Experiences with

Cabazitaxel

He just finished number 3 of Cabazitaxel. anyone have success on Cabazitaxel when Docetaxel failed

Results: Of 373 patients, 14% received cabazitaxel, 65% received 177Lu-PSMA, and 21% received both. “Rates of a prostate-specific antigen decline of at least 50% were 32% versus 0% for 177Lu-PSMA versus cabazitaxel.

Cabazitaxel Question: PSA Started at 81 ( over 60 bone metastases) after 1st chemo dropped 11 points 70 after 2nd chemo it went up 20 points Could this be chemo flare? My dad is also not taking daily prednisone because it messes with his blood sugar (he is diabetic) .

As his PSA is going up, his oncologist wants to try giving chemotherapy again but with cabazitaxel. Has anyone else experienced a similar reaction with docetaxel and were able to successfully undergo a second attempt with cabazitaxel? I’d greatly appreciate any insights or advice. Thank you!

I would like to know if any of you have repeated cabazitaxel after it worked the first time and what results you got.

Anyone have positive experience with Cabazitaxel/Jetvana?

Unfortunately my brother(55 years) failed his treatment with Cabazitaxel and now we are looking for clinical trials. He has done triplet therapy with Nubequa and Docetaxel, Zytiga and prednisone and radiotherapy for his hip and now Cabazitaxel.

I have no idea what I might suggest to my oncologist as a possibility after my upcoming 6th infusion of Cabazitaxel plus Carboplatin. Thanks in advance, Leps

My father is 87 and due to start Pluvicto after doxcetaxel and cabazitaxel. Other than being fatigued and weak from 2.5 years of treatment he is in good health but still requires daily assistance to make sure he doesn’t fall; catheter changes, and dressing.

I've had 7 sessions of Cabazitaxel and around the 4th session, I started to get edema in my legs and feet. It is quite severe, they started me on a diuretic but it does not seem to help much.

Psa 101.68 Doc stopping my treatment of Cabazitaxel and starting Pluvicto. Does anyone have feedback? PSMA scan shows more activity in the bones and lymph nodes.

I plan to be treated with cabazitaxel which has less side effects. I know all individuals have different situations, Appreciate Cabazitaxel users to respond as to edema, hair loss, etc. Thanks.

For people that Docetaxel worked, why do they typically switch you to Cabazitaxel for the 2nd time of chemo instead of repeating the Docetaxel? Thanks.

If you did Cabazitaxel before docetaxel, then let me know what your experience was like. I know Cabazitaxel comes after Docetaxel.

This discovery has placed him out of contention for both Pluvicto and cabazitaxel.

MO suggested cabazitaxel (1st choice) or enzalutamide (discouraged because cancer is aggressive). Any data/experience that combined enzalutamide and cabazitaxel would be better?

The study compares xaluritamig to standard treatments, such as cabazitaxel or a second androgen receptor-directed therapy (ARDT). The trial is enrolling adult patients with mCRPC who meet specific criteria, including prior treatment with at least one ARDT and one taxane therapy.

He completed 6 of 10 Cabazitaxel treatments in July of 2024. Scan in July and scan in Sept showed no changes. He had a PSA taken yesterday and his PSA has more than tripled to 42.9. He has an appointment with the oncologist on monday.

That same day he did the cabazitaxel, a low dose, and has been feeling great since. Minimal side affects except fatigue. His coloring is back to normal and he has no pain at all. He had bloodwork done this week and his PSA went from 395 to 466. We are so grateful he is feeling good but confused.

I'm pretty sure he'll have to go through Cabazitaxel after that and it'll be much harder on him. He tolerates Pluvicto very well outside of some fatigue the first week. Thank you. I hope this treatment works as well for everyone as it did for my father. Please don't give up hope!