxel now 3.Maintain status quo (Zytiga + Firmagon) until change in PSA 4.Radiate mets 5.Treat primary MO suggested starting Docetaxel now and save Keytruda until PSA starts rising.
davidw777 profile image
davidw777
in Advanced Prostate Cancer

ADT+docetaxel first impressions, adding darolutamide

First dose of docetaxel wasn't too bad. Immediately after infusion I felt fine and could even have driven myself home but took a taxi. Had some headache and tiredness a couple of days later, but that was it.
First dose of docetaxel wasn't too bad. Immediately after infusion I felt fine and could even have driven myself home but took a taxi. Had some headache and tiredness a couple of days later, but that was it.
Oldie68 profile image
Oldie68
in Advanced Prostate Cancer

Adding docetaxel for BCR CSPC at 3-mo doubling rate

Third recommendation is 9 months of ADT + abiraterone + docetaxel. The addition of docetaxel is given the fast doubling rate and the fact that I am otherwise very healthy without symptoms.
Third recommendation is 9 months of ADT + abiraterone + docetaxel. The addition of docetaxel is given the fast doubling rate and the fact that I am otherwise very healthy without symptoms.
PGDuan profile image
PGDuan
in Advanced Prostate Cancer

ARASENS Trial

CONCLUSIONS In this trial involving patients with metastatic, hormone-sensitive prostate cancer, overall survival was significantly longer with the combination of darolutamide, androgen-deprivation therapy, and docetaxel than with placebo plus androgen-deprivation therapy and docetaxel, and the addition
CONCLUSIONS In this trial involving patients with metastatic, hormone-sensitive prostate cancer, overall survival was significantly longer with the combination of darolutamide, androgen-deprivation therapy, and docetaxel than with placebo plus androgen-deprivation therapy and docetaxel, and the addition
Scout4answers profile image
Scout4answers
in Advanced Prostate Cancer
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