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Experiences with
Prostate-specific antigen (PSA)
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Trying to make sense of things
Can anyone explain why some people have Gleason 8 PC, high
PSA
and have metastatic disease, yet some with Gleason 9 and 10 have low-ish
PSA
(as far as PC goes) and no obvious metastatic disease (confirmed by PSMA)?
Can anyone explain why some people have Gleason 8 PC, high
PSA
and have metastatic disease, yet some with Gleason 9 and 10 have low-ish
PSA
(as far as PC goes) and no obvious metastatic disease (confirmed by PSMA)?
EvFC
in
Advanced Prostate Cancer
2 months ago
Could This Alternative Regiment Be Decelerating My PSA?
Between Summer of 2021 and Summer of 2023--two solid years--my
PSA
went from 11.5 to 15.3, roughly two points per year.
Between Summer of 2021 and Summer of 2023--two solid years--my
PSA
went from 11.5 to 15.3, roughly two points per year.
back2health
in
Advanced Prostate Cancer
1 month ago
Am I becoming castrate resistant on orgovix?
I was doing well low T <10 and
PSA
.02. I had a lady friend come visit and took a 40 day break from the Orgovyx. I retested the day she left and my T jumped up to 502 and my
PSA
jumped up to .312. That was last August 2023. Dec. 2023 the T went back to 13 and
PSA
.06.
I was doing well low T <10 and
PSA
.02. I had a lady friend come visit and took a 40 day break from the Orgovyx. I retested the day she left and my T jumped up to 502 and my
PSA
jumped up to .312. That was last August 2023. Dec. 2023 the T went back to 13 and
PSA
.06.
Startech
in
Advanced Prostate Cancer
4 months ago
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Phase 1 trial shows promising results for fractionated dose of 225Ac-J591 in PCa treatment
The fractionated dosing achieved promising results with 95% of patients experiencing any
PSA
decline and 71% achieving a PSA50 response. In contrast, the multiple cycles cohort saw 72% of patients with any
PSA
decline and 28% achieving a PSA50 response...fractionate good!
The fractionated dosing achieved promising results with 95% of patients experiencing any
PSA
decline and 71% achieving a PSA50 response. In contrast, the multiple cycles cohort saw 72% of patients with any
PSA
decline and 28% achieving a PSA50 response...fractionate good!
Maxone73
in
Advanced Prostate Cancer
2 months ago
PSA update
PSA
960 high volume metastatic. Lowest
PSA
nadir 0.1 Aug 2022. Slowly rising Nov. 2023 was 0.21, Feb 2024 0.41....Doubling time 3.1 months . On Lupron and 1000 mg Abiraterone with 0.5 Dexamethasone . Darn.
PSA
960 high volume metastatic. Lowest
PSA
nadir 0.1 Aug 2022. Slowly rising Nov. 2023 was 0.21, Feb 2024 0.41....Doubling time 3.1 months . On Lupron and 1000 mg Abiraterone with 0.5 Dexamethasone . Darn.
wolverine11
in
Advanced Prostate Cancer
5 months ago
Minor psa increase again
Just over 12 months since adt finished. All clear at <0.01 2 months ago when it started to rise to 0.03 then 4 weeks later 0.05 now 0.07. Have Dr's app in 3 weeks which will probably be a referral back to oncologist. Do we need to wait until 2.0 then a PET scan or can I be proactive now? My adt was
Just over 12 months since adt finished. All clear at <0.01 2 months ago when it started to rise to 0.03 then 4 weeks later 0.05 now 0.07. Have Dr's app in 3 weeks which will probably be a referral back to oncologist. Do we need to wait until 2.0 then a PET scan or can I be proactive now? My adt was
Runner1957
in
Prostate Cancer Network
26 days ago
Please share your experiences and thoughts.
My
psa
is undetectable. I am on ADT vacation now for the last 7 months. Should I start ADT now or wait untill
psa
is detectable? 1. SPLEEN: No new suspicious uptake. Slightly decreased conspicuity of mild uptake at the splenic hilum, image 168, SUV 9.9, previously 10.9. 2.
My
psa
is undetectable. I am on ADT vacation now for the last 7 months. Should I start ADT now or wait untill
psa
is detectable? 1. SPLEEN: No new suspicious uptake. Slightly decreased conspicuity of mild uptake at the splenic hilum, image 168, SUV 9.9, previously 10.9. 2.
Ahk1
in
Advanced Prostate Cancer
10 days ago
PSA vs Testosterone plot has large scatter, but still confirms Morgentaler's Saturation Model.
than T= 250 ng/dL will not increase the
PSA
level any further.
than T= 250 ng/dL will not increase the
PSA
level any further.
janebob99
in
Prostate Cancer Network
4 months ago
Rising PSA
Clear everything in 2017 … but 6 months after surgery rising
PSA
. Casodex/Lupron/39 Rounds Radiation. Presently on Lupron/Nubeqa
PSA
rising PSMA Scan Clear CT scan with Contrast today plus Fractionated Blood Biopsy.
PSA
10.8 Waiting on CT results but Dr.
Clear everything in 2017 … but 6 months after surgery rising
PSA
. Casodex/Lupron/39 Rounds Radiation. Presently on Lupron/Nubeqa
PSA
rising PSMA Scan Clear CT scan with Contrast today plus Fractionated Blood Biopsy.
PSA
10.8 Waiting on CT results but Dr.
JolleySprings
in
Advanced Prostate Cancer
5 months ago
High PSA upon diagnosis, treatment , and outcome
Hello, Diagnosed 9 months ago with Gleason 7 unfavorable… 2 4+3 ,2 3+4, and 1 3+3 ..on one side only ..I guess my high
PSA
score made it unfavorable ,
PSA
18.
