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Experiences with
Prostate-specific antigen (PSA)
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Unsure of best option in early prostate cancer diagnosis.
I have had
PSA
tests annually for 10 years and in Oct 2023 had an elevated 6.42 result. Was referred to a urologist, whom performed a DRE. There was prostate enlargement but no tumor discovered through DRE. After discussing several options, I decided to have a biopsy on Nov 21, 2023.
I have had
PSA
tests annually for 10 years and in Oct 2023 had an elevated 6.42 result. Was referred to a urologist, whom performed a DRE. There was prostate enlargement but no tumor discovered through DRE. After discussing several options, I decided to have a biopsy on Nov 21, 2023.
cobrasc429
in
Advanced Prostate Cancer
3 months ago
Any Curative Treatments after RT as Sole Primary Treatment?
PSA
has been rising, but not officially nadir plus 2, but the old 3 rises in a row has been reached. If there is nothing curative to be done, do you just wait until nadir plus 2 is reached or something shows up on a scan? is there some way to be proactive? Tall_Allen didn't you have initial RT?
PSA
has been rising, but not officially nadir plus 2, but the old 3 rises in a row has been reached. If there is nothing curative to be done, do you just wait until nadir plus 2 is reached or something shows up on a scan? is there some way to be proactive? Tall_Allen didn't you have initial RT?
Researcher50
in
Advanced Prostate Cancer
4 months ago
Pluvicto Failed - Next step
Even though my
PSA
is rising, he said we should take a 30- or 60-day rest to try to strengthen my body through blood infusions to see where we go next. Have any of you been at this crossroad and what did you decide to do.
Even though my
PSA
is rising, he said we should take a 30- or 60-day rest to try to strengthen my body through blood infusions to see where we go next. Have any of you been at this crossroad and what did you decide to do.
Hidden
in
Advanced Prostate Cancer
6 months ago
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Shawty got low, low, low, & the Beat goes On. PSA update!
https://youtu.be/ckKFxMw6z0c?si=uEmAdIKQg-1jg-Hw https://youtu.be/9lkfrtztqEY?si=EBG_OJ3pB1LcBRQ0 I dunno why it's still droppin' almost a year post 28 IMRTs but I ain't gon complain 😜 Maybe I have Someone to watch over me https://youtu.be/g8J2Gb-hMIY?si=FYnNKgYTgkpdC4ud Life is Beautiful https
https://youtu.be/ckKFxMw6z0c?si=uEmAdIKQg-1jg-Hw https://youtu.be/9lkfrtztqEY?si=EBG_OJ3pB1LcBRQ0 I dunno why it's still droppin' almost a year post 28 IMRTs but I ain't gon complain 😜 Maybe I have Someone to watch over me https://youtu.be/g8J2Gb-hMIY?si=FYnNKgYTgkpdC4ud Life is Beautiful https
dockam
in
Advanced Prostate Cancer
2 months ago
My experience with Docetaxel
My
PSA
at the start was 17. I won’t know the
PSA
result after the 10th since I just had the 10 treatment 3 days ago but here are my readings from October 23-May 24 being checked every 3 weeks 17, 9.6, 6.4, 3.6,2.8, 1.8, 1.6, 1.6, 1.4, and the last 1.6.
My
PSA
at the start was 17. I won’t know the
PSA
result after the 10th since I just had the 10 treatment 3 days ago but here are my readings from October 23-May 24 being checked every 3 weeks 17, 9.6, 6.4, 3.6,2.8, 1.8, 1.6, 1.6, 1.4, and the last 1.6.
Oct18
in
Advanced Prostate Cancer
2 days ago
Chemotherapy or Pluvicto
PSA
has been doubling since I failed Zytiga. Last scans show progression. I am offered chemo or a trial with Pluvicto. The cancer is throughout my bones. What should I do. I have had chemo at the beginning of this journey and it worked then.
PSA
has been doubling since I failed Zytiga. Last scans show progression. I am offered chemo or a trial with Pluvicto. The cancer is throughout my bones. What should I do. I have had chemo at the beginning of this journey and it worked then.
Islandboy2021
in
Advanced Prostate Cancer
7 months ago
Add Nubeqa to Orgovyx?
