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Small cell lung cancer
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Update: NEPC Treatment
A few people messaged me regarding updates about my dad’s participation in Duke CHAMP trial for small cell/NEPC. He was admitted into trial Dec ‘23 and received 3 immunotherapy infusions until he had a very severe allergic reaction causing intense itching and grade 4 red rash all over his body. He admitted
A few people messaged me regarding updates about my dad’s participation in Duke CHAMP trial for small cell/NEPC. He was admitted into trial Dec ‘23 and received 3 immunotherapy infusions until he had a very severe allergic reaction causing intense itching and grade 4 red rash all over his body. He admitted
antisocialsocialwrkr
in
Advanced Prostate Cancer
5 months ago
Wondering what to do
Hello I have not posted for a while but I wondered if any had any thoughts to help me with my dilemma. I have had 18 rounds of chemo and rucaparib all of which have been successful for a while. I also had surgery in 2020 when I was diagnosed. My last lot of single carbo chemo have me a stable few months
Hello I have not posted for a while but I wondered if any had any thoughts to help me with my dilemma. I have had 18 rounds of chemo and rucaparib all of which have been successful for a while. I also had surgery in 2020 when I was diagnosed. My last lot of single carbo chemo have me a stable few months
BadgerBright
in
My Ovacome
3 months ago
Shirley
I MBC that had spread to bones now found two small spots on lungs. I was taking ansezole for estrogen blocker and venezico .I am ER statuses positive , HER2 negative. They say I have mutation on my cancer an wants me take a treatment PIQKAY and Fulvestrant. I am very nervous taking these. ANYONE
I MBC that had spread to bones now found two small spots on lungs. I was taking ansezole for estrogen blocker and venezico .I am ER statuses positive , HER2 negative. They say I have mutation on my cancer an wants me take a treatment PIQKAY and Fulvestrant. I am very nervous taking these. ANYONE
Moonfry
in
SHARE Metastatic Breast Cancer
3 months ago
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PSA relapse rate vs testosterone nadir - 3
This plot shows the PSA relapse rate after RT and ADT, for Intermediate and High Risk men, comparing different levels of testosterone nadir ( 50 nd/dL). (ref: 2019) The
best
outcomes
are significantly associated with a
lower testosterone nadir ( < 20 ng/dL),
and the relationship
This plot shows the PSA relapse rate after RT and ADT, for Intermediate and High Risk men, comparing different levels of testosterone nadir ( 50 nd/dL). (ref: 2019) The
best
outcomes
are significantly associated with a
lower testosterone nadir ( < 20 ng/dL),
and the relationship
janebob99
in
Advanced Prostate Cancer
7 months ago
Testosterone back to normal
I was diagnosed with PC last April 2023 with PSA of 125. Darilutimide and Relogolix, along with HIIT, plant based diet, and various supplements brought it down to .006. My MO granted a holiday about 6-7 weeks ago, and yesterday, I had my testosterone score. It is back to 312, which is above the number
I was diagnosed with PC last April 2023 with PSA of 125. Darilutimide and Relogolix, along with HIIT, plant based diet, and various supplements brought it down to .006. My MO granted a holiday about 6-7 weeks ago, and yesterday, I had my testosterone score. It is back to 312, which is above the number
Cape1
in
Advanced Prostate Cancer
7 months ago
Triplet and now Radiation?
