Log in
Thyroid UK
99,623 members113,179 posts

Thyroid Profile results first time test - comments welcome

Before you read

- my wife's results;

- she has all the classic symptoms of hypothyroid;

- she is not on any hypothyroid medication;

- TSH levels a week ago by NHS test were 2.53 therefore the GP sent her away saying nothing - therefore she went and got tested at Medichecks - TSH jumped to 4.5!!! How is this possible? She got tested at the same time of day...

- before we go to a private doctor and spend hundreds of pounds please comment below if it is worth going to one. Thanks!

Thyroid Function


FREE THYROXINE 14.4 pmol/l 12.0 -22.0

TOTAL THYROXINE(T4) 73 nmol/L 59 -154

FREE T3 5.2 pmol/L 3.1 -6.8

Thyroid Antibodies

Thyroglobulin Antibody 11.3 IU/mL 0-115

Thyroid Peroxidase Antibodies 14.8 IU/mL 0 -34



Active B12 79 pmol/L 25.1 -165.0

Folate (serum) 12.0 ug/L > 2.9


Inflammation MarkerCRP -High sensitivity 2.5 mg/l 0.0 -5.0

Iron Status

FERRITIN 56 ug/L 13 -150

Vitamin D - NHS doc said she had low Vitamin D and she has been taking extra supplements for that.


22 Replies


If your wife's TSH remains over range her NHS GP should treat her. If her TSH drops back <3.0 I doubt you will find a private doctor willing to treat until TSH is >3.0. It might be better to wait 3 months and retest before deciding to go private.

Free thyroxine (FT4) isn't unduly low for someone not taking Levothyroxine. Free T3 is good but that is likely to be due to high TSH flogging conversion.

Thyroid antibodies are negative for autoimmune thyroiditis (Hashimoto's).

Active B12 >35 is unlikely to be deficient.

Folate is good.

Ferritin is optimal halfway through range. Your wife could eat more iron rich food to raise ferritin or supplement iron with 1,000mg vitamin C to aid absorption and minimise constipation.

CRP is an inflammation marker. 2.5 doesn't indicate much inflammation.

What was her vitD result and how much has her doctor prescribed?

1 like

Doc didnt diclose her vitamin D levels only that she was deficient. She will talk to the NHS doc when she visits them again.

The NHS GP clinic got results of THS 2.53 just last week and this week it went to THS 4.5 at the medichecks private; do you think the GP will be skeptical to treat her now?

She really needs treatment her lack of energy and insomnia and weight loss problems are severely debilitating...

I cannot believe how much THS jumped! How can this be explained? She had her NHS test at 9am and empty stomach and her Medichecks test 8am empty stomach...



TSH fluctuates according to circadian rhythms so it can fluctuate that much in a day but as your wife tested at the same time of day I don't really know why. healthunlocked.com/thyroidu...

TSH can be elevated due to non-thyroidal illness like a virus or infection which is why I suggested she retest in 2-3 months.

I don't know what your GPs attitude is to private tests, many won't take notice of them, but certainly show them to GP. NHS Lab is likely to decline any request to retest within a month of the last test.

1 like

Thanks for your comments. I really hope the NHS GP will acknowledge the private test results but i guess we shall see.


By the way Clutter, after some research it may have been due to our change in diet that made such a dramatic increase in the THS levels (or at least contribute to it) as we were on a very low carb diet before my wifes first test and a very high carb diet for the second test.

I thought that might interest you as a possible explanation. dietvsdisease.org/low-carb-...

1 like

Found Vit D result

Serum total 25-hydroxy vitamin D level 56.5 nmol/L [70.0 - 150.0]

Below low reference limit

Recommendations for Adult Bone Health: Deficient = <40, Insufficient =

40-70, Replete = 70-150. This method underestimates vitamin D2. If

patient is taking D2 or unknown vitamin D replacement, please request

D2/D3 assay.

Can you decipher?



VitD 56.5 is suboptimal. Optimal is around 100. How much vit D3 is she taking?


Hi Clutter

Bearing in mind above results:

- How much iron supplement would be recommended with 1000mg Vit C daily? (Dont want to up my wifes red meat intake as she has high cholesterol)

- How much magnesium daily would be reccomended to aid Vit D absorption?

