Thyroid UK
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Thyroid / Adrenal help needed (ex propecia user)


Hoping I can find some help and support here for what seems like a dead end situation Ive got myself into...

Started taking propecia for hairloss for 5 years (1mg a day)

Came off propecia after noticing a significant drop in sex drive and ED

During these 5 years I go from top performing sportsman to lazy and overweight and unmotivated

I breeze through university but then this new found fatigue causes me to take the easy options in life and walk away from my chosen career path

I also develop severe psoriasis during this period while on propecia

I literally go from top performing alpha male to rock bottom

I have been off propecia 5 years and somehow managing to exist with all these symptoms and just get by

Then after training in the gym for 3 months before a holiday to Las Vegas I crash majorly

(was taking grenade fat burners twice a day for 3 months during this period)

I now

- Find it impossible to get up in the mornings my eyes sting and my body is so weak I can barely stand up without assistance

- Can not remember anything and have no concentration

- Can not play any sport as I am out of breath instantly and my body is so weak

- Can not train in the gym as I am then in pain for upto 7 days

- Have no regular digestive routine and am always constipated

- Never ever have morning wood

- Erections are weak and orgasm is almost non existent

- Testicles / penis have shrunk and always feel like they are trying to go inside

- Severe depression and feel like I have lost my personality

Having been to see a private endo he has done the attached tests and also recently and SST for Cortisol which came back normal

He is at a loss and seems completely unaware of any permanent damage caused by Propecia / Finasteride and says maybe I have ME which I feel is a complete cop out

Please can anyone point me in the right direction

Labs I have had done as follows

Total Protein 71 ( 60-80g/l)

Albumin 48 (35-50g/l)

Total Bilrubin 10 (0-21umol/l)

AST 20 (0-37IU/L)

ALT 28 (10-41IU/L)

Prolactin 190 (86-324mu/L)

Oestradiol 46 LOW (99-192pmol/L)

Testosterone 13.3 (9.9-27.8pmol/L)

VitaminB12 424 (180-2000ng/L)

Serum Folate 9.48 (4.6-18.7ug/L)

P3NP 10.4 HIGH (3.3-9.7ug/L) (Liver test to take methetrexate)

SHGB Normal

Vitamin D 138.9 nmol/L

Serum TSH level 2.58 miU/L

Serum prolactin level 273 (86-324mu/L)

Serum FSH level 9.2 (1.50-12.40IU/L)

Serum LH level 4.9 (1.70-8.60IU/L)

Anti Nuclear antibody Normal

SST test for Cortisol has also come back normal

6 Replies

Welcome to the forum, Dannyboy86.

TSH >2.0 indicates your thyroid may be beginning to struggle but you are unlikely to get a diagnosis of hypothyroidism until TSH is over range or FT4 is below range.

It is possible to have B12 deficiency <500 so you may want to supplement 1000mcg methylcobalamin and take a B Complex vitamin. Folate and vitamin D levels are good.

Other results appear to be within range.

I'm afraid I don't know what symptoms may be caused by low oestradiol and high P3NP. It may be worth Googling to see.


I think you should ask your private endo to test :






It's perfectly possible to be hypo without a high TSH, and/or to have antibodies, meaning autoimmune thyroiditis (Hashimoto's disease).

Having said that, Propecia does appear to have a lot of side-effects...


I've been researching infrared saunas which seem to be quite effective in chronic fatigue and detoxing, so might help with energy and getting rid of any propecia remaining in your system:

I've spoken to this company (I have no link to them) and they seem very good:

1 like

When you have a blood test for thyroid hormones, it should be the very earliest possible and fasting. You can drink water. I'm sorry you've had to give up your chosen career because you were unwell.

Others have suggested a Free T3 blood test and if you read down the page on the link below you will see the reason. I'll also give you another link for info:

(your endo could do ones you didn't have)

I am not medically qualified and think you may well be hypothyroid and I'll also give you a link of symptoms.

Also ask Endo to check for thyroid antibodies. If these are present you'd have an Autoimmune Thyroid Disease which is also called Hashimoto's and the most common.

1 like

Hi guys

I have had the test for Hashis and came back normal

My main issue at the moment is waking up so tired its unbearable!

Does anyone have any advice on how I should approach my GP to ask for T3 and T4 as he is pretty dismissive

My mum and sister both have underactive thyroids too

Thanks in advance


Hi Danny(boy)

Whilst youve had some good advice re thyroid, you need to register for another forum which deals with post-finasteride syndrome i.e.:

You should be able to see from my records on HealthUnlocked that I am suffering from the same condition (which has included hypothyroid symptoms and many others like yourself). I believe the solution lies on Swolesource which is managed by others that have recovered and so is a positive forum. Dont visit PFS Foundation website which is largely negative and dont take such negative views to Swolesource.

Good luck.


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