well, I am citing...
"With a 100% remission rate and no meaningful side effects in all the subjects of the company's preclinical trials, this technology is conceived to address all solid tumors, representing 90% of cancer and 89% of deaths."
Even 50% of that result in humans would be amazing!
Pretty amazing. Technology is directed at solid tumors. Would like to see actual data (published and reviewed) from a trial.
One more reason to use PEMF during Chemo. I was reading about that since couple of months but this trial validated it with trial. What Tall Allen calls pseudoscience is actually becoming cutting-edge science.
but it's not the magnetic field killing the cancer in this case, it's used only to guide and keep the bacteria in the right place while they deliver the payload
I'm sorry, but I can't take any organization with "Magnetodrones" seriously.
Well, nothing surprises me when it comes from scientists and their naming skills since I discovered the Sonic Hedgehog protein!
Maybe sonic bat therapy would float your boat? 🤷😉
The pitch seems interesting, but human trials won't start until 2025. The board for the company seems impressive - lots of ex-Presidents of large pharma and medical companies.
a note of cynicism here after reading that. So the tech is to inject the stuff into a tumor then hold it there with magnetic fields. The immediate problem I can see is with mets the solid tumors may he innumerable and in a range of sizes down to those not picked up yet. The chances magic tumor killing stuff can be injected into all of them and held in all of them? seems unlikely.
"They are injected directly into a tumor and can swim in tumors without using blood vessels or circulating in the bloodstream." I am not sure they could work with bone mets either, but it's still a very impressive delivery technology!
"A preclinical study has demonstrated that introducing the living Starpax Magnetodrones™ alone into a tumor, without transporting the drug, triggers the immune cells, and a substantial regression of the tumor was observed.
The Starpax treatment may cause a systemic immune response generating immune cells that could attack floating cancer cells in the rest of the patient’s body and remote metastases, without any Magnetodrones™ or anti-cancer drug circulating in the body."
From their website.
It's quite interesting to be honest, it seems to be designed to attack hypoxic cancer stem cells.
"Hypoxic zones in a tumor are areas where oxygen is virtually absent. Hypoxic zones are where stem cells are located; they are a primary driver of metastatic spread.
When the Magnetodrones™ pass by a hypoxic zone, they stop “swimming” and accumulate inside the hypoxic zone due to the level of oxygen within the hypoxic zone being the same as in their culture medium. They release a specific drug proven to work in hypoxic areas where stem cells are located.
For decades, several studies have demonstrated that chemotherapy, radiotherapy, or immunotherapy are barely effective in hypoxic zones."
Obviously worth keeping an eye on however regarding the 100% effective trials - what tumors? what types of cancer? was it stage 4? immunotherapy has been trying to activate the bodies immune system against prostate cancer, without much luck for years now. It isnt too clear to me why delivering a substance into the middle of a tumor changes that equation but maybe it does.
From their website I think that the first going into human trials phase 1 will be: pancreas, prostate, head and neck, colorectal, vulvar and breast. Using SN38 as chemotherapy.
Then they have another combination (with taxanes) that is still in preclinical for prostate, breast, head and neck and one that is not yet specified.
From what I have read, apart from their technology, they will have to ask permission to FDA to test every combination of their technology + chemotherapy.
The test was on HCT116, colorectal cancer.
here you go, it's easier with a picture!
I'm going to go through my old man shit stuff I've collected over many many years and see if I can find those tiny Scottie dog magnets that I use to play with before I discovered girls. Those magnets used to come in a pair (all white and all black). Like any of you actually give a shit about my magnets and the history. C'est la vie...
Good Luck, Good Health and Good Humor.
j-o-h-n
I care...
Now that makes two of us..........Thanks
Good Luck, Good Heath and Good Humor.
j-o-h-n
They are not releasing info of the preclinical trials which would be standard procedure, cancer and drug types. Anyway, we just have to wait and see. They have raised 24 million USD, the investors must have mor info.
Everyone here knows they can put a needle anywhere they choose, since we've been biosied. Why they don't want to use the same path to get treatment to the tumor baffles me. How many of the agents they inject into the arm or butt might be effective if they put them directly into the tumor is an interesting question that I'd like to have answered. I'll be first in line for almost any such treatment.
John
Reasonable point. Focal therapies try to do just that as well.
Thinking About “Median Survival” in Clinical Trials. 
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New technology that pinpoints prostate cancer will transform care
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'Substandard' Control Arms in Clinical Trials– Practice found common in prostate cancer studies
