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Very promising: PIP Polyspecific Integrin-Binding Peptide, a novel and very flexible platform
Basically, they have developed a technology that can simultaneously bind to different "proteins" expressed by cancers. This means a wider specificity. One cancer mutation could express for example KRAS 12C and another KRAS 12D (just an example using terms and mutation I know!) and the chemo drug would
Basically, they have developed a technology that can simultaneously bind to different "proteins" expressed by cancers. This means a wider specificity. One cancer mutation could express for example KRAS 12C and another KRAS 12D (just an example using terms and mutation I know!) and the chemo drug would
Maxone73
in
Advanced Prostate Cancer
3 months ago
Consider the options?
Post total hysterectomy, etc., one cycle of carboplatin (couldn't tolerate paclitaxel) and now on Avastin i/v and Olaparib. CA 9, which is fantastic. Side effects are just destroying me. I am 80, the Olaparib goes through to mid June 2026 and the Avastin finishes at the end of this year. Oncologist
Post total hysterectomy, etc., one cycle of carboplatin (couldn't tolerate paclitaxel) and now on Avastin i/v and Olaparib. CA 9, which is fantastic. Side effects are just destroying me. I am 80, the Olaparib goes through to mid June 2026 and the Avastin finishes at the end of this year. Oncologist
Pawpaw22
in
My Ovacome
3 months ago
slight CEA Elevation
hi everyone- my father has MBC and is currently on Lynparza / Olaparib to target the BRCA2 gene mutation. He has been on it for 9 months and had a scan that showed complete control over his breast cancer on May 21st (not too long ago at all). The only thing that “lit up” on the scan was his Prostate
hi everyone- my father has MBC and is currently on Lynparza / Olaparib to target the BRCA2 gene mutation. He has been on it for 9 months and had a scan that showed complete control over his breast cancer on May 21st (not too long ago at all). The only thing that “lit up” on the scan was his Prostate
Jenniferp2122
in
SHARE Metastatic Breast Cancer
3 months ago
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Be careful: Pluvicto controversy, dammit!
not saying that it does not work, in fact for some patients it is simply fantastic, but still...they have damaged their reputation with patients https://www.nature.com/articles/s44276-024-00065-7 The PSMAfore and VISION trials for Lutetium-177 PSMA-617 in prostate cancer exhibit design flaws that bias
not saying that it does not work, in fact for some patients it is simply fantastic, but still...they have damaged their reputation with patients https://www.nature.com/articles/s44276-024-00065-7 The PSMAfore and VISION trials for Lutetium-177 PSMA-617 in prostate cancer exhibit design flaws that bias
Maxone73
in
Advanced Prostate Cancer
3 months ago
thinning hair and skin problem with IBS
I have had IBS(D) for more than 40 years which has gradually got worse over the years , more pain all over my abdomen radiating under right and left ribs ! I have had cat scans ,colonoscopies and blood tests over the years all normal ; I notice in the last few years my hair is getting thinner and
I have had IBS(D) for more than 40 years which has gradually got worse over the years , more pain all over my abdomen radiating under right and left ribs ! I have had cat scans ,colonoscopies and blood tests over the years all normal ; I notice in the last few years my hair is getting thinner and
Mascot68
in
IBS Network
3 months ago
Advise for a new diagnosis
Dear community, I wanted to post a message to this forum to ask for advice for my mum who has recently been diagnosed with metastatic breast cancer. Her biopsy is still being tested to determine the exact subtype. Doctors could not see anything un the breast and took a biopsy was taken from one of
Dear community, I wanted to post a message to this forum to ask for advice for my mum who has recently been diagnosed with metastatic breast cancer. Her biopsy is still being tested to determine the exact subtype. Doctors could not see anything un the breast and took a biopsy was taken from one of
Blossom751
in
SHARE Metastatic Breast Cancer
3 months ago
The party is over …
Hi Everyone, Well, that dripping tap must have got me, finally!! No symptoms but a routine Rheumy appt preceded by the usual blood tests revealed that my CRP is over 100 😱 and my ESR is 80 something. But I feel no pain, except for the usual little niggles that I thought came with being nearly 70.
Hi Everyone, Well, that dripping tap must have got me, finally!! No symptoms but a routine Rheumy appt preceded by the usual blood tests revealed that my CRP is over 100 😱 and my ESR is 80 something. But I feel no pain, except for the usual little niggles that I thought came with being nearly 70.
