I have just had my results back from thriva and my GP. (Unfortunately thriva couldn't process my thyroid test, but I have results from my GP).
For underactive thyroid I have been on 50mg and have not been bumped up to 75mg which I havent yet started taking.
I chose to do the full works with thriva just to see where I was at and if I needed to make any changes. Most things came back fine except for vit D (I will be taking a supplement for this) and CRP, which indicates I have inflammation somewhere in my body.
My question is, has anyone else with an underactive thyroid had raised CRP levels as well? Is it thyroid related?
I have read online that it can be triggered by autoimmune diseases such as lupus, rheumatoid arthritis, certain types of inflammatory bowel disease, chron's, ulcerative colitis and cancers.
I have an intolerance to gluten (blood tests suggest so, along with symptoms). I am awaiting the biopsy to confirm or give further information. Would this potentially be a cause for elevated CRP?
What are your experiences with elevated CRP if any?
Is there a need to contact my GP about it?
My results:
T4 15 Range 11.50 -22.70pmol/L
TSH 5.85 0.55-4.74mu/L
B12 84 37.5-188pmol/L
Folate 21.9 8.83-40nmol/L
Ferritin 38 13-150umol/L
Vit D 69 50-175nmol/L
HBA1C 31 20-42mmol/mol
CRP 3.34 0-3mg/L
Cholesterol and liver are both optimal as well.
Thank you for taking the time to read and for any advice.
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EKTan
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Most things came back fine except for vit D (I will be taking a supplement for this)
Ferritin 38 13-150umol/L
Your ferritin is not fine, it is low. Ferritin is recommended to be half way through range, which is 82 with that range.
You can help raise your level by eating liver regularly, maximum 200g per week due to it's high Vit A content, also liver pate, black pudding, and including lots of iron rich foods in your diet
You're looking at a dose of D3 of about 3,500-4,000iu daily, along with D3's important cofactors Vit K2-MK7 and magnesium. Retest in 3 months. Aim for the level recommended by the Vit D Council and Vit D Society, 100-150nmol/L, once you've reached that you'll need a maintenance dose of possibly 2,000iu, maybe more or less, you'll need to experiment to find your maintenance dose. Retest twice a year when supplementing with D3.
Your TSH is more of a concern especially as you indicate you are taking Levothyroxine. Someone with more knowledge I’m sure will give you further information but my understanding is you need to be below or at the bottom of range.
The CRP result is only just above normal and a repeat could see it back within range. It shows body reacting to any inflammation so could even be an insect bite or small cut.
Your CRP is not that high mine has been 9 and was like that for several years. It indicates there is inflammation somewhere in the body and I think mine is my thyroid because I have a multi-nodular goitre which is under attack because my anti-bodies are very high. I was advised to take selenium to try to lower my anti-bodies which I did. My last test showed my CRP had come down to about 5 but my antibodies are still high at 4000. Having said that I feel well at the moment.
If antibodies are high this is Hashimoto's, (also known by medics here in UK more commonly as autoimmune thyroid disease).
Hashimoto's frequently affects the gut and leads to low stomach acid and then low vitamin levels
Low vitamin levels affect Thyroid hormone working
Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten intolerance. Second most common is lactose intolerance
According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find strictly gluten free diet reduces symptoms, sometimes significantly. Either due to gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)
Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and slowly lower TPO antibodies
While still eating high gluten diet ask GP for coeliac blood test, or buy test online BEFORE trying strictly gluten free diet
Assuming test is negative you can immediately go on strictly gluten free diet
If coeliac test is positive you will need to remain on high gluten diet until endoscopy, with maximum 6 weeks wait, officially
Trying strictly gluten free diet for 3-6 months
If no noticeable improvement, reintroduce gluten and see if symptoms get worse
The aim of Levothyroxine is to increase the dose slowly in 25mcg steps upwards until TSH is under 2 (many patients need TSH significantly under one) and most important is that FT4 is in top third of range and FT3 at least half way through range
NHS guidelines on Levothyroxine including that most patients eventually need somewhere between 100mcg and 200mcg Levothyroxine.
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CRP level elevated can anyone advise.
Can underactive thyroid cause low lymphocyte count and folate levels?
Test Results - Underactive Thyroid
Raised CRP and Ferritin - Thyroid levels ‘in range’
Underactive thyroid and Gluten free
