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Narirutin found in lemons, oranges, passion fruit, bergamot and grapefruit may be chemopreventive agent for hormone-resistant PC
Narirutin. A flavonoid found in citrus fruits modulates cell cycle phases and inhibits the proliferation of hormone-refractory prostate cancer cells by targeting hyaluronidase Author links open overlay panelShilpi Singh a b, Akhilesh Kumar Maurya c, Abha Meena a b, Nidhi Mishra c, Suaib Luqman a b
Narirutin. A flavonoid found in citrus fruits modulates cell cycle phases and inhibits the proliferation of hormone-refractory prostate cancer cells by targeting hyaluronidase Author links open overlay panelShilpi Singh a b, Akhilesh Kumar Maurya c, Abha Meena a b, Nidhi Mishra c, Suaib Luqman a b
Graham49
in
Advanced Prostate Cancer
10 months ago
Unrelated to Parkinson's
Prior to 1980 about the only relativly common form of thiamin was thiamin hcl and then most vitamins and enritched food products changed to thiamin mononitrate. While thiamin HCL is a wonderful form of thiamin for 99.99 % of the population for some reason I can't take it. When I take thiamin HCL in
Prior to 1980 about the only relativly common form of thiamin was thiamin hcl and then most vitamins and enritched food products changed to thiamin mononitrate. While thiamin HCL is a wonderful form of thiamin for 99.99 % of the population for some reason I can't take it. When I take thiamin HCL in
Woodyx2
in
Cure Parkinson's
10 months ago
tramadol
I was on tramadol for at least 10 years----100 mg. then my doc took me off because a neurologist put me on Clonazepam for REM/SBD (rapid eye movement sleep behavior disorder.) But I was also getting cervical and lumbar rhizotomies...and still do every 12-14 months or so. I am now working with the VA
I was on tramadol for at least 10 years----100 mg. then my doc took me off because a neurologist put me on Clonazepam for REM/SBD (rapid eye movement sleep behavior disorder.) But I was also getting cervical and lumbar rhizotomies...and still do every 12-14 months or so. I am now working with the VA
Shadowperson
in
Pain Concern
10 months ago
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LDH high
Looking back, my specialist tested my LDH at diagnosis and it was in fact elevated. He told me that it’s very common for MPN’s to cause elevated LDH levels and said with treatment we can correct them.. is that true? I was worried for a second about any organ or tissue damage, but he reassured and said
Looking back, my specialist tested my LDH at diagnosis and it was in fact elevated. He told me that it’s very common for MPN’s to cause elevated LDH levels and said with treatment we can correct them.. is that true? I was worried for a second about any organ or tissue damage, but he reassured and said
JAKboy
in
MPN Voice
10 months ago
TSH increased but no medication change
Hi, My recent blood tests showed my TSH has increased from 1.12 to 2.4 and I haven’t changed anything. Is there a reason this would happen or does it just fluctuate? I have been eating a lot of cruciferous everyday. Would that have an impact? My FT4 has remained pretty constant.
Hi, My recent blood tests showed my TSH has increased from 1.12 to 2.4 and I haven’t changed anything. Is there a reason this would happen or does it just fluctuate? I have been eating a lot of cruciferous everyday. Would that have an impact? My FT4 has remained pretty constant.