- Taking vitamin D post a fatty snack such as a few nuts or cheese should be sufficient to assist in not storing vit D in fat cells?



210mg Ferrous Fumarate will probaly be enough.

I wasn't aware that magnesium aided vitD absorption but 375mcg magnesium daily should be sufficient.

VitD should be taken with the fattiest meal of the day to aid absorption. VitD will be stored in cells because it is fat soluble.

Introduce these supplements at weekly or bi weekly intervals so you can spot the culprit if there are any adverse effects.

1 like

Hi Clutter

We have been informed of the benefits of taking iodine for thyroid health. Can you advise this would assist my wife?

Also she's going to the NHS GP on Friday with private test results showing above change in TSH hopefully they will listen.

Barring a good response from the NHS GP we are considering seeing a private Dr in North London from the list next Tuesday. Do you think above test results with extremely close symptoms of hypothyroidism will prompt private doctor to diagnose and prescribe some treatment or will they just say" test again in a few months to confirm"? We have to be careful because cost of visiting doc is hundred of pounds so we need to be sure it's worth going with tests we have received. Thanks so much really appreciate your advice!



I am very against supplementing iodine unless iodine deficiency has been confirmed.

Iodine used to be given to hyperthyroid patients to reduce FT4 and FT3 and raise TSH so I don't think it is likely to be helpful for someone borderline hypothyroid.


Low vitamin D can be causing insomnia

Low vitamin D can result in low B vitamins too


So adding a vitamin B complex may help too - Igennus b complex is good as it's 2 tablets a day - so can start with just one

What dose vitamin D is your wife taking - hopefully more than the standard 800iu they seem to mainly dole out.

You are entitled to know the test result. How low the result is determines the dose requirements. Look up your local CCG guidelines on vitamin D

When taking vitamin D our need for magnesium inceases so it's a good idea to take magnesium supplements (also good for sleep)


Natural Calm Vitality Magnesium powder is easy to use, cheap and widely available. Start on low dose and build up - can cause diarrhoea if take too much too quick

Vitamindtest.org.uk for £28 postal test


We just got a daily 25mg supplement from Boots pharmacy for vitamin D. She will just ask for that result when she goes in again and I assume then they will do some sort of loading dose but in any event I will post here again for commentary.

Even if you look at vitamin D deficiency symptoms they dont fully match what she has. Her symptoms exactly match hypothyroidism so I'm sure she has that.

Any experience/knowledge of how NHS GPs will take private test results? She got 4.5 THS on private (taken at 8am empty stomach) and 2.53 THS at NHS GP (9am empty stomach) test a week earlier.

Obviously they sent her away on the 2.53 results but the 4.5 they cannot ignore?


They are likely to ignore as antibodies are low so no Hashimoto's

Then often want TSH above 10 before starting treatment

Low vitamin D will be preventing thyroid hormones working

As her vitamin D level improves TSH might rise

Forgot to say - if taking any supplements with biotin in (B complex) then must remember to stop taking 3-4,days before any further tests as biotin can falsely affect test results


You can have Hashimoto's and still have low antibodies- a scan of thyroid might reveal more but NHS unlikely to do. Probably would need to go private

25mg vitamin D is only 1000iu - very unlikely to raise level

"Better You" vitamin D mouth spray comes in 3000iu or 5000iu doses. Get in most health shops or online

Ring receptionist and ask for vitamin D result and range - normally in UK under 50 is low but GP may not treat - but advise you to treat yourself

Under 25 is severe and they should treat with loading dose

Looking for result eventually around 100mnol

1 like

Result was found online in profile at 56.5.

Thanks for advice!


Hi Slow Dragon

Where can you get a scan of thyroid and how much does it cost?

So my wife is going to NHS GP on Friday with private test results hopefully they will listen to her utter pain with hypothyroidism symptoms but if they don't we will go private.

We are looking st a private doctor in London. Do you think with above results and extremely typical close symptoms to hypothyroidism will prompt them to diagnose and prescribe treatment or will they just say "test again in a few months to confirm results"?

I ask because the consultation will be hundreds of pounds so we need to be sure it is actually worth it before going. Thanks so much for your advice!


