Results on NDT: Hi everyone. I have been on NDT... - Thyroid UK

Thyroid UK

137,634 members161,410 posts

Results on NDT

Shonnyuk profile image
16 Replies

Hi everyone.

I have been on NDT now for a littleover a year. I have been OK at 2.5 grains, but recently started feeling very tired. It could be stress (a lot on my shoulders) but I thought I'd better rule out undermedication.

I have no hyper symptoms at all.

I also supplement vit d, omega 3, b12, iron, selenium, zinc, biotin, evening primrose oil.

Here are my results.

Do you think I should reduce? I know TSH will be suppressed and t4 lower on ndt... but am concerned my t3 maybe too high?

Also test was 8am fasting, 24 hours after last dose.

Many thanks

Written by
Shonnyuk profile image
Shonnyuk
To view profiles and participate in discussions please or .
Read more about...
16 Replies
Anthea55 profile image
Anthea55

Just a quick reply because you mention biotin. Biotin is fine, but recent posts on here have shown that it can upset the thyroid blood tests, so I suggest that you stop taking it for 2 or 3 days before your blood tests, then start again after the tests.

Can't find the posts about it at present, maybe someone else can.

Rapunzel profile image
Rapunzel in reply to Anthea55

Here it is Shonnyuk

articles.mercola.com/sites/...

Top spot Anthea55 two heads + the original article's poster are better than one :)

Shonnyuk profile image
Shonnyuk

Thank you both! I'll have a look.

Just wondering can anyone advise on dose? Should I stay as I am?

waltermelondria profile image
waltermelondria

check that microcrystalline cellulose is not your filler. Cellulose may bind to thyroid hormone and can render it unuseable. we had to remove it from my sons NDT and have replaced it with organic white rice flour which seems to be fine.

Anthea55 profile image
Anthea55 in reply to waltermelondria

That's really interesting, watermelondria.

I'd never heard of microcrystalline cellulose, so googled for it. This link says more.

integrativeholistichealth.o...

It's in both Armour and Nature-throid, but doesn't seem to be in WP Thyroid.

Do you think we are all sensitive to it, or just some of us?

waltermelondria profile image
waltermelondria in reply to Anthea55

there's always a canary in the coal mine and my son is probably it. Microcrystalline cellulose has been found, in autopsies of" over the counter" drug addicts, to create systemic granulations - a condition called agiocentric systemic granulomatosis. Of course these addicts don't know they have it, and like sarcoidosis, systemic granulations make you very unwell, and sarcoid is very hard to diagnose. Did the drug addiction kill them or the granulations? I'd prefer not to risk it....

helvella profile image
helvellaAdministratorThyroid UK in reply to waltermelondria

What I found was this:

Our investigation disclosed that in all 3 cases patients surreptitiously injected crushed oral prescription medication.

ncbi.nlm.nih.gov/pubmed/201...

That is, abusers who were injecting oral medicines.

Have you got anything that says the same about microcrystalline cellulose taken as intended - orally?

waltermelondria profile image
waltermelondria in reply to helvella

anything that is ingested can persorb through the gut lining (Ray Peat) leaky gut which is common amongst the hypothyroid population may make this worse. In my sons case granulations could be seen on his abdomen. When the cellulose was removed not only did the granulations disappear, over time, but we were also able to reduce his thyroid medication by a whole grain - from 3.5 grains to 2.5 grains, with exactly the same blood test results afterwards. But as I say, canary in the coal mine he is, having been born with completely no thyroid gland.

hels333 profile image
hels333 in reply to waltermelondria

I had been on Westthroid, then Naturethroid for some 8 years, when I realised I still wasn't optimally treated, despite taking 3 to 3.5 grains daily, and I still had a lot of symptoms.

I researched microcrystalline cellulose and found WP Thyoid doesn't contain this filler.

When I switched to WP Thyroid, I found my symptoms much improved, and it feels like the meds are working much better for me.

It may be that some are more sensitive than others to M. cellulose. I for one do much better on meds that don't contain that filler.

It might be worth Shonnyuk trying WP Thyroid. Good luck.

Hiddledumpling profile image
Hiddledumpling

Hi,have you tried taking your temprature ,first thing in the morning ,just as you wake ,before you get out of bed .If your temprature is lower than normal ,then you may need to up your dose .Try taking your temp every morning for a week .The Stop the Thyroid Madness book has very good advice ,regarding body temprature and how to regulate your dose .Hope this helps

Shonnyuk profile image
Shonnyuk

Hi... thanks for replies. I will look into what fillers they contain.

I do my rising temperature and pulse regularly. They stay stable at 36.6, and around 70 pulse.

fibrolinda profile image
fibrolinda

Have you checked your adrenals? I would start high dose vitamin c with the iron anyway which will help adrenal and add a good multi b to 'even out' the b vitamins. T3 is high but in range and as you dont feel over medicated I wouldn't reduce. My absolutely amateur opinion only 🙂

T4 is low though, kind of surprised its so low on NDT? Hopefully a wise one will advise on that soon.

Shonnyuk profile image
Shonnyuk

Thanks for all your comments.

I think I'm going to remain on 2.5 as I don't feel hyper and I know on 2grains I felt symptoms return very quickly.

I might look into WP once these run out.

I'd expect the t4 to be low on ndt.. I just concentrate on t3 levels.

I'm sure someone will correct me if I wrong here ! :).

Eddie83 profile image
Eddie83

NDT contains T3:T4 at a 1:4 ratio. That sometimes results in this situation, where FT3 is high and FT4 is low. Were I in your position, I would lower NDT a little (say, to 2 grains) and add in a good (GF) brand of T4. This is assuming, of course, that you are on a good supplement program in which you are getting the minerals (especially) that contribute to good T4->T3 conversion. If your conversion is poor, then adding in T4 could cause unwelcome symptoms.

As I learned from personal experience, there is a downside to driving FT3 close to, or slightly over, top of range. You might not feel hyper in the classical sense, but on the other hand, you might feel improvement if you bring your T3 dosage down enough to eliminate near-range-top symptoms like excessive bowel motility.

Shonnyuk profile image
Shonnyuk

Hi

Many thanks for your reply.

I actually decided to reduce dose to 2.25 grains. At 2 grains my ft3 was 4.3, so a little low.

I supplement selenium200mg to help conversion.

Does this seem reasonable ?

Carew profile image
Carew in reply to Shonnyuk

I hope that is 200 micrograms of Selenium!

You may also like...

1st BLOOD RESULT ON NDT

range 2.5-6.0 I took 90mgs of NDT (1.5 grains) for 4 weeks and then took 105mgs (1 and 3/4 grains)...

Results after switching to NDT

on my recent results? I have been slowly raising NDT and feeling much better but I still have some...

First blood results on NDT

my first test results on NDT. I’m currently on 2 and a quarter grains of NDT. I realise that still...

Results help and starting NDT

(6.5-17.00) TSH 0.18 (0.34-5.60) Serum Iron 21.6(5.00-30.40) Serum TIBC 59.6 (44-80) Iron...

Latest results on NDT

were taken over a month ago, only TSH was tested which came back TSH 3.03. (0.35 - 5.5) No other...