Experiences with

Docetaxel

I have had 2 rounds of somewhat reduced dose docetaxel. PSA down after the first round which is terrific, but I am trying to wrap my head around the fatigue I am experiencing.

I read several months ago that some of you went back on Xtandi after chemo failed. Can I get some help on this. I'd like to try Xtandi again if my OC would agree.

Is there are role for Naturopathic therapies to help with se of docetaxel? Does anyone have experience with these practitioners, good or bad? Any suggestions on what I can do to help with my recovery from docetaxel will be helpful and taken seriously. Thank you

My MO prescribed me docetaxel injections. Does this drug is really powerful to reduce metastases and PSA? Thank you.

Interestingly, docetaxel did not add to the incidence of severe or fatal adverse events.

My MO suggested me to participate in Nivolumab/placebo + docetaxel trial, Phase 3. I checked the results of Phase 2, and, honestly, I was not very impressed with results. I found no big difference between effectiveness of this combo and docetaxel only.

Hello guys, I got my first docetaxel infusion a couple days ago and cannot sleep because of strong nausea. My MO prescribed me ondansetron (8 mg tab on the tongue), but it does not work. Could you educate me how to fight this nausea? Thank you.

My MO suggests me to participate in Keytruda+docetaxel trial. I would appreciate if someone could educate me about the effectiveness of such combination. Thanks in advance. Bob.

I had Dexamethasone before and after the Docetaxel but have Prednisolone on normal days.

I had my first chemo last week as an infusion of Docetaxel Thanks in advance

"According to the evidences so far, including this study, docetaxel should be recommended as second-line treatment for metastatic CRPC patients who received first-line ARPI. However, docetaxel is selected as second-line treatment only for limited patients in real-world clinical practice.

How many docetaxel cycles and is there such a thing as low dose docetaxel? Dr Saylor at MGH says time to start lupron Consult at Dana Faber says lupron + abiraterone/prednisone Dr Laccetti at MSK ADT+Abiraterone/prednisone Thank you for your expert opinions

CONCLUSIONS In this trial involving patients with metastatic, hormone-sensitive prostate cancer, overall survival was significantly longer with the combination of darolutamide, androgen-deprivation therapy, and docetaxel than with placebo plus androgen-deprivation therapy and docetaxel, and the addition

CC, reported significant overall survival from 3 ARASENS trial results when compared to placebo + ADT + Docetaxel. A 32% reduction in the risk of death with no increased toxicity (pub. in NEJofM and wrap-up edition of ASCO GU 2022 Symposium).

All 1,306 patients treated from 2016-2018 were randomized to receive darolutamide (DARO) or placebo (PBO) on top of docetaxel and ADT.

My question is - have any of you tried Xofigo after Docetaxel and did you have any luck with it. I am feeling the best I have felt in a year after the chemo. We sure always appreciate all of your input. Thanks - Tom

: 1.Keytruda now (genetic test shows MSI-High) 2.Docetaxel now 3.Maintain status quo (Zytiga + Firmagon) until change in PSA 4.Radiate mets 5.Treat primary MO suggested starting Docetaxel now and save Keytruda until PSA starts rising.

First dose of docetaxel wasn't too bad. Immediately after infusion I felt fine and could even have driven myself home but took a taxi. Had some headache and tiredness a couple of days later, but that was it.

Third recommendation is 9 months of ADT + abiraterone + docetaxel. The addition of docetaxel is given the fast doubling rate and the fact that I am otherwise very healthy without symptoms.

CONCLUSIONS In this trial involving patients with metastatic, hormone-sensitive prostate cancer, overall survival was significantly longer with the combination of darolutamide, androgen-deprivation therapy, and docetaxel than with placebo plus androgen-deprivation therapy and docetaxel, and the addition