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Trying to make sense of things
Can anyone explain why some people have Gleason 8 PC, high PSA and have metastatic disease, yet some with Gleason 9 and 10 have low-ish PSA (as far as PC goes) and no obvious metastatic disease (confirmed by PSMA)? I am trying to understand this damn disease and sometimes there doesn’t seem to be any
Can anyone explain why some people have Gleason 8 PC, high PSA and have metastatic disease, yet some with Gleason 9 and 10 have low-ish PSA (as far as PC goes) and no obvious metastatic disease (confirmed by PSMA)? I am trying to understand this damn disease and sometimes there doesn’t seem to be any
EvFC
in
Advanced Prostate Cancer
5 months ago
Olaparib time to lower PSA
Hello all, Anyone know how long it take for Olaparib ro lower PSA? All I can find is that it takes 90 days to start working. Thanks
Hello all, Anyone know how long it take for Olaparib ro lower PSA? All I can find is that it takes 90 days to start working. Thanks
Seebs9
in
Advanced Prostate Cancer
5 months ago
Ct scan of abdomen and pelvis and full body bone scan?
Hello, I have been advised to get a ct scan of abdomen and pelvis with and without contrast, along with a full body bone scan prior to my next appointment with my urologist. PSA has been undetectable since completion 9/9/20 of image guided radiation to the prostate bed and lymph nodes with a 6 month
Hello, I have been advised to get a ct scan of abdomen and pelvis with and without contrast, along with a full body bone scan prior to my next appointment with my urologist. PSA has been undetectable since completion 9/9/20 of image guided radiation to the prostate bed and lymph nodes with a 6 month
realtorjohn42
in
Advanced Prostate Cancer
5 months ago
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PC related to TURP
I had a good friend, 72 yo, that had TURP recently and the tissue showed something like a 1% cancer content (he was not very technical in exactly what it was). His PSA is and has been in the 2 range, yet his doc wants to do a prostate biopsy. Normally a person with a PSA of 2 would not have an invasive
I had a good friend, 72 yo, that had TURP recently and the tissue showed something like a 1% cancer content (he was not very technical in exactly what it was). His PSA is and has been in the 2 range, yet his doc wants to do a prostate biopsy. Normally a person with a PSA of 2 would not have an invasive
Teufelshunde
in
Prostate Cancer Network
7 days ago
Stopping Prostap & Hrt, Advice required, Scared but can't do another 3 months feeling so depressed and knackered 24/7 xxx
I'm on my 4th month of Prostap injection and Hrt, I feel like I can't mentally take another 2/3 months, my appointment system is a joke at the hospital therefore I have to arrange my appointments myself and can't actually get through to anyone at the hospital, I really don't want the Prostap injection
I'm on my 4th month of Prostap injection and Hrt, I feel like I can't mentally take another 2/3 months, my appointment system is a joke at the hospital therefore I have to arrange my appointments myself and can't actually get through to anyone at the hospital, I really don't want the Prostap injection
Victoria101986
in
Endometriosis UK
1 year ago
A Phase 1, Open-Label, Multicenter Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer
I have a choice between this trial and a BAT trial. I’m already preferential to BAT, but without being too hasty, I wanted to see if anyone here has any experience with JANX00x before deciding.
I have a choice between this trial and a BAT trial. I’m already preferential to BAT, but without being too hasty, I wanted to see if anyone here has any experience with JANX00x before deciding.
No_stone_unturned
in
Advanced Prostate Cancer
7 months ago
Not great news for hubby today. What is next?
Just updated my husband's profile so you can see his journey from 2016. Oncologist today said to continue the Abiraterone for another month and see where we are at with PSA results. Was up again today. He did have 6 rounds of targeted radiation last month, so would that cause PSA to go up. We were hoping
Just updated my husband's profile so you can see his journey from 2016. Oncologist today said to continue the Abiraterone for another month and see where we are at with PSA results. Was up again today. He did have 6 rounds of targeted radiation last month, so would that cause PSA to go up. We were hoping
Docker53
in
Advanced Prostate Cancer
5 months ago
Expanded label sought for 177Lu-PSMA-617 in prostate cancer: about time
I have already done the taxane part and I would like to see how 177Lu performs as first line...but this is also interesting, it seems more effective than a change in ARPI in castration resistant setting "Data also showed that a PSA decline of at least 50% was more than 2.5 times more frequent with 177Lu-PSMA
I have already done the taxane part and I would like to see how 177Lu performs as first line...but this is also interesting, it seems more effective than a change in ARPI in castration resistant setting "Data also showed that a PSA decline of at least 50% was more than 2.5 times more frequent with 177Lu-PSMA
Maxone73
in
Advanced Prostate Cancer
6 months ago
Some Prostate Cancer Medical Practitioners on a Chart - 2024
Advanced Prostate Cancer Consensus Conference (APCCC) 2024
You decide if you think they're any good or not. ----- Previous title history, changed due to inaccuracies or controversies: 1. Worlds top Medical Oncologists -2024 2. Worlds top Prostate Cancer Medical Practioners - 2024 3. Some
Advanced Prostate Cancer Consensus Conference (APCCC) 2024
You decide if you think they're any good or not. ----- Previous title history, changed due to inaccuracies or controversies: 1. Worlds top Medical Oncologists -2024 2. Worlds top Prostate Cancer Medical Practioners - 2024 3. Some
skiingfiend
in
Advanced Prostate Cancer
7 months ago
Full body MRI?
