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Enzalutamide & 5-year survival in mHSPC.
More from ASCO 2023 [1] [2]. "Patients in the ENZAMET trial (n = 1125) were randomized 1:1 to arm A, the control arm consisting of TS plus a standard non-steroidal antiandrogen ([NSAA] bicalutamide, nilutamide, or flutamide), or enzalutamide at 160 mg per day plus TS in arm B. " "The 5-year OS rates
More from ASCO 2023 [1] [2]. "Patients in the ENZAMET trial (n = 1125) were randomized 1:1 to arm A, the control arm consisting of TS plus a standard non-steroidal antiandrogen ([NSAA] bicalutamide, nilutamide, or flutamide), or enzalutamide at 160 mg per day plus TS in arm B. " "The 5-year OS rates
pca2004
in
Fight Prostate Cancer
11 months ago
Darolutamide & time to treatment discontinuation in nmCRPC
Further to the recent Apalutamide thred, we now have [1]: "A real-world analysis of the androgen receptor inhibitors (ARIs) darolutamide (Nubeqa), enzalutamide (Xtandi), and apalutamide (Erleada) found that darolutamide had a longer time to treatment discontinuation and longer time to progression to
Further to the recent Apalutamide thred, we now have [1]: "A real-world analysis of the androgen receptor inhibitors (ARIs) darolutamide (Nubeqa), enzalutamide (Xtandi), and apalutamide (Erleada) found that darolutamide had a longer time to treatment discontinuation and longer time to progression to
pca2004
in
Fight Prostate Cancer
11 months ago
Mouth ulcers
Hi everyone now on my fourth week of HU and another side effect.Any top tips for mouth ulcers would be appreciated.
Hi everyone now on my fourth week of HU and another side effect.Any top tips for mouth ulcers would be appreciated.
Spanelmad
in
MPN Voice
6 months ago
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Zoladex and HRT
I was diagnosed with endo in 2021, it was removed from my abdominal wall but my pain never fully left. Just 4 months later my symptoms returned and the pain was as bad as it was pre-op. Here I am, 19 months later in significant daily pain. I am signed off sick from work for the 3rd week, and it seems
I was diagnosed with endo in 2021, it was removed from my abdominal wall but my pain never fully left. Just 4 months later my symptoms returned and the pain was as bad as it was pre-op. Here I am, 19 months later in significant daily pain. I am signed off sick from work for the 3rd week, and it seems
Ccn2018
in
Endometriosis UK
11 months ago
Only Right side back pain after Fet
Hi all Ladies.Dies anyone felt the same as Iam🥲😢..i have severe back pain started last friday..a sharp back pain and and 2 days now. It hurt so much. Does this cause by stimulation and progesteron, is it ok to drink pain reliever. Im going also to call my clinic i necer ezperience this before, i felt
Hi all Ladies.Dies anyone felt the same as Iam🥲😢..i have severe back pain started last friday..a sharp back pain and and 2 days now. It hurt so much. Does this cause by stimulation and progesteron, is it ok to drink pain reliever. Im going also to call my clinic i necer ezperience this before, i felt
PrayingforMyBaby
in
Fertility Network UK
11 months ago
Enlarged Prostate Medication
Good afternoon. I’ve been recently diagnosed with enlarged prostate. My general health is not good as I had a Triple Bypass and Mitral Valve Repair and also, last year was diagnosed with Heart Failure. I’ve also got Severe Spinal Stenosis which has returned following a Failed Laminectomy Spine Operation
Good afternoon. I’ve been recently diagnosed with enlarged prostate. My general health is not good as I had a Triple Bypass and Mitral Valve Repair and also, last year was diagnosed with Heart Failure. I’ve also got Severe Spinal Stenosis which has returned following a Failed Laminectomy Spine Operation
Davewm
in
Men's Health Forum
11 months ago
Nerve compression after surgery for Cauda Equina
Ho- just wondered if anyone had been through a similar thing. A relative had surgery for Cauda Equina which failed. She had had a new nerve compression- due to pressure from centralised disc - but she has been refused surgery despite the excruciating pain. She has tried several neuropathic painkillers
Ho- just wondered if anyone had been through a similar thing. A relative had surgery for Cauda Equina which failed. She had had a new nerve compression- due to pressure from centralised disc - but she has been refused surgery despite the excruciating pain. She has tried several neuropathic painkillers
Mymysonlyone
in
Pain Concern
11 months ago
dental treatment, MTX , surgery and Co-vid booster all landing at the same time.