Emj001
in
Thyroid UK
10 months ago
Selegiline run out
I was told recently by my pharmacist they couldn't get any Selegiline and to ask my GP for an alternative. I still have 60 10mg tablets left and will have to inform GP soon. (I'm still waiting on my first appointment with neurologist in my new location, been waiting months as unfortunately I had to
I was told recently by my pharmacist they couldn't get any Selegiline and to ask my GP for an alternative. I still have 60 10mg tablets left and will have to inform GP soon. (I'm still waiting on my first appointment with neurologist in my new location, been waiting months as unfortunately I had to
Ardbeg28
in
Cure Parkinson's
11 months ago
**TW** TFMR Trisomy 18 help needed
Hi,Not the update I wanted to post. A very detailed anatomy scan today showed positive signs for Trisomy 18. The consultant said he was sorry and gave me my options. I've chosed to terminate the pregnancy for medical reasons as this abnormality isn't compatible with life. I'm absolutely heartbroken
Hi,Not the update I wanted to post. A very detailed anatomy scan today showed positive signs for Trisomy 18. The consultant said he was sorry and gave me my options. I've chosed to terminate the pregnancy for medical reasons as this abnormality isn't compatible with life. I'm absolutely heartbroken
Molliemoo85
in
Fertility Network UK
11 months ago
20 July 2023 Every little bit helps
G'day my ms family. How are YOU today? No, how are YOU really? I know I do not tell my wife every little thing and I know it works the same for her. There is a little apprehension always in the back of your head deep down where people do not see. This is normal. Do not panic. We all
G'day my ms family. How are YOU today? No, how are YOU really? I know I do not tell my wife every little thing and I know it works the same for her. There is a little apprehension always in the back of your head deep down where people do not see. This is normal. Do not panic. We all
RoyceNewton
in
My MSAA Community
11 months ago
Advice desperately needed please
Has anybody who can only take Zentiva hydroxychloroquine been offered IPCA Hydroxychloroquine? Has it same make up as Quinoric or bristol laborotories? If you have did you tolerate it ok please. As yet again cannot get Zentiva!! I find it so frustrating, that I am now in tears over it, any info very
Has anybody who can only take Zentiva hydroxychloroquine been offered IPCA Hydroxychloroquine? Has it same make up as Quinoric or bristol laborotories? If you have did you tolerate it ok please. As yet again cannot get Zentiva!! I find it so frustrating, that I am now in tears over it, any info very
Poshcards
in
LUpus Patients Understanding and Support
11 months ago
Looking for guidance on RLS and Parkinson's Management
Good Morning, Read this forum regularly... thank you for sharing ... Looking to learn more about RLS and Parkinson's, especially from persons with these two conditions particularly their medication management. My husband has both conditions, RLS since mid 2000s, Parkinson's since 2018. And we are
Good Morning, Read this forum regularly... thank you for sharing ... Looking to learn more about RLS and Parkinson's, especially from persons with these two conditions particularly their medication management. My husband has both conditions, RLS since mid 2000s, Parkinson's since 2018. And we are
gardening57
in
Restless Legs Syndrome
11 months ago
Good resources regarding vagal AFIB?
Does anyone have any good resources (articles, YouTube videos) directed to vagally-mediated AFIB (the type that occurs after a large meal or while sleeping)? I believe my AFIB was triggered by endurance athletics (I used to do long bike rides and probably overdid it and stressed my body too much).
Does anyone have any good resources (articles, YouTube videos) directed to vagally-mediated AFIB (the type that occurs after a large meal or while sleeping)? I believe my AFIB was triggered by endurance athletics (I used to do long bike rides and probably overdid it and stressed my body too much).
dw98611
in
AF Association
11 months ago
*Long Read Warning* How do you know if you’re getting better mentally?
Just need to vent, if you read this and commented thankyou, it helps getting another perspective on the situation. Male, 20 Parents went through a divorce in 2022 and it was ugly to say the least. (Mom was an alcoholic, dad was a cop and emotionally distant due to his Mexican culture and upbringing
Just need to vent, if you read this and commented thankyou, it helps getting another perspective on the situation. Male, 20 Parents went through a divorce in 2022 and it was ugly to say the least. (Mom was an alcoholic, dad was a cop and emotionally distant due to his Mexican culture and upbringing
Bear2024
in
Above & Beyond
4 days ago
Need Help Sleeping? THE MOST BORING VIDEO EVER MADE (Microsoft Word tutorial, 1989)
A YouTube video dubbed the 'most boring video of all time' has racked up more than three million views from a legion of fans hailing it as the ultimate sleep aid. https://www.dailymail.co.uk/news/article-13388461/boring-video-microsoft-word-randy-smith-youtube.html
THE MOST BORING VIDEO EVER MADE
A YouTube video dubbed the 'most boring video of all time' has racked up more than three million views from a legion of fans hailing it as the ultimate sleep aid. https://www.dailymail.co.uk/news/article-13388461/boring-video-microsoft-word-randy-smith-youtube.html
THE MOST BORING VIDEO EVER MADE
Bolt_Upright
in
Cure Parkinson's
27 days ago
Daridexorant / quvuviq and RLS
Just wondering if anyone else has experience of this sleep aid and RLS? I have bought (not available in my region on NHS yet) a month’s supply of 50mg tablets and ….. I am sleeping normally!!!! It is a new drug to the UK but tried and tested in USA I believe? Apparently minimal side effects. I have
Just wondering if anyone else has experience of this sleep aid and RLS? I have bought (not available in my region on NHS yet) a month’s supply of 50mg tablets and ….. I am sleeping normally!!!! It is a new drug to the UK but tried and tested in USA I believe? Apparently minimal side effects. I have
Lacey_
in
Restless Legs Syndrome
1 month ago
Fatigue
Since being diagnosed with an inflammatory disorder three years ago I have suffered with various symptoms most of which are now well controlled and stable. The severe pain in my joints and other parts of my body and the excruciatingly painful headaches thankfully seem to be kept at bay by medication
Since being diagnosed with an inflammatory disorder three years ago I have suffered with various symptoms most of which are now well controlled and stable. The severe pain in my joints and other parts of my body and the excruciatingly painful headaches thankfully seem to be kept at bay by medication
Hightower62
in
NRAS
11 months ago
NOCTURIA POST RT 5-6 x Night, Orgovyx Finished TX one month ago -still having SE's.