PSA
was 3.78 in Dec 2023. PSMA PET then showed cancer growing in prostate, shrinking in pelvic node, but spread to an abdominal node. I have started ADT with Orgovyx (relugolix) and want to add an ARI. The urologist wants to use the ARI Erleada (apalutamide).
PSA
was 3.78 in Dec 2023. PSMA PET then showed cancer growing in prostate, shrinking in pelvic node, but spread to an abdominal node. I have started ADT with Orgovyx (relugolix) and want to add an ARI. The urologist wants to use the ARI Erleada (apalutamide).
vintage42
in
Advanced Prostate Cancer
3 months ago
Pluvicto failed - what is next?
I just got my most recent
PSA
test after my fourth injection and my
PSA
has now gone from 20 to 30. Also my PSMA scan says that my cancer is no more stable and on the move with more tracers. Still just in the bones. Pluvicto was brutal on my body. Extreme fatigue, dry mouth, terrible.
I just got my most recent
PSA
test after my fourth injection and my
PSA
has now gone from 20 to 30. Also my PSMA scan says that my cancer is no more stable and on the move with more tracers. Still just in the bones. Pluvicto was brutal on my body. Extreme fatigue, dry mouth, terrible.
Hidden
in
Advanced Prostate Cancer
8 months ago
biopsy - fragmented cores and progression risk
(
PSA
always <10 and first 2 years <5) See below : any comment in this report would be useful albeit hindsight as now on 18-24 months of HT following radiotherapy and negative PSMA/Pet. Any use in genomics ?
(
PSA
always <10 and first 2 years <5) See below : any comment in this report would be useful albeit hindsight as now on 18-24 months of HT following radiotherapy and negative PSMA/Pet. Any use in genomics ?
SimMartin
in
Advanced Prostate Cancer
3 months ago
Starting the journey Interested in comments Gleason 5+4 Met to Lymph and Maybe ribs
I have just started this journey, and am deciding on treatments now. 60 years young with a Gleason 5+4
PSA
hovering around 7. My PSMA PET showed one lymph near pelvis for sure, and possibly a rib neat top on left side.
I have just started this journey, and am deciding on treatments now. 60 years young with a Gleason 5+4
PSA
hovering around 7. My PSMA PET showed one lymph near pelvis for sure, and possibly a rib neat top on left side.
Saladman50
in
Advanced Prostate Cancer
12 days ago
Treatment options
PSA
was 77 in Jan and dropped to 23 after starting ADT treatment and already feeling better with much less urinary symptoms. I was advised to start radiation treatment but doctor advised to wait for PSMA PET scan (Still waiting for scan).
PSA
was 77 in Jan and dropped to 23 after starting ADT treatment and already feeling better with much less urinary symptoms. I was advised to start radiation treatment but doctor advised to wait for PSMA PET scan (Still waiting for scan).
mtechguy
in
Advanced Prostate Cancer
13 days ago
Early Results of Estrogen PATCH trial - 1
Stage T3 (73%) and Stage T4 (14%), baseline
PSA
= 35 ng/mL. The upper chart shows the % change in a given measurement after 12 months of treatment, comparing Lupron ADT to high-dose transdermal estrogen (TDE) patch.
Stage T3 (73%) and Stage T4 (14%), baseline
PSA
= 35 ng/mL. The upper chart shows the % change in a given measurement after 12 months of treatment, comparing Lupron ADT to high-dose transdermal estrogen (TDE) patch.
janebob99
in
Prostate Cancer Network
2 months ago
Treatment going forward
PSA
remains about 3.4. Total of 9/30 positive mostly 3+4=7 20% pattern 4. PSMA PET/CT reports focal uptake at left posterior margin of prostate non-specific possibly correlating with primary imaging. Max SUV is 3.4.
PSA
remains about 3.4. Total of 9/30 positive mostly 3+4=7 20% pattern 4. PSMA PET/CT reports focal uptake at left posterior margin of prostate non-specific possibly correlating with primary imaging. Max SUV is 3.4.
good2go
in
Advanced Prostate Cancer
3 months ago
Pancreas problems after RT for prostate
My
PSA
levels have dropped and progress seems OK. I have also had M.E. and fibromyalgia for over 25 years and, as part of that, IBS. Since starting the hormone therapy and radiotherapy I became more and more constipated and my tolerance of foods (especially hi fibre) increasingly difficult.
