I wonder if I might possibly trouble any of you awesome self-empowering endocrinal autodidacts for feedback on my thyroid bloods from Blue Horizon? The range is different but essentially it's the same story as the NHS bloods, that my TSH is elevated to a clinically significant but not extraordinary death's door degree and vice versa for T3 & T4 isn't it? The superfluity of B12 is because I've been supplementing over the last month as I was deficient before, tho' I might reduce it now.
As i relayed before, my symptoms are occasional brainfog, fatigue tho' not flat out exhaustion and low libido, all quite generic and also potentially age-related (I'm 38 1/2 and male) tho' I'm not kidding myself that my sluggish thyroid isn't major factor . Where I am with this is that I'm unsure as to whether I want to become reliant on thyroxine just yet if it's not absolutely essential, after all my body's still producing enough for me not to have some of the more severe symptoms, such as uncontrollable weight-gain and ME-levels of tiredness. Of course, I would very much like to be more peppy and the fact I can't manage sex happily more than once a week and am zonked beyond useless by 9pm isn't exactly optimal, but I don't know if I'm convinced I'm unwell enough at mo' to start mudwrestling with my GP lol. Some of you peeps sound a lot more concrete poorly than me. But then again I'm kinda playing into the GP's (idle) hands by just hanging back until my thyroid really does pack up. Anyhoo, results:
CRP 0.20 <5.0 mg/L
Ferritin 72.6 30 - 400 ug/L
TSH H 4.41 0.27 - 4.20 IU/L
T4 Total L 58.6 64.5 - 142.0 nmol/L
Free T4 12.95 12 - 22 pmol/L
Free T3 4.91 3.1 - 6.8 pmol/L
Anti-Thyroidperoxidase abs 12.9 <34 kIU/L
Anti-Thyroglobulin Abs 17.4 <115 kU/L
Vitamin D (25 OH) 97 Deficient <25 nmol/L
Insufficient 25 - 50
Consider reducing dose >175
Vitamin B12 H 870 Deficient <140 pmol/L
Insufficient 140 - 250
Consider reducing dose >725
Serum Folate 24.87 8.83 - 60.8 nmol/L New Range
The Thyroid Stimulating Hormone (TSH) is elevated. If you are already taking a form of thyroxine, it is possible that that your dose is too low or that you have forgotten to take it on occasion. It may be that an increase in dose is in order - if adjusted it would be sensible to repeat thyroid function (TFT) testing in around 2 months’ time. If you are not taking thyroxine, and this is the first time TSH has been noted to be high, it is possible that 'non-thyroidal illness' or other medication effects are the cause of the elevation. It may be that hypothyroidism (underactive thyroid gland) is about to develop. In these scenarios, it would be advisable to repeat thyroid function tests in 3 months’ time. I would suggest undertaking this repeat test sooner if symptoms develop.
The total thyroxine level is low but is of unlikely significance as the FT4 is within normal range - and this is the more accurate representation of the level of thyroxine in the blood.
The Vitamin B12 level is elevated. This is not likely to represent significant overdose, as B12 is well tolerated by the great majority of people even in very high concentrations (as indeed are most water soluble vitamins). Excess levels are usually a result of supplementation or from following a diet rich in the vitamin. A few exceptions to this rule include those who suffer from a rare hereditary eye complaint known as Leber’s disease. Too much vitamin B12 in these individuals can lead to damage of the optic nerve, which might lead to blindness. Anyone who is allergic to cobalt should also avoid taking vitamin B12 - as the vitamin contains a significant amount of this element. Rarely, high dose supplements or injections of Vitamin B12 cause diarrhoea, itching, blood clotting and allergic reactions. Liver disease and myeloproliferative disease (disorder of the bone marrow) can lead to elevated levels of B12. Some practitioners advocate high doses of Vitamin B12 to help sufferers from Chronic Fatigue Syndrome (CFS) and to combat the development of Alzheimer's disease, amongst other conditions.