having a bit of a meltdown with this one, on 29th of this month I am having some planned renal surgery that I am paying to have done privately , the problem is this coming Friday 16th I am having dental work done ( it can’t wait so much pain) the night before is my last MTX before my op , and
having a bit of a meltdown with this one, on 29th of this month I am having some planned renal surgery that I am paying to have done privately , the problem is this coming Friday 16th I am having dental work done ( it can’t wait so much pain) the night before is my last MTX before my op , and
Gaz227
in
PMRGCAuk
11 months ago
ARRRGH !
Hi all, I live in Tasmania, Australia and do not have private health cover. I am 60 years old and have had rls since I was 21, that I know of. I have also been on antidepressants since 1980... I realky believe that they have caused the rls as no one in my family had it. Anyway, it became absolutely
Hi all, I live in Tasmania, Australia and do not have private health cover. I am 60 years old and have had rls since I was 21, that I know of. I have also been on antidepressants since 1980... I realky believe that they have caused the rls as no one in my family had it. Anyway, it became absolutely
Oscarcat63
in
Restless Legs Syndrome
11 months ago
Flaring up after Booster
Good morning all,I hope everyone is well as can be given their conditions. I read everyone's messages but rarely post. I had my fourth Covid vaccination yesterday morning. It should be my fifth but I didn't take the previous one. By late afternoon/evening, my shoulder was hurting and my hand and some
Good morning all,I hope everyone is well as can be given their conditions. I read everyone's messages but rarely post. I had my fourth Covid vaccination yesterday morning. It should be my fifth but I didn't take the previous one. By late afternoon/evening, my shoulder was hurting and my hand and some
Choccy23
in
NRAS
11 months ago
Pain that effects my life
Last 2 days had pain right side wrist leg and shoulder . Previously to this for years I had back ache and shoulder . I know think it could be possibly fibromeliga and will keep going back with a pain log . I went today but the doctor said I come to early and implying I am wasting there time . I did
Last 2 days had pain right side wrist leg and shoulder . Previously to this for years I had back ache and shoulder . I know think it could be possibly fibromeliga and will keep going back with a pain log . I went today but the doctor said I come to early and implying I am wasting there time . I did
Amanda556
in
Borders Pain Management
11 months ago
Hi Penny
I was on pred for 3 years for p m a.I reduced very slowly but it was extremely difficult once I hit 5mgms I then reduced by half a mgm every 2 months.At each reduction I experienced break through pain .When I finally stopped I was in severe pain but I persevered with the help of pain killers heat bags
I was on pred for 3 years for p m a.I reduced very slowly but it was extremely difficult once I hit 5mgms I then reduced by half a mgm every 2 months.At each reduction I experienced break through pain .When I finally stopped I was in severe pain but I persevered with the help of pain killers heat bags
Whist
in
NRAS
11 months ago
ibs-d and facing surgery
I’m having a knee replacement on Wednesday and worried about my ibs-d as bad at the mo. I’m taking loperamide but worried that if I take too many with the combination of strong painkillers I’ll end up constipated. Also concerned that as im having an epidural I wont be able to feel if I need to go😩
I’m having a knee replacement on Wednesday and worried about my ibs-d as bad at the mo. I’m taking loperamide but worried that if I take too many with the combination of strong painkillers I’ll end up constipated. Also concerned that as im having an epidural I wont be able to feel if I need to go😩
BasilG
in
IBS Network
11 months ago
Is codeine ok with prednisolone.
