I’m kindly asking anyone for advice as to where to go from here. I can’t seem to get ahead, feeling o.k for a couple of days, then down in the dumps for weeks. I presently take Synthroid 112.5 mcg, & 5 mcg cytomel, taken between 7am - 8am. No food nor drinks for at least 3 hours, taken with a full glass of water. I’m very frustrated because I can’t seem to remain stable for more than 2 weeks at a time. I suffer from severe post nasal drip, fatigue, headaches, VERY low moods. Here are my results from November 3, fasting, taken 24 hrs after my last Synthroid & 10 hours after the lat cytomel. No vitamins taken for a week before the test. Tsh: 0.01. (0.32-4.00). FT4: 15 (9-19). Ft3: 4.5 (2.6-5.8). B12, Folate, Ferritin, vitamin D, all are in the upper range done 3 months prior. What do I need to be doing to feel a little better. I’m also not able to loose a pound from the massive weight gain over the past 3 years since my thyroidectomy. My diet is good, I’m only able to walk for 45 minutes due to fatigue. Am I loosing the battle? Some guidance/advice would be much appreciated. Thanks to all who take the time to reply.
Written by
Rosebud1955
To view profiles and participate in discussions please or .
Thanks for your response! I was thinking of adding 2.5 of cytomel but I’m afraid of going over the edge, or should I add another 12.5 of Synthroid.? What would you recommend? Thanks!!
Thanks for reply! Sorry you’re suffering as well. I do suffer from psoriatic arthritis as well. I never thought that such a small gland could be so important, I have never been the same since surgery. The doctors are quick to remove the thyroid, then they abandon us. What a shame!! We’re fortunate to have the support from all the kind and knowledgeable folks on this site.
Thanks for taking the time to reply. I have been dairy free for the past 5-6 years, the post nasal drip started at the same time when my thyroid started to fail, before I started any thyroid hormone. It has gotten worse since my thyroidectomy. My Endo is in agreement to starting NDT but I’m scared to make the change. Although I have these symptoms, I’m still able to function. I’m scared to return to being a couch potato. I’m just afraid that NDT might not agree with me and that I might return to the dark days. What is your opinion on starting NDT? Many thanks!!
I apologise if I've said this before but since you have had a thyroidectomy you have lost your own natural production of T1,T2,T3.T4 and calcitonin of which there is a measurable level of T3 and T4 - said to be about 100 T4 + 10 T3 daily, from a fully functioning working thyroid.
Since you seem to be having difficulties finding a comfortable measure of both T3 and T4 and have an endocrinologist prepared o support you through a trial of Natural Desiccated Thyroid why not give it go ?
NDT contains all the same known thyroid hormones that the human gland secretes and is dried and ground down pigs thyroid referred to as grains. NDT was successfully used to treat hypothyroidism for over 100 years prior to the blood tests, guidelines, and synthetic T3 and T4 options currently available.
You dose to the relied of symptoms and not a blood test or numbers on the computer :
You go low and slow gently increasing in 1/4 grain increments :
No thyroid hormone works well however if your vitamins and minerals are not optimal and these need to be sorted out first, and if this has been going on for a considerable time you might find your adrenals need a bit of support as well.
you have lost your own natural production of T1,T2,
I don't agree with you.
Most T2 in the body is formed by deiodination of T3. The amount of T2 produced is related to the amounts of both T3 and rT3.
The amount available from the thyroid is just about infinitessimal. Yes, a highly sensitive assay of thyroid tissue will find a few molecules of T2 (and T1). But that is far from indicating that the thyroid gland is a source of T2 (and T1).
To be significant, it would have to be at least a reasonable percentage of the amounts formed by deiodination and I do not believe that is the case.
We would also need to see a mechanism by which T2 (and T1) can be transported.
The deiodination of T3 and rT3 occurs within our tissues. All three deiodinase enzymes (D1, D2 and D3) convert to T2. Here's a little diagram (somewhat old and might not include everything that have been found more recently - but accessible):
Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.
Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.