CRP level elevated can anyone advise. - Thyroid UK

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CRP level elevated can anyone advise.

Mazmilly profile image
21 Replies

Hi

Just wanted Clarification please. I wrote post a few weeks ago with my latest labs results and want to thank all who gave me brilliant advice. My C reactive protein was 9, on the printout of test results it stated "Abnormal but expected". Not sure why this would be. I know that CRP is an inflammation marker would the high cholesterol cause this?

Thank you

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Mazmilly profile image
Mazmilly
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21 Replies
greygoose profile image
greygoose

No, high cholesterol doesn't cause anything. It's being hypo that causes inflammation. :)

Mazmilly profile image
Mazmilly in reply togreygoose

Thank you so much for clearing that up for me I really appreciate it😊

greygoose profile image
greygoose in reply toMazmilly

You're very welcome. :)

Blueskyyy profile image
Blueskyyy in reply togreygoose

Can you be more specific?

You mean the inflammation is because of the antibodies attacking the thyroid?

greygoose profile image
greygoose in reply toBlueskyyy

TPO/Tg antibodies do not attack the thyroid. But, the OP doesn't have high antibodies, anyway. No, it's just the fact of having low thyroid hormone. :)

Blueskyyy profile image
Blueskyyy in reply togreygoose

You didn’t understand my question

Again, according to you, what is the reason of high crp in hypothyroidism patients ?

greygoose profile image
greygoose in reply toBlueskyyy

Oh, I think I did understand your question. Maybe you didn't understand my answer. Not having the right amount of thyroid hormones in your body can cause all sorts of problems, one of them being high levels of inflammation.

Blueskyyy profile image
Blueskyyy in reply togreygoose

I never heard that imbalance in thyroid hormones cause inflammation!

humanbean profile image
humanbean in reply toBlueskyyy

One very common effect of being hypothyroid is that stomach acid levels decrease. This allows all sorts of bugs - bacteria, viruses, yeasts, fungi etc - to take up residence in the small intestine, and increases the risk of developing leaky gut. (The small intestine is supposed to be practically sterile. The microbiome is supposed to remain contained within the large intestine.) All sorts of particles can end up escaping the digestive system, increasing the risk of all sorts of autoimmune problems. All of these cause or increase the risk of inflammation.

Another common effect of low stomach acid is poor absorption of nutrients from the diet. Low nutrients can also lead to inflammation.

It is these common problems that arise in hypothyroidism that make so many people on this forum go on about diet and gut health so much. So many symptoms lead directly or indirectly from low stomach acid.

Another couple of sites that are affected by hypothyroidism is the lungs and the joints, also both classical sites of inflammation.

Every single cell in the body needs thyroid hormone to function properly. If there is insufficient thyroid hormone for cells to work properly then anything can go wrong. This is why the lists of possible symptoms for hypothyroidism are so very, very long.

greygoose profile image
greygoose in reply toBlueskyyy

Well, we learn something new every day! :)

SlowDragon profile image
SlowDragonAdministrator

Your TSH was extremely high at over 9 on Levothyroxine on 175mcg Levothyroxine

Have you had dose increase in Levothyroxine

Probably need referral to endocrinologist

Do you Always take Levo on empty stomach and then nothing apart from water for at least an hour after.

Many take Levothyroxine early morning, on waking, but it may be more convenient and possibly more effective taken at bedtime.

verywell.com/should-i-take-...

ALL Other medication at least 2 hours away, some like HRT, iron, calcium, vitamin D or magnesium at least four hours away from Levothyroxine

Many people find Levothyroxine brands are not interchangeable.

Once you find a brand that suits you, best to make sure to only get that one at each prescription.

Watch out for brand change when dose is increased or at repeat prescription.

Many patients do NOT get on well with Teva brand of Levothyroxine. Though it is the only one for lactose intolerant patients. Teva is the only brand that makes 75mcg tablet.

High cholesterol is highly linked to you being under treated wIth such high TSH and still hypothyroid

nhs.uk/conditions/statins/c...

