Experiences with

Bicalutamide

Hello, Wondering if anyone has just been on bicalutamide by itself (without the hormone injections) as a form of treatment?

Has anyone used Bicalutamide & Dutasteride for keeping localized PCa stable during AS?

One MO says to stop the bicalutamide since starting relugolix and the other MO says to continue bicalutamide along with relugolix Any thoughts

Early in my diagnosis ( approx. 6 years ago) I was on Bicalutamide. It was ineffective and switched to Abiraterone.

Initially the plan was to do lupron and he was started on bicalutamide 100 mg daily , which he took for 3 weeks uptil 7th June. But then we decided to go with relugolix and not lupron and the bicalutamide was stopped. He has been taking only Relugolix from 8th June.

Anyone had similar thoughts or experiences from SARMs in conjunction with Bicalutamide?

I read here some do enzalutamide alone without ADT or bicalutamide alone and have low psa numbers even with their testasterone being very high Whereas for those on ADT and ARSi both they say the testosterone numbers should be low and lower the better. Can someone throw some light on this 😊

[/i] [i] enhances the oxidative circuit initiated by iron[/i] [i]All prostate cancer cells proliferate less when exposed to –iron combination than when exposed to each single treatment.

Bicalutamide mono therapy worked great for nearly three years. PSA <0.1, T~300-400. Starting Dec. 2023 PSA began rising. Tried Lupron Depot in July. PSA has continued to rise. Now at 2.7.

I've requested relugolix instead of bicalutamide/ lupron for ADT, Relugolix is now mandated by NICE in the UK for locally advanced hormone sensitive PC, as of 14th August 2024. So the NHS must ensure that it is being offered as an option.

I am getting nervous after bicalutamide failed in less than 2 years.

He was given bicalutamide for 30 days on June 20th and got his Lupron shot for 3 months. Just have been told he is probably gonna get RT soon. I appreciate any advice

I was on bicalutamide monotherapy three years. My testosterone vas very high (1500) and was surprised why reaserchres and doctors didnt try to lower it. I had not tools to do my own experiment until Orgovyx appeared. Two years ago I was ready to buy Orgowyx in USA but it was impossible.

Initially the plan was to do lupron and he was started on bicalutamide which he took for 3 weeks uptil 7th June. But then we decided to go with relugolix and not lupron.

• My PSA began to rise slowly, and when it reached 1.16 in April 2023, I was placed on Bicalutamide and Orgovyx. However, the PSA continued to increase, prompting my oncologist to replace Bicalutamide with Erleada.

He has no history of any issues with his blood pressure, heart, kidney, or liver and is not on any medications except Lupron, although he was on Bicalutamide for two weeks before Lupron to counter the drug-induced T flares.

Started eligard and bicalutamide post RP in 2018. Followed advice of urologist until 2022. New urologist took me off both after PSA of 0.01. Unfortunately, l did not receive advice about secondary effects of the above drugs-osteoporosis etc.

My Dad , 83 , with bone mets has started bicalutamide since a week and is soon to take the Lupron shot. But he has a fear of injections as many years back he has developed an abscess due to an injection wrongly given. Is orgovyx as effective as the injections in reducing testesterone ?

He has been on bicalutamide since two weeks. He is in good health generally and has not had heart issues apart from hypertension since many years , controlled by medicine. Doctor has advised 3 monthly lupron injections.

I am a little bit uncomfotable about discontinuing bicalutamide and dutasteride.....