Hi all - just wanting your thoughts on this. In my profile you would see full details but I will summarize here. 50yr old diagnosed Aug 2nd with PCA with spread to L5 and pubic bone. Original PSA was around 9 and put on Casodex for month, then Lupron every 3 months, plus Darolutamide. Just completed
Hi all - just wanting your thoughts on this. In my profile you would see full details but I will summarize here. 50yr old diagnosed Aug 2nd with PCA with spread to L5 and pubic bone. Original PSA was around 9 and put on Casodex for month, then Lupron every 3 months, plus Darolutamide. Just completed
Yzinger
in
Advanced Prostate Cancer
7 months ago
No more enzalutamide: docetaxel next up
So enzalutamide has stopped doing its thing. PSA up to 3.9 but it’s worked for 3.5 years. Also got a new lesion in my thoracic spine so in addition to docetaxel, a single dose of radiotherapy. Hope that will all be underway within a couple of weeks. Some fear for a while about the meds not working and
So enzalutamide has stopped doing its thing. PSA up to 3.9 but it’s worked for 3.5 years. Also got a new lesion in my thoracic spine so in addition to docetaxel, a single dose of radiotherapy. Hope that will all be underway within a couple of weeks. Some fear for a while about the meds not working and
FortyWinks
in
Advanced Prostate Cancer
7 months ago
Carboplatin alternatives
I was diagnosed with Primary Peritoneal high grade serous cancer stage 3C in early 2021. I had 6 cycles of Carboplatin and Paclitaxel, radical surgery, two more chemo cycles then Niraparib for just over a year until it stopped working and my CA125 began to rise rapidly. Surgery was considered and
I was diagnosed with Primary Peritoneal high grade serous cancer stage 3C in early 2021. I had 6 cycles of Carboplatin and Paclitaxel, radical surgery, two more chemo cycles then Niraparib for just over a year until it stopped working and my CA125 began to rise rapidly. Surgery was considered and
Alice77
in
My Ovacome
7 months ago
Thyroid private blood tests - new company
Hi - A couple weeks ago someone posted a new company offering thyroid tests that have blood drawing clinics in London and is very reasonably priced. I have just had an unfortunate experience with Medichecks as the clinic I chose in London had no appointments for over a month. I am being issued a refund
Hi - A couple weeks ago someone posted a new company offering thyroid tests that have blood drawing clinics in London and is very reasonably priced. I have just had an unfortunate experience with Medichecks as the clinic I chose in London had no appointments for over a month. I am being issued a refund
Libuse
in
Thyroid UK
7 months ago
Warren Farr
Hi, my name is warren I was diagnosed in late November 2023 with Prostrate Cancer from a MRI I then had a PSMA CT Scan and the next day Robotic removal of my prostrate RRP. The Biopsy showed staging pT3b 30% ductal after a Gleason score of 5+4=9 My PSA after removal was 0.22 then 4 weeks later 0.38
Hi, my name is warren I was diagnosed in late November 2023 with Prostrate Cancer from a MRI I then had a PSMA CT Scan and the next day Robotic removal of my prostrate RRP. The Biopsy showed staging pT3b 30% ductal after a Gleason score of 5+4=9 My PSA after removal was 0.22 then 4 weeks later 0.38
Snoopy8125
in
Advanced Prostate Cancer
7 months ago
Malecare newsletter reports Finish study glucocorticoids (e.g. prednisone, prednisolone, dexamethasone) can lead to castrate resistance
“However, recent studies have shown that the glucocorticoid receptor also has an oncogenic, or cancer-promoting, effect in cancers like breast and prostate cancer. In prostate cancer, the glucocorticoid receptor can replace the activity of the androgen receptor, which is main oncogenic factor in this
“However, recent studies have shown that the glucocorticoid receptor also has an oncogenic, or cancer-promoting, effect in cancers like breast and prostate cancer. In prostate cancer, the glucocorticoid receptor can replace the activity of the androgen receptor, which is main oncogenic factor in this
Graham49
in
Advanced Prostate Cancer
5 months ago
Newly diagnosed with HCC
I am a 78 year old retired educator who has battled GIST CANCER for 20 years. To my surprise, An HCC tumor was found in my liver in between two GIST tumors. in my June 5 MRI. The GIST tumors were shrinking out of site thanks to be taking Gleevec, a targeted therapy drug. My surgeon could not safely resect
I am a 78 year old retired educator who has battled GIST CANCER for 20 years. To my surprise, An HCC tumor was found in my liver in between two GIST tumors. in my June 5 MRI. The GIST tumors were shrinking out of site thanks to be taking Gleevec, a targeted therapy drug. My surgeon could not safely resect
Dachshund45
in
Blue Faery Liver Cancer
3 months ago
A Secondary Primary Malignancy hit me
The doctors tell us that you don't die from CLL; you die with CLL. What they don't tell you very often is that even though it isn't the CLL that gets you, it could very well be a secondary primary malignancy caused by the CLL that does it. Bennevisplace wrote on this a few months ago; i.e. the fact
The doctors tell us that you don't die from CLL; you die with CLL. What they don't tell you very often is that even though it isn't the CLL that gets you, it could very well be a secondary primary malignancy caused by the CLL that does it. Bennevisplace wrote on this a few months ago; i.e. the fact
hhk50
in
CLL Support
3 months ago
Tomorrow is finally the day of my MRI after waiting 3 1/2 months since the ultrasound and CT scan couldn't be sure of a mass or not.
