Vitamins and minerals: Hi I have vitamin and... - Thyroid UK

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Vitamins and minerals

Jemma19 profile image
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Hi I have vitamin and mineral levels, here, I have high TSH and high TPO/TG which I am to discuss with GP later today and I am not on any treatment for anything. Symptoms are tiredness, broken sleep, sweating, dry skin, bone pain, feeling cold, weight gain. I am wondering what I need to do next?

Taking 800iu vitamin D on prescription since 2014 thanks in advance.

Ferritin 27 (30 - 400)

MCV 78.8 (80.0 - 98.0)

MCHC 376 (310 - 350)

Haemoglobin estimation 117 (115 - 150)

MCH 28.2 (28.0 - 32.0)

Platelet count 254 (140 - 400)

Haematocrit 0.390 (0.370 - 0.470)

Neutrophil count 0.2 (0.0 - 0.5)

Monocyte count 0.5 (0.2 - 0.8)

Lymphocyte count 1.4 (0.5 - 2.0)

Basophil count 0.0 (0.0 - 0.2)

Eosinophil count 0.2 (0.0 - 0.5)

Iron 6.8 (6.0 - 26.0)

Transferrin saturation 14 (10 - 30)

Folate 2.29 (2.50 - 19.50)

Vitamin B12 262 (190 - 900)

Vitamin D total 28.8 <25 severe vitamin D deficiency. Patient may require pharmacological preparations....25 - 50 vitamin D deficiency. Supplementation is indicated....50 - 75 vitamin D may be suboptimal, and long-term may lead to clinical effects. Advise on safe sun exposure and diet. Supplementation may be indicated....>75 adequate vitamin D)

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Jemma19

Ferritin 27 (30 - 400)

MCV 78.8 (80.0 - 98.0)

MCHC 376 (310 - 350)

Haemoglobin estimation 117 (115 - 150)

MCH 28.2 (28.0 - 32.0)

You have below range ferritin and your other results point to iron deficiency anaemia. You should discuss this with your GP and ask him to follow the local area guidelines for treatment. NICE Clinical Knowledge Sumary for iron deficiency anaemia treatment (which will be very similar to your local area guidelines):

cks.nice.org.uk/anaemia-iro...

Have a read through but this is the treatment:

How should I treat iron deficiency anaemia?

•Address underlying causes as necessary (for example treat menorrhagia or stop nonsteroidal anti-inflammatory drugs, if possible).

•Treat with oral ferrous sulphate 200 mg tablets two or three times a day. ◦If ferrous sulphate is not tolerated, consider oral ferrous fumarate tablets or ferrous gluconate tablets.

◦Do not wait for investigations to be carried out before prescribing iron supplements.

•If dietary deficiency of iron is thought to be a contributory cause of iron deficiency anaemia, advise the person to maintain an adequate balanced intake of iron-rich foods (for example dark green vegetables, iron-fortified bread, meat, apricots, prunes, and raisins) and consider referral to a dietitian.

• Monitor the person to ensure that there is an adequate response to iron treatment.

It would be best if you could have an iron infusion so ask for one, but you may only be prescribed tablets which will take months to raise your level whereas an infusion will raise your level within 24-48 hours.

Take each iron tablet with 1000mg Vitamin C to aid absorption and help prevent constipaton. Always take iron 4 hours away from thyroid meds and two hours away from other medication and supplements as it will affect absorption.

**

Folate 2.29 (2.50 - 19.50)

Vitamin B12 262 (190 - 900)

You are folate deficient with low B12. Do you have any signs of B12 deficiency b12deficiency.info/signs-an... If so take these results, signs of B12 deficiency, and ferritin/iron information and post on the Pernicious Anaemia Society forum here on Health Unlocked for further advice then discuss with your GP healthunlocked.com/pasoc

If no signs of B12 deficiency you need your B12 level increasing as it's generally said that anything under 500 can cause neurological problems. Also, I have read (but not researched) that BCSH, UKNEQAS and NICE guidelines recommend:

"In the presence of discordance between test results and strong clinical features of deficiency, treatment should not be delayed to avoid neurological impairment."

And an extract from the book, "Could it be B12?":

"We believe that the 'normal' serum B12 threshold needs to be raised from 200 pg/ml to at least 450 pg/ml because deficiencies begin to appear in the cerebrospinal fluid below 550".

"For brain and nervous system health and prevention of disease in older adults, serum B12 levels should be maintained near or above 1000 pg/ml.

That's good enough for me and I keep mine around 1000. Sublingual methylcobalamin lozenges are what's needed to supplement B12 yourself and a B Complex is also needed to balance all the B vitamins.

**

Vitamin D total 28.8 Taking 800iu vitamin D on prescription since 2014

You need to discuss his with your GP and ask him has he not noticed that even though you have been supplementing D3 for 3 years you are still in the Deficiency category.

The recommended level is 100-150nmol/L according to the Vit D Council.

800iu D3 isn't going to ever raise your level. It is hardly a maintenance dose for someone with a reasonable level.

NICE treatment summary for Vit D deficiency:

cks.nice.org.uk/vitamin-d-d...

Treat for vitamin D deficiency if serum 25-hydroxyvitamin D (25[OH]D) levels are less than 30 nmol/L.

For the treatment of vitamin D deficiency, the recommended treatment is based on fixed loading doses of vitamin D (up to a total of about 300,000 international units [IU]) given either as weekly or daily split doses, followed by lifelong maintenance treatment of about 800 IU a day. Higher doses of up to 2000 IU a day, occasionally up to 4000 IU a day, may be used for certain groups of people, for example those with malabsorption disorders. Several treatment regimens are available, including 50,000 IU once a week for 6 weeks (300,000 IU in total), 20,000 IU twice a week for 7 weeks (280,000 IU in total), or 4000 IU daily for 10 weeks (280,000 IU in total)."

Each Health Authority has their own guidelines but they will be very similar. Go and see your GP and demand that he treats you according to the guidelines and prescribes the loading doses. Once these have been completed you will need a reduced amount to bring your level up to what's recommended by the Vit D Council and then you'll need a sensible maintenance dose which may be 2000iu daily, it's trial and error so it's recommended to retest once or twice a year to keep within the recommended range. You can do this with a private fingerprick blood spot test with City Assays vitamindtest.org.uk/

There are important cofactors needed when taking D3 vitamindcouncil.org/about-v...

D3 aids absorption of calcium from food and K2-MK7 directs the calcium to bones and teeth where it is needed and away from arteries and soft tissues where it can be deposited and cause problems.

D3 and K2 are fat soluble so should be taken with the fattiest meal of the day, D3 four hours away from thyroid meds.

Magnesium comes in different forms, check to see which would suit you best and as it's calming it's best taken in the evening, four hours away from thyroid meds naturalnews.com/046401_magn...

Check out the other cofactors too.

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