Hello, Diagnosed 9 months ago with Gleason 7 unfavorable… 2 4+3 ,2 3+4, and 1 3+3 ..on one side only ..I guess my high
PSA
score made it unfavorable ,
PSA
18.
Yokohama2023
in
Prostate Cancer Network
4 months ago
High ALT, AST number in blood work
PSA
down to 2.96 from 7.95 (initially diagnosed at 79.5).
PSA
is gradually going down which i think may be a good sign . But in todays report ALT came at 102.8U/l and AST at 67.8 U/l . In last report 2 months back it was 27.3 and 23.8 respectively for ALT and AST .
PSA
down to 2.96 from 7.95 (initially diagnosed at 79.5).
PSA
is gradually going down which i think may be a good sign . But in todays report ALT came at 102.8U/l and AST at 67.8 U/l . In last report 2 months back it was 27.3 and 23.8 respectively for ALT and AST .
jeetu_g27
in
Advanced Prostate Cancer
23 days ago
How do I update my bio?
My good new is that my
PSA
has been 0.01 "nearly undetectable" for more than a year.
My good new is that my
PSA
has been 0.01 "nearly undetectable" for more than a year.
happycamperguy
in
Advanced Prostate Cancer
25 days ago
radiation treatment delayed
I decided to forgo radiation since
PSA
remains non detectable. Maybe just lucky but I felt no need for radiation on less there was a positive pc result. Good luck everyone
I decided to forgo radiation since
PSA
remains non detectable. Maybe just lucky but I felt no need for radiation on less there was a positive pc result. Good luck everyone
thansen535
in
Advanced Prostate Cancer
3 months ago
radiation treatment delayed
I decided to forgo radiation since
PSA
remains non detectable. Maybe just lucky but I felt no need for radiation on less there was a positive pc result. Good luck everyone
I decided to forgo radiation since
PSA
remains non detectable. Maybe just lucky but I felt no need for radiation on less there was a positive pc result. Good luck everyone
thansen535
in
Advanced Prostate Cancer
3 months ago
Metastatic PC that produces no or low PSA
Hi All, Looking to connect with people with metastatic PC that produces no or low
PSA
I am 44 and was diagnosed with PC with a bone metastasis grade 4+5. My
PSA
at time of diagnosis was 0.54. I’m undergoing PEACE 1 protocol treatment. Finish RT and Doxetaxel still on Zytiga.
Hi All, Looking to connect with people with metastatic PC that produces no or low
PSA
I am 44 and was diagnosed with PC with a bone metastasis grade 4+5. My
PSA
at time of diagnosis was 0.54. I’m undergoing PEACE 1 protocol treatment. Finish RT and Doxetaxel still on Zytiga.
Jumpingbellybeans
in
Advanced Prostate Cancer
3 months ago
The continuing saga of Scout and Coco, Not all change is welcome.
After cruising along with an Undetectable
PSA
for a little over 2+ years, my recent test results indicate a
PSA
of 0.03 and my Testosterone jumped from <7 to 13. The good news is my T is coming back but it looks like my PCa may be reawaking as well.
After cruising along with an Undetectable
PSA
for a little over 2+ years, my recent test results indicate a
PSA
of 0.03 and my Testosterone jumped from <7 to 13. The good news is my T is coming back but it looks like my PCa may be reawaking as well.
Scout4answers
in
Advanced Prostate Cancer
21 days ago
PSA levels will increase over time, depending on the level of testosterone - Part I
For example, doubling the testosterone level from 100 to 200 ng/dL makes the
PSA
increase at double the rate.
For example, doubling the testosterone level from 100 to 200 ng/dL makes the
PSA
increase at double the rate.
janebob99
in
Prostate Cancer Network
5 months ago
What is done in this case ? ADT not working
In may of 2011 the
PSA
and Biopsy showed that I had an agressive cancer with Gleason 8 so my prostate was extracted and after this I received radiotherapy.
In may of 2011 the
PSA
and Biopsy showed that I had an agressive cancer with Gleason 8 so my prostate was extracted and after this I received radiotherapy.
Alfy47
in
Prostate Cancer Network
3 months ago
Three month post SBRT PSA
Just got my
PSA
and testosterone three months post SBRT and in month 4 of Orgovyx.
PSA
is 0.09 ng/ml down from 7.8 Testosterone is 14.25 ng/dL Just had the blood draw 2 hours ago and results were pushed to my portal. Meet with my RO in 10 days.....I am THRILLED with the results!
Just got my
PSA
and testosterone three months post SBRT and in month 4 of Orgovyx.
PSA
is 0.09 ng/ml down from 7.8 Testosterone is 14.25 ng/dL Just had the blood draw 2 hours ago and results were pushed to my portal. Meet with my RO in 10 days.....I am THRILLED with the results!
ToolBeltZia
in
Prostate Cancer Network
4 months ago
Update, small cell
Gleason 9,
PSA
167. Spread to pelvic lymph nodes. Not shown any where else but oncologist was sure it had given high
PSA
. He had chemotherapy, 37 radiotherapies and Lupron for 3 years.
Gleason 9,
PSA
167. Spread to pelvic lymph nodes. Not shown any where else but oncologist was sure it had given high
PSA
. He had chemotherapy, 37 radiotherapies and Lupron for 3 years.
Fdccs
in
Advanced Prostate Cancer
2 months ago
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