We’ve been reading about full body MRIs and wonder if anyone has had one after radiation treatment for prostate cancer? Can this type of test pick up micro metastases? If the full body scan was “all clear” could ADT be shortened from 2 years to a lower amount?
We’ve been reading about full body MRIs and wonder if anyone has had one after radiation treatment for prostate cancer? Can this type of test pick up micro metastases? If the full body scan was “all clear” could ADT be shortened from 2 years to a lower amount?
Oatmeal2
in
Advanced Prostate Cancer
7 months ago
My experience with Docetaxel
I know everyone doesn’t respond the same but here is my experience and what I went through with 10 rounds of chemo. Before I started I had already been on Lupron for five years, I had radiation to multiple bone Mets, took zytiga/xtandi, had Provenge and did a clinical trial. October 26 2023 I started
I know everyone doesn’t respond the same but here is my experience and what I went through with 10 rounds of chemo. Before I started I had already been on Lupron for five years, I had radiation to multiple bone Mets, took zytiga/xtandi, had Provenge and did a clinical trial. October 26 2023 I started
Oct18
in
Advanced Prostate Cancer
5 months ago
Update May 15, 2024
Hoping all is well with others on this site. UPDATE May 15 2024 I am concerned about results of the Right frontal skull SUV 5.3 previously 0.75. I have researched and really can't find any information that I can understand. Any replies would be greatly appreciated My husband had his PSMA PET/
Hoping all is well with others on this site. UPDATE May 15 2024 I am concerned about results of the Right frontal skull SUV 5.3 previously 0.75. I have researched and really can't find any information that I can understand. Any replies would be greatly appreciated My husband had his PSMA PET/
MsHope
in
Advanced Prostate Cancer
6 months ago
What comes after, what comes next?
I have posted a few times about my dad. Stage 4, mets to 8+ bones at time of diagnosis, PSA at 137 (10/22.) Lupron twice a year, Bicalutamide, failed at 7 months, Xtandi failed at 4 months, currently on Zytiga. We met with my dad’s oncologist on 4/24. My Dad’s PSA dropped from 2.47-1.46 and pain has
I have posted a few times about my dad. Stage 4, mets to 8+ bones at time of diagnosis, PSA at 137 (10/22.) Lupron twice a year, Bicalutamide, failed at 7 months, Xtandi failed at 4 months, currently on Zytiga. We met with my dad’s oncologist on 4/24. My Dad’s PSA dropped from 2.47-1.46 and pain has
lgutman
in
Advanced Prostate Cancer
5 months ago
Phase 1 trial shows promising results for fractionated dose of 225Ac-J591 in PCa treatment
The fractionated dosing achieved promising results with 95% of patients experiencing any PSA decline and 71% achieving a PSA50 response. In contrast, the multiple cycles cohort saw 72% of patients with any PSA decline and 28% achieving a PSA50 response...fractionate good! https://www.urotoday.com/conference-highlights
The fractionated dosing achieved promising results with 95% of patients experiencing any PSA decline and 71% achieving a PSA50 response. In contrast, the multiple cycles cohort saw 72% of patients with any PSA decline and 28% achieving a PSA50 response...fractionate good! https://www.urotoday.com/conference-highlights
Maxone73
in
Advanced Prostate Cancer
5 months ago
177Lu-PSMA-617: Trial shows it's more effective than changing ARPIs
"Patients who enrolled in the trial were assigned to either a change in ARPI, for example from abiraterone to enzalutamide or vice versa, or 177Lu-PSMA-617, a prostate-specific antigen (PSMA)-targeted radioligand therapy. This analysis found that treatment with 177Lu-PSMA-617 prolonged radiographic progression-free
"Patients who enrolled in the trial were assigned to either a change in ARPI, for example from abiraterone to enzalutamide or vice versa, or 177Lu-PSMA-617, a prostate-specific antigen (PSMA)-targeted radioligand therapy. This analysis found that treatment with 