After having to postpone my original MRI appt last month due to the death of my mother, I am finally getting it done tomorrow. Those who haven't read my previous posts, a fibroid and possible ovarian mass were found on an incidental CT scan back in March where I was diagnosed with diverticulitis after
After having to postpone my original MRI appt last month due to the death of my mother, I am finally getting it done tomorrow. Those who haven't read my previous posts, a fibroid and possible ovarian mass were found on an incidental CT scan back in March where I was diagnosed with diverticulitis after
starrynight5626
in
My Ovacome
3 months ago
Testosterone Levels and Prostate Cancer Risk - 1
This plot shows the association of baseline testosterone levels with PCa aggressiveness. For example, if you have low aggressive PCA, your testosterone is likely to be Normal. But, if you have metastatic PCa, your testosterone is likely to be very Low. This shows that having normal testosterone
This plot shows the association of baseline testosterone levels with PCa aggressiveness. For example, if you have low aggressive PCA, your testosterone is likely to be Normal. But, if you have metastatic PCa, your testosterone is likely to be very Low. This shows that having normal testosterone
janebob99
in
Advanced Prostate Cancer
7 months ago
Testosterone levels and Prostate Cancer Risk - 1
This plot shows the association of baseline testosterone levels with PCa aggressiveness. For example, if you have low aggressive PCA, your testosterone is likely to be Normal. But, if you have metastatic PCa, your testosterone is likely to be very Low. This shows that having normal testosterone levels
This plot shows the association of baseline testosterone levels with PCa aggressiveness. For example, if you have low aggressive PCA, your testosterone is likely to be Normal. But, if you have metastatic PCa, your testosterone is likely to be very Low. This shows that having normal testosterone levels
janebob99
in
Prostate Cancer Network
7 months ago
Castrate levels of Testosterone
My husband's testosterone level is 3nmol/L (86.5 ng/100ml). In the past year, his levels have ranged between 2-8 nmol/L. He's on quarterly Zoladex. I understand that castrate levels are ideally < 20 ng/100ml. If I understand correctly, his testosterone should be much lower. Can anyone please shed
My husband's testosterone level is 3nmol/L (86.5 ng/100ml). In the past year, his levels have ranged between 2-8 nmol/L. He's on quarterly Zoladex. I understand that castrate levels are ideally < 20 ng/100ml. If I understand correctly, his testosterone should be much lower. Can anyone please shed
cancervictim
in
Advanced Prostate Cancer
7 months ago
Looking for advice for my newly diagnosed dad
Hello, I was wondering if you can offer some thoughts on my dad’s situation. He was diagnosed with prostate cancer in February after a week in hospital with urine retention. A Ct scan he had in hospital showed 2 small mets in pelvic area. He’s had a biopsy which showed Gleason 4 +5 and his PSA in hospital
Hello, I was wondering if you can offer some thoughts on my dad’s situation. He was diagnosed with prostate cancer in February after a week in hospital with urine retention. A Ct scan he had in hospital showed 2 small mets in pelvic area. He’s had a biopsy which showed Gleason 4 +5 and his PSA in hospital
Springsunshi
in
Advanced Prostate Cancer
5 months ago
Guided bacteria, 100% effective in preclinical trials
well, I am citing... "With a 100% remission rate and no meaningful side effects in all the subjects of the company's preclinical trials, this technology is conceived to address all solid tumors, representing 90% of cancer and 89% of deaths." Even 50% of that result in humans would be amazing! https
well, I am citing... "With a 100% remission rate and no meaningful side effects in all the subjects of the company's preclinical trials, this technology is conceived to address all solid tumors, representing 90% of cancer and 89% of deaths." Even 50% of that result in humans would be amazing! https
Maxone73
in
Advanced Prostate Cancer
3 months ago
Very promising: PIP Polyspecific Integrin-Binding Peptide, a novel and very flexible platform
Basically, they have developed a technology that can simultaneously bind to different "proteins" expressed by cancers. This means a wider specificity. One cancer mutation could express for example KRAS 12C and another KRAS 12D (just an example using terms and mutation I know!) and the chemo drug would
Basically, they have developed a technology that can simultaneously bind to different "proteins" expressed by cancers. This means a wider specificity. One cancer mutation could express for example KRAS 12C and another KRAS 12D (just an example using terms and mutation I know!) and the chemo drug would
Maxone73
in
Advanced Prostate Cancer
3 months ago
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