I got my test results back from BH. Could someone please help me decipher them/give me some advice? Thanks
Ferritin72.020 - 150ug/L
TSH2.140.27 - 4.20mIU/L
T4 Total93.064.5 - 142.0nmol/L
Free T4L11.8612 - 22pmol/L
Free T34.123.1 - 6.8pmol/L
Vitamin B12L 79Deficient <140pmol/L
Insufficient 140 - 250
Consider reducing dose >725
Serum FolateL 4.948.83 - 60.8nmol/L
These are the doctors comments:
The vitamin B12 level is low. Some experts believe levels of 400-500 are desirable and that levels below this may lead to symptoms. Low Vitamin B12 levels can lead to Pernicious Anaemia (PA), a state of deficiency of the red blood cells in which there is reduced quality and number. Characteristically, the red blood cells are enlarged in this state (if the deficiency is severe and longstanding). A Full Blood Count is needed to check for this state, which is known as megaloblastic anaemia. Vitamin B12 is commonly found in many foods, particularly meats. Deficiency can develop if intake of the vitamin is reduced or if absorption from the gut is impaired. Poor absorption owing to a deficiency of Intrinsic Factor (IF) is the underlying reason for PA. Vitamin B12 deficiency in the longer run can lead to nervous system disorders - with sensation changes, loss of power or co-ordination, gut disorders and (rarely) dementia or mental illness. Lower level deficiency has been associated with a range of symptoms such as fatigue, memory impairment, irritability, depression and personality changes. Please discuss this finding with your usual doctor, supplementation would be advisable.
The Folate level is low. Folate (Folic acid or Vitamin B9) is one of the B group of vitamins, found in green vegetables in particular. The body's reserves of Folate, unlike Vitamin B12, are low and only sufficient for about four months. Causes of deficiency include reduced intake from the diet or from poor absorption through the gut; increased demand for folate (for example, pregnancy) and side effects of some medication (for example, methotrexate). Symptoms of deficiency include fatigue, mild sensation changes and depression. Prolonged lack of Folate results in megaloblastic anaemia (a red blood cell deficiency in which the cells are characteristically large). Supplementation would be advisable - I advise you to discuss this result with your usual doctor.
The free T4 level is low. In the presence of a normal thyroid stimulating hormone level (TSH), and normal free T3 level it would not surprise me to learn you are taking liothyronine (T3) instead of levothyroxine - is this the case? If you are taking a form of thyroxine medication already, you may need to adjust your dose – a discussion with your usual doctor would be sensible. If not, I also suggest you make an appointment to see your doctor – at least surveillance of thyroid function would be wise, as it would seem in this scenario that an underactive thyroid gland might be developing.
The CRP is raised. A high CRP (C reactive protein) is associated with inflammation from some cause (as seen for example with arthritis or infection). It is not an exact test, and is nonspecific. An elevated CRP is not a normal finding and its presence should lead to further investigation to establish the cause. If you have any symptoms suggesting either infection (cough, fever, urinary symptoms etc) or inflammation (swollen painful joints or generalised aching, for example) is present, I advise you to speak to your doctor soon. In any event a discussion with your doctor in due course would be sensible.