It looks unlikely that a dr would consider Thyroid is the problem with these results and low antibodies.

Weight loss - has she been fully tested for coeliac? Blood test is very unreliable, needs to be endoscopy after 6 week high gluten diet (called gluten challenge)

Alternatively a functional doctor or nutritionist could run lots of tests - Cyrex tests for food sensitivities and stool tests for gut infections like SIBO candida, etc

Not cheap, but I don't think you are going to get much further with NHS - possibly a gastroenterologist. NHS does not offer Cyrex tests

Info about Cyrex tests from well known nutritionist website


SIBO symptoms include weight loss







It doesnt seem like she has SIBO because she is TOTALLY UNABLE to lose weight no matter how hard she tries and this is after she has put on 30kg or so so its really bad now.

But Candida could be something as her gut and her constipation are bad and other symptoms seem to match. Either way we are getting desperate as she sleeps/lies in bed all day and gets serious insomnia and she is exhausted, anxious, panicky and depressed all the time with other weird things like high cholesterol, irregular menstruation cycles, constipation, diarhea.

Vitamin D is low (56.5) and we are treating with vit D and magnesium and also getting iron back up to optimal level but these can't alone explain these symptoms. There is clearly something SERIOUSLY wrong with her and we need answers.



She doesn't need a loading dose of vitD but she needs more than 25mg which is only 1,000iu. I recommend 5 x 25mg for 6 weeks then reduce to 2 or 3 x 25mg daily and retest in April.


Found the vitamin D result:

Serum total 25-hydroxy vitamin D level 56.5 nmol/L [70.0 - 150.0]

Below low reference limit

Recommendations for Adult Bone Health: Deficient = <40, Insufficient =

40-70, Replete = 70-150. This method underestimates vitamin D2. If

patient is taking D2 or unknown vitamin D replacement, please request

D2/D3 assay.

What does this mean?


Well old vitamin D supplements used to be D2, now not used or recommended so you can ignore that

56.6 is insufficient (40-70) - or not very low - GP not obliged to treat

3000iu daily for 2-3 months would probably be enough - important to retest - via £28 test is cheapest

Keep spray next to breakfast stuff and just one spray daily 5-10 mins after breakfast

We must not take too much - it's oil based and body can not get rid of excess

Would still recommend adding Magnesium- very calming and relaxing (as long as no kidney issues) Take Magnesium in evening about an hour before bed

Only ever start one supplement or change at a time and wait 7-10 days before adding another. That way can assess if improvement or not

1 like

The recommended level for Vit D, according to the Vit D Council, is 100-150nmol/L.

Your wife is taking 25mcg (not mg) which is equal to 1000iu and is barely a maintenance dose for someone with a decent level.

Boots own brand (plus H&B and supermarket own brand) contains a lot of cheap rubbish that we don't need ie

Calcium Carbonate, Cellulose, Maltodextrin, Acacia, Sucrose, Maize Starch, Magnesium Stearate, Silicon Dioxide, Triglycerides, Vitamin D3 (Cholecalciferol), Antioxidant (Tocopherol).

Ditch them and buy a decent softgel that contains oil to help absorption, like these - just two ingredients and no unnessary rubbish bodykind.com/productsearch/...

My suggestion would be to start on something like 4000iu daily, even 5000iu, until she reaches the recommended amount, then she'll need a sensible maintenance dose which may be 2000iu daily, it's trial and error so it's recommended to retest once or twice a year to keep within the recommended range. You can do this with a private fingerprick blood spot test with City Assays vitamindtest.org.uk/

There are important cofactors needed when taking D3


D3 aids absorption of calcium from food and K2-MK7 directs the calcium to bones and teeth where it is needed and away from arteries and soft tissues where it can be deposited and cause problems.

D3 and K2 are fat soluble so should be taken with the fattiest meal of the day, D3 four hours away from thyroid meds.

Magnesium comes in different forms, check to see which would suit you best and as it's calming it's best taken in the evening, four hours away from thyroid meds


Check out the other cofactors too.

Your GP wont know any of this, they're not taught nutrition and attach very little, if any, importance to supplements.


You may also like...