If you have an underactive thyroid (hypothyroidism), treatment may be delayed until this problem is treated. This is because having an underactive thyroid can lead to an increased cholesterol level, and treating hypothyroidism may cause your cholesterol level to decrease, without the need for statins. Statins are also more likely to cause muscle damage in people with an underactive thyroid.

Mazmilly profile image
Mazmilly in reply toSlowDragon

I have been on the increased dose of 200 mcgs of thyroxine for 5 weeks now and also the 50.0000 iu of vit d. Prior to finding this forum I didn't realise the factors involved with how I took my meds but now I know I have followed all advice. I have only ever been on teva brand had them for 10 years. I really am not feeling any improvement in my symptoms although it is probably still early days after dose increase. I am still experiencing widespread pain and am very low and emotional. I have not taken the cholesterol meds the doctor prescribed.

Thank you again for your advice.😊

SlowDragon profile image
SlowDragonAdministrator in reply toMazmilly

The fact you are on Teva and on relatively high dose of Levothyroxine suggests you might be lactose intolerant

Teva is the only lactose free Levothyroxine tablets in UK

Are you on dairy free or lactose free diet?

Or ever tried this

Lactose intolerance is very common with Hashimoto's

ncbi.nlm.nih.gov/pubmed/240...

Lactose intolerance was diagnosed in 75.9 % of the patients with HT

read.qxmd.com/read/24796930...

These findings show that lactose intolerance significantly increased the need for oral T4 in hypothyroid patients.

Mazmilly profile image
Mazmilly in reply toSlowDragon

No I have not gone lactose free yet I have just read the links you have sent me and it seems very possible that I am intolerant due to me not responding well to levo so I will definitely try to cut lactose from my diet.

Thank you 😊

Lora7again profile image
Lora7again in reply toMazmilly

I am not anything free but when I was on holiday 3 weeks ago I had a lovely cream tea. I then had an upset tummy which I though was caused by the clotted cream being off... now my daughter also had the clotted cream and was fine. I am starting to think perhaps I am?!?

SlowDragon profile image
SlowDragonAdministrator in reply toMazmilly

This explains more about lactose

thyroidpharmacist.com/artic...

Mazmilly profile image
Mazmilly in reply toSlowDragon

Thank you so much for the link. I have downloaded the diet book

Lora7again profile image
Lora7again in reply toMazmilly

I have a crp of 9.1 and have Graves' Disease

Mazmilly profile image
Mazmilly in reply toLora7again

Hi I have been reading your posts and am sorry to see that you are suffering so badly. I really hope you get the treatment you need to feel better. I am under active at the moment and like you am just praying that I will feel better soon. I can't praise this forum enough and the people who have given me such helpful advice they are so much more knowledgeable than any doctor I have seen so far. Fingers crossed for better health soon for both of us take care😊

humanbean profile image
humanbean

Mazmilly, if you are lactose intolerant it could be an issue for you which is anywhere from minor to severe. One simple thing you could try before eliminating lactose from your diet is buying lactase supplements. Lactase is the enzyme required by the body for digesting lactose, a milk sugar. Lactase supplements can be bought from places like Holland & Barrett and sites selling supplements e.g. Amazon, Ebay, HealthMonthly. You would have to find out the dosage you needed when you ate food containing lactose, and always start low.

Be aware that lactase can have some unexpected effects on the digestive system. When I tried it I got (painless) diarrhoea. But I don't regret trying it - it was a simple self-test to do.

Obviously, if you get some benefit from lactase supplements you then have to decide whether or not to continue them or whether to give up eating foods containing lactose.

LAHs profile image
LAHs

Tevo, according to many previous posts here, seems to be a really lousy brand, you might want to think about switching to a better brand. Secondly if you are on a whopping big dose of any T4 but not producing T3 (and therefore feeling ill) then get a blood test for your selenium. Selenium is the catalyst for the T4 to T3 reaction and if your selenium is low you will not produce T3. So, there you are, you have two major problems, you have to decide which one to tackle first. I recommend measuring selenium first (it's simpler) changing brands of T4 to one which works could take a long time.

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