Finished 20 TX IMRT & 4 months Orgovyzx I finished RT 3 months ago finished -4 mos of Orgovyx one month ago. RT-Now having Nocturia -getting up 5 x a night -taking 2 flomax a day -need tips how to reduce number of x going? a. how long does it generally take for the radiation inflamed uretha
Finished 20 TX IMRT & 4 months Orgovyzx I finished RT 3 months ago finished -4 mos of Orgovyx one month ago. RT-Now having Nocturia -getting up 5 x a night -taking 2 flomax a day -need tips how to reduce number of x going? a. how long does it generally take for the radiation inflamed uretha
JWS13
in
Advanced Prostate Cancer
11 months ago
sleep aid
just sharing a link that is a new product helpful for sleep. It was recommended by a very well know integrative doctor in California. I am not recommending it for restless legs, but my sister and her husband say it helps with sleep. https://lifewave.com
just sharing a link that is a new product helpful for sleep. It was recommended by a very well know integrative doctor in California. I am not recommending it for restless legs, but my sister and her husband say it helps with sleep. https://lifewave.com
RCHD
in
Restless Legs Syndrome
2 months ago
fatigue
Hello I’m ET jak2 positive and suffer from extreme fatigue. I am currently off work and eager to return, I have been reading an article about MPN and the use of antidepressants to combat the fatigue Some antidepressants may help combat fatigue. Additionally, several small trials have found an increase
Hello I’m ET jak2 positive and suffer from extreme fatigue. I am currently off work and eager to return, I have been reading an article about MPN and the use of antidepressants to combat the fatigue Some antidepressants may help combat fatigue. Additionally, several small trials have found an increase
YBSx
in
MPN Voice
11 months ago
PERIODIC LIMB MOVEMENT DISORDER
I have not shared for a while. I would like to report that I have been taking the iron supplement every other day with orange juice. Also am taking 300 Gabapentin. I did a sleep study last year and it showed that the PLMD is not disturbing my sleep as it is now at a moderate amount. The sleep study
I have not shared for a while. I would like to report that I have been taking the iron supplement every other day with orange juice. Also am taking 300 Gabapentin. I did a sleep study last year and it showed that the PLMD is not disturbing my sleep as it is now at a moderate amount. The sleep study
Maximus01
in
Restless Legs Syndrome
11 months ago
Members' Day talk on steroid side-effects in PMR and GCA: the lived experience day to day
Our AGM and Members' Day is to be held on 9th September, 11am-1pm (BST). If you're a member of the charity, you should have received an email or letter with details of how to register. We are thrilled to be welcoming four speakers to the event: Dr Lorraine Watson PhD RD FHEA, NIHR SPCR Post-Doctoral
Our AGM and Members' Day is to be held on 9th September, 11am-1pm (BST). If you're a member of the charity, you should have received an email or letter with details of how to register. We are thrilled to be welcoming four speakers to the event: Dr Lorraine Watson PhD RD FHEA, NIHR SPCR Post-Doctoral
Fran_Benson
Partner
in
PMRGCAuk
11 months ago
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