Foolishly went mad digging garden couple of weeks ago and upset my back....past slipped disc. Seeing pysio and doing all the right things and keeping pain killers to a minimum as even the paracetamol make me feel strange, light headed and upset digestive system. I am on omeprazole. Would codeine be a
Foolishly went mad digging garden couple of weeks ago and upset my back....past slipped disc. Seeing pysio and doing all the right things and keeping pain killers to a minimum as even the paracetamol make me feel strange, light headed and upset digestive system. I am on omeprazole. Would codeine be a
Ebiker
in
PMRGCAuk
11 months ago
More surgery....
So I finally got to see the endometriosis specialist again after screaming and shouting yet again, they told me they will finally take out my overies away and put me on prostap injections up until this surgery I really hope it helps, this is my last resort it's been years of pain pills injections and
So I finally got to see the endometriosis specialist again after screaming and shouting yet again, they told me they will finally take out my overies away and put me on prostap injections up until this surgery I really hope it helps, this is my last resort it's been years of pain pills injections and
Bubblepoppy
in
Endometriosis UK
11 months ago
Bit of a Vent
(Warning: I mention infertility a bit) Hi everyone, My suspected endometriosis has been getting worse and worse, especially after I’ve been put on the implant. I had to go to A&E for the doctor to tell me he didn’t even think morphine would help with my pain… I’ve had to take so many sick days from
(Warning: I mention infertility a bit) Hi everyone, My suspected endometriosis has been getting worse and worse, especially after I’ve been put on the implant. I had to go to A&E for the doctor to tell me he didn’t even think morphine would help with my pain… I’ve had to take so many sick days from
VioletCoffee
in
Endometriosis UK
11 months ago
Aplautamide, enzalutamide: low dose opinions
Hi Officially mcrpc. Can't get darolutamide so faced with choice of zytiga, xtandi or aplautamide in the coming weeks. Faced with the first two I would have opted for xtandi and hopefully worked towards taking two tablets. Maybe one but have seen a few progress at one and wonder if two would be an
Hi Officially mcrpc. Can't get darolutamide so faced with choice of zytiga, xtandi or aplautamide in the coming weeks. Faced with the first two I would have opted for xtandi and hopefully worked towards taking two tablets. Maybe one but have seen a few progress at one and wonder if two would be an
Rickytarr
in
Fight Prostate Cancer
11 months ago
Aging: Papers on diet, exercise, and caloric restriction effects on microbiome and epigenome
The following two articles were included in post by a member over at the HU CLLSupport site. (Thanks, Kwenda.) Both are review papers that look at the effects of diet and exercise on health outcomes. The second paper is much more technical in nature and is from researchers in Portugal. I'm including
The following two articles were included in post by a member over at the HU CLLSupport site. (Thanks, Kwenda.) Both are review papers that look at the effects of diet and exercise on health outcomes. The second paper is much more technical in nature and is from researchers in Portugal. I'm including
cujoe
in
Fight Prostate Cancer
11 months ago
Nerve pain, constant over 3 weeks
I believe I have posted my history with regard to this recent episode of severe pain, over 3 weeks now, every day, front thigh, groin, coming from nerve pain, L2 disc, nerve impingement on nerver root, pain in back, but also redirecting to front thigh, has brought me to tears, no painkillers have worked
I believe I have posted my history with regard to this recent episode of severe pain, over 3 weeks now, every day, front thigh, groin, coming from nerve pain, L2 disc, nerve impingement on nerver root, pain in back, but also redirecting to front thigh, has brought me to tears, no painkillers have worked
arvine
in
Pain Concern
11 months ago
Boron
Hi AllHas anyone heard of taking boron supplements instead of alendronic acid? (I have some osteopenia and am on prednisolone for PMR.) Many thanks
Hi AllHas anyone heard of taking boron supplements instead of alendronic acid? (I have some osteopenia and am on prednisolone for PMR.) Many thanks
CaraDee
in
PMRGCAuk
8 months ago
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