Donnyjam, Thyroid peroxidase and thyroglobulin antibodies are positive for autoimmune thyroid disease (Hashimoto's) which has made you hypothyroid. There is no treatment for Hashimoto's but adopting 100% gluten-free diet may reduce Hashi flares and antibodies.
TSH is high and FT4 is low in range. FT3 is adequate, but probably only due to high TSH. The goal of Levothyroxine is to restore euthyroid status and for most this will be when TSH is 1.0 with FT4 in the upper range. If you are symptomatic ask your GP for a dose increase. Read Treatment Options in thyroiduk.org.uk/tuk/about_... Email louise.warvill@thyroiduk.org.uk for a copy of the Pulse article if you would like to show it to your GP.
B12 467 is adequate. 1,000 is optimal. Supplement 1,000mcg methylcobalamin and take a B Complex vitamin to keep the other B vits balanced.
I am not a medical professional and this information is not intended to be a substitute for medical guidance from your own doctor. Please check with your personal physician before applying any of these suggestions.
Donnyjam, a Hashi flare [up] is when the lymphocytes infiltrate the thyroid gland. It destroys thyroid cells which dump hormone and can make you feel temporarily hyperthyroid. Over time loss of cells causes atrophy and the thyroid is unable to produce suficient hormone.
It can be hard to differentiate whether symptoms are hypothyroid or due to Hashimoto's but I'd wager yours are due to undermedication. In any case, being optimally medicated with lower TSH should reduce frequency Hashi flares and improve hypothyroid symptoms.
My symptoms were largely hyperthyroid to start but then spiralled between hyper and hypo. Thyroid levels were unequivocally normal so it had to be Hashimoto's causing symptoms although most doctors deny it. Symptoms resolved after thyroidectomy which cofirmed to me that Hashi's was causing my symptoms.
I am not a medical professional and this information is not intended to be a substitute for medical guidance from your own doctor. Please check with your personal physician before applying any of these suggestions.
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