Mums results comments welcome

[Clairewalker751]

CRP 36.34 < 5

Ferritin 291 (13-150)

B12 active 71 >37.5

Vit D 75.3 (50-175)

TSH 0.085 (0.27-4.2)

T3 4.34 (3.1-6.8)

T4 18 (12-22)

Thyroglobulin 790 <115

TPO 401 <34

She's on 125 levo and feels dreadful aged 70 a lot of pain, I suspect she's in the middle of a hashi flare, she doesn't take any supplements any advice welcome

[SeasideSusie Remembering]

Clairewalker751

Her raised CRP and ferritin could be signs of inflammation and Hashi's causes inflammation so could be connected especially as you suspect she's in the middle of a hashi's flare.

Her B12 level could be higher. Below 70 suggests testing for B12 deficiency and 71 is too close for comfort. I like my Active B12 level to be over 100.

Was folate not tested? Folate and B12 work together.

Vit D would also be better at the level recommended by the Vit D Council/Vit D Society which is 100-150nmol/L.

[Clairewalker751 in reply to SeasideSusie]

Thank you seaside Susie, medichecks have stopped doing folate in the finger prick test and as it was difficult to get her to agree to a test at all I stuck with the finger prick, the high ferritin concerns me for Hemochromatosis, but as her inflammation is high is it more likely to be that?

[SeasideSusie Remembering in reply to Clairewalker751]

Clairwalker751

Blue Horizon's Thyroid Premium Gold is an equivalent test and does include folate and can be done by fingerprick - one x 0.8ml microtainer whichi s a tiny bit bigger than Medichecks 0.6ml microtainer. Generous discount code for BH Premium tests here:

thyroiduk.org/getting-a-dia...

the high ferritin concerns me for Hemochromatosis, but as her inflammation is high is it more likely to be that?

I can't say with any absolute certainty but as CRP is high as well then it's a possibility. Inflammation raises both CRP and ferritin.

[fuchsia-pink]

Can she try and get a small increase in levo?

Her free T4 is 60 through range but free T3 is only 1/3 through range. She'd probably feel better with this being higher, and there is plenty of wriggle-room in the T4 before it goes over range ...

[Clairewalker751 in reply to fuchsia-pink]

Her GP has her on 100 I told her to increase to 125 as they are probably only testing TSH I gave her some thyrogold but have told her to hold off until we've checked her levels trouble is she doesn't seem to accept that she's feeling crap due to her Hashis she keeps going to GP with pains and ailments who fobs her off with pain killers which she's taking loads of, I'm going to see her with her results tonight and going to try and get her to focus on managing her Hashis instead of her thinking of believing it's another ailment?

[fuchsia-pink in reply to Clairewalker751]

Good luck! It's rubbish that doctors know so little about thyroid so can't support you properly. She's very lucky to have such a lovely caring daughter

[SlowDragon Administrator]

Is she on strictly gluten free diet?

If not...would she consider trying it

Often gluten causes joint pain

Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten. Dairy is second most common.

According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find gluten free diet helps, sometimes significantly. Either due to direct gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)

Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and slowly lower TPO antibodies

While still eating high gluten diet ask GP for coeliac blood test first or buy test online for under £20, just to rule it out first

healthcheckshop.co.uk/store...?

Assuming test is negative you can immediately go on strictly gluten free diet

(If test is positive you will need to remain on high gluten diet until endoscopy, maximum 6 weeks wait officially)

Trying gluten free diet for 3-6 months. If no noticeable improvement then reintroduce gluten and see if symptoms get worse

chriskresser.com/the-gluten...

amymyersmd.com/2018/04/3-re...

thyroidpharmacist.com/artic...

drknews.com/changing-your-d...

restartmed.com/hashimotos-g...

Non Coeliac Gluten sensitivity (NCGS) and autoimmune disease

ncbi.nlm.nih.gov/pubmed/296...

The predominance of Hashimoto thyroiditis represents an interesting finding, since it has been indirectly confirmed by an Italian study, showing that autoimmune thyroid disease is a risk factor for the evolution towards NCGS in a group of patients with minimal duodenal inflammation. On these bases, an autoimmune stigma in NCGS is strongly supported

ncbi.nlm.nih.gov/pubmed/300...

The obtained results suggest that the gluten-free diet may bring clinical benefits to women with autoimmune thyroid disease

nuclmed.gr/wp/wp-content/up...

In summary, whereas it is not yet clear whether a gluten free diet can prevent autoimmune diseases, it is worth mentioning that HT patients with or without CD benefit from a diet low in gluten as far as the progression and the potential disease complications are concerned

restartmed.com/hashimotos-g...

Despite the fact that 5-10% of patients have Celiac disease, in my experience and in the experience of many other physicians, at least 80% + of patients with Hashimoto's who go gluten-free notice a reduction in their symptoms almost immediately.

[Clairewalker751 in reply to SlowDragon]

Thanks slow dragon, I have tried to talk to her about going gluten free also, I will keep plugging away but ultimately I can't force her to make the changes I think she needs to take

[SlowDragon Administrator in reply to Clairewalker751]

Ask her to try it for a week?