My wife has diagnosed Hashimoto's with TPO antibodies ranging from 116 Iu/ml (6 Jan 2017) to 146 (22 Jul 2016) and TSH ranging from 4.78 Iu/mL (6 Jan 17) to 6.010 (22 July). She started supplementing with Selenium, Zinc, Vitamin D3, and some other adrenal support and B-vitamins at our functional medicine doctors suggestions. I've been researching potentially other supplements and herbs with clinical evidence of success. She went Gluten free as well after diagnosis which might explain some of the improvement in her numbers. We are vegans. She also has slightly low platelets which might be another autoimmune issue (ITP). She did have an ultrasound of her Thyroid which was slightly abnormal - small nodules. They recommended another US in one year.
She is currently not taking any Synthroid since she doesn't have a lot of symptoms other than slight fatigue.
Just the other day I stumbled upon an article discussing a double blind randomized clinical trial testing selenium alone or selenium in combination with myo inositol.
The published results...
Patients were randomized into 2 groups with:
Group A = 83 g selenomethionine/day
Group B = 83 g selenomethionine and 600mg of myo-inositol
Thyroid Antibodies Results: At the end of the study whilst thyroid antibodies had reduced significantly in both groups:
Group A (selenium only): TPOAb decreased by 42% and TgAb decreased by 38%.
Group B (selenium + inositol): TPOAb decreased by 44% and TgAb decreased by 48%.
Group A (selenium only): no change in the TSH level.
Group B (selenium + inositol): TSH concentrations significantly decreased in combination treatment group by 31%!
How the Participants Felt:
Has anyone seen this? Curious about everyone's opinion on adding myo inositol to the supplement list in addition to the selenium she's already taking.