My
PSA
levels have dropped and progress seems OK. I have also had M.E. and fibromyalgia for over 25 years and, as part of that, IBS. Since starting the hormone therapy and radiotherapy I became more and more constipated and my tolerance of foods (especially hi fibre) increasingly difficult.
Nomojo56
in
Pelvic Radiation Disease Association
18 days ago
Xtandi--Eligibility
Hello, I have been taking Xtandi since June 2022, It has taken my
PSA
down to <.01 (less than) and so far has kept it there. Which I am very grateful! I am self pay and not old enough to have Medicare (just turned 64). I have recieved the Xtandi thru Astellas pharmacy in Texas.
Hello, I have been taking Xtandi since June 2022, It has taken my
PSA
down to <.01 (less than) and so far has kept it there. Which I am very grateful! I am self pay and not old enough to have Medicare (just turned 64). I have recieved the Xtandi thru Astellas pharmacy in Texas.
JD-guy
in
Advanced Prostate Cancer
2 months ago
CDK 12 mutation and Immunotherapy
Hi All, My
PSA
as is starting to rise on Arbi/Dexa. I have the CDK12 mutation which is apparently known to be a drug target or to predict sensitivity to Atezolizumab (Tecentriq PD-1 Checkpoint Inhibitor), hence there is open Immunotherapy trial called BoB (NCT03767075).
Hi All, My
PSA
as is starting to rise on Arbi/Dexa. I have the CDK12 mutation which is apparently known to be a drug target or to predict sensitivity to Atezolizumab (Tecentriq PD-1 Checkpoint Inhibitor), hence there is open Immunotherapy trial called BoB (NCT03767075).
MikeMartin
in
Advanced Prostate Cancer
4 months ago
I introduce myself to you
That's it Take care of yourself, I live in France, I was born in April 1963, I am married and I stopped my professional activity 10 months ago Diagnosed 09/2019,
PSA
6.4, Biopsy: 6 Gleason 7 (3+4) right samples, 1 sample left side Gleason 8 (4+4) . Radical Prostatectomy 11/2019.
That's it Take care of yourself, I live in France, I was born in April 1963, I am married and I stopped my professional activity 10 months ago Diagnosed 09/2019,
PSA
6.4, Biopsy: 6 Gleason 7 (3+4) right samples, 1 sample left side Gleason 8 (4+4) . Radical Prostatectomy 11/2019.
graal05
in
Advanced Prostate Cancer
1 month ago
I wonder if anyone knows why or has experienced a rise on PSA level (from 70 to 274), 6 months after radiation therapy (VMAT x 26 sessions)?
This month (October), after receiving his Leuprorelin injection, Urologist advised to stop taking Bicalutamide as it is no longer effective due to hormone resistance resulting to a rise on
PSA
level. Instead, take Abiraterone Acetate with Prednisone.
This month (October), after receiving his Leuprorelin injection, Urologist advised to stop taking Bicalutamide as it is no longer effective due to hormone resistance resulting to a rise on
PSA
level. Instead, take Abiraterone Acetate with Prednisone.
Iloveyoudad
in
Advanced Prostate Cancer
7 months ago
High volume, advanced metastatic prostate cancer
When the
PSA
started to rise, his medication was switched up, a petscan was done and it demonstrated a partial response to cancer, with no advancement of the cancer and as our MO said it was still asleep and not growing.Â
When the
PSA
started to rise, his medication was switched up, a petscan was done and it demonstrated a partial response to cancer, with no advancement of the cancer and as our MO said it was still asleep and not growing.Â
lgutman
in
Advanced Prostate Cancer
3 months ago
Could PSA of 3.0 be a problem?
He was recently contacted by their hereditary cancer clinic and advised that his
PSA
had increased to 3.0 from from last years 2.5. They felt that's a little high for his age and are going to call him in for an MR and a new
PSA
test. Is this any cause for concern?
He was recently contacted by their hereditary cancer clinic and advised that his
PSA
had increased to 3.0 from from last years 2.5. They felt that's a little high for his age and are going to call him in for an MR and a new
PSA
test. Is this any cause for concern?
Hidden
in
Prostate Cancer Network
9 months ago
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