LemonZest11
in
PMRGCAuk
3 months ago
Finasteride: "Miracle drug" regrows hair, heals prostate, and also boosts heart health ByEric Ralls Earth.com
I am now thinking to add Finasteride to Bicalutamide plus degarelix injections. Would/could it help me if on the psma pet scan my only visible cancer is in my prostate? I had radiation therapy to my prostate but my prostate cancer is back and looks like that the radiation therapy failed and the most
I am now thinking to add Finasteride to Bicalutamide plus degarelix injections. Would/could it help me if on the psma pet scan my only visible cancer is in my prostate? I had radiation therapy to my prostate but my prostate cancer is back and looks like that the radiation therapy failed and the most
Seasid
in
Advanced Prostate Cancer
7 months ago
MRI report shows enhancing bone lesion is noted involving the left sphenoid bone.
That’s from an MRI taken six weeks after 10 sessions of IMRT were completed for a surgically inoperable metastasis in my skull. Apparently this means the contrast agent shows increased blood flow or activity in the tumor. Does that sound normal to still have increased blood flow or activity six weeks
That’s from an MRI taken six weeks after 10 sessions of IMRT were completed for a surgically inoperable metastasis in my skull. Apparently this means the contrast agent shows increased blood flow or activity in the tumor. Does that sound normal to still have increased blood flow or activity six weeks
Gl448
in
Advanced Prostate Cancer
3 months ago
Hi I'm Tawnie 🤗
Hey everybody happy Sunday 😇I have a biopsy the 26th and I'm deadly afraid doctor said there was skin cancer it's everywhere the lesions are getting worse by the day... The pain of the lesions is getting very bad can't even touch them I was just wondering how are you all handling or do you have pain
Hey everybody happy Sunday 😇I have a biopsy the 26th and I'm deadly afraid doctor said there was skin cancer it's everywhere the lesions are getting worse by the day... The pain of the lesions is getting very bad can't even touch them I was just wondering how are you all handling or do you have pain
Tawnie123
in
MY SKIN
3 months ago
Stop Ibrance?
My HB and Platelets have been bad for a while. Mainly because I haven' eaten anything. I am now eating again and feel much better (I had other reasons), but she has ordered me back for new blood tests and wants me to change to Xeloda. I want a chance to get my appetite back up and eating normally before
My HB and Platelets have been bad for a while. Mainly because I haven' eaten anything. I am now eating again and feel much better (I had other reasons), but she has ordered me back for new blood tests and wants me to change to Xeloda. I want a chance to get my appetite back up and eating normally before
SwedishSissi
in
SHARE Metastatic Breast Cancer
3 months ago
upcoming PET scan
so, here’s where we are… My Joe has been experiencing increasing pain in his left hip and thigh. Today he said the thigh is numb. PET scan scheduled this coming Tuesday. He thinks it’s a hairline fracture. Is it wrong of me to hope he’s right, vs his cancer having landed there? He’s 4 months post-Pluvicto
so, here’s where we are… My Joe has been experiencing increasing pain in his left hip and thigh. Today he said the thigh is numb. PET scan scheduled this coming Tuesday. He thinks it’s a hairline fracture. Is it wrong of me to hope he’s right, vs his cancer having landed there? He’s 4 months post-Pluvicto
Cateydid
in
Advanced Prostate Cancer
3 months ago
Silly Questions??
1) Why do some advanced prostate cancer patients get offered "vacations", from ADT and others don't? 2) Why do some advanced prostate cancer patients have NO Chemo, and go directly to ADT + Abiraterone+Prednisone, while others begin treatment with chemo and radiation? What are the deciding criteria
1) Why do some advanced prostate cancer patients get offered "vacations", from ADT and others don't? 2) Why do some advanced prostate cancer patients have NO Chemo, and go directly to ADT + Abiraterone+Prednisone, while others begin treatment with chemo and radiation? What are the deciding criteria
TommyCarz2
in
Advanced Prostate Cancer
7 months ago
sweet sugar taste after 3rd docetaxel infusion
anyone ever have a really sweet sugary taste after docetaxel. after the first 2 my taste went back to normal after about 7 days but the only problem i had was with spicy foods. after my 3rd round i have a super sweet sugary taste all the time for 16 days now. i have a hard time eating because almost
anyone ever have a really sweet sugary taste after docetaxel. after the first 2 my taste went back to normal after about 7 days but the only problem i had was with spicy foods. after my 3rd round i have a super sweet sugary taste all the time for 16 days now. i have a hard time eating because almost
casperrose
in
Advanced Prostate Cancer
3 months ago
Xtandi--Eligibility
Hello, I have been taking Xtandi since June 2022, It has taken my PSA down to <.01 (less than) and so far has kept it there. Which I am very grateful! I am self pay and not old enough to have Medicare (just turned 64). I have recieved the Xtandi thru Astellas pharmacy in Texas. I have always qualified
Hello, I have been taking Xtandi since June 2022, It has taken my PSA down to <.01 (less than) and so far has kept it there. Which I am very grateful! I am self pay and not old enough to have Medicare (just turned 64). I have recieved the Xtandi thru Astellas pharmacy in Texas. I have always qualified
JD-guy
in
Advanced Prostate Cancer
7 months ago
Minor psa increase again
Just over 12 months since adt finished. All clear at <0.01 2 months ago when it started to rise to 0.03 then 4 weeks later 0.05 now 0.07. Have Dr's app in 3 weeks which will probably be a referral back to oncologist. Do we need to wait until 2.0 then a PET scan or can I be proactive now? My adt was
Just over 12 months since adt finished. All clear at <0.01 2 months ago when it started to rise to 0.03 then 4 weeks later 0.05 now 0.07. Have Dr's app in 3 weeks which will probably be a referral back to oncologist. Do we need to wait until 2.0 then a PET scan or can I be proactive now? My adt was
Runner1957
in
Prostate Cancer Network
3 months ago
Ready, Set, GO!! LOL
Hi all of my beautiful warrior friends!!! I would like to know what you all have had as far as treatment. I am really most interested in people like me, who have had NO mutations. I am ER+, HER2 LOW I am about to start on Enhertu, but my doctor is hedging to the possibility that I am running out
Hi all of my beautiful warrior friends!!! I would like to know what you all have had as far as treatment. I am really most interested in people like me, who have had NO mutations. I am ER+, HER2 LOW I am about to start on Enhertu, but my doctor is hedging to the possibility that I am running out
CTGirl1962
in
SHARE Metastatic Breast Cancer
3 months ago
Enhertu
Good morning. Has anyone taken Enhertu for breast cancer? What are your pros/cons? Little back story: dx stage 4 metastatic breast cancer, ER/PR +, HERS2 -, but I am considered HERS2 low w/ a count of 1, in April 2022, I was 44 at the time. Left breast, lymph node in left armpit, multiple spots in my
Good morning. Has anyone taken Enhertu for breast cancer? What are your pros/cons? Little back story: dx stage 4 metastatic breast cancer, ER/PR +, HERS2 -, but I am considered HERS2 low w/ a count of 1, in April 2022, I was 44 at the time. Left breast, lymph node in left armpit, multiple spots in my
Felicia1228
in
SHARE Metastatic Breast Cancer
3 months ago
Autovaccination seems a hot topic lately: Mt. Sinai autovaccination technique to turn cold prostate cancer hot (Phase 1)
ok, I am exposing myself to j-o-h-n in more than one way with that title... This is for regional leagues (locally advanced PCa), while we are the NFL of prostate cancer here, but the fact that a cold cancer was turned hot is very promising as it has always been the main limit of immuno therapies applied
ok, I am exposing myself to j-o-h-n in more than one way with that title... This is for regional leagues (locally advanced PCa), while we are the NFL of prostate cancer here, but the fact that a cold cancer was turned hot is very promising as it has always been the main limit of immuno therapies applied
Maxone73
in
Advanced Prostate Cancer
5 months ago
MRI scan results
I have had back issues for many years but in March this flare up seemed different. I finally went private for a consultation which quickly lead to an MRI scan last week. The consultant called me within 5 days, this set off alarm bells as usually takes 2 weeks plus, to say I have a growth which he would
I have had back issues for many years but in March this flare up seemed different. I finally went private for a consultation which quickly lead to an MRI scan last week. The consultant called me within 5 days, this set off alarm bells as usually takes 2 weeks plus, to say I have a growth which he would
NickyRobinson
in
MPN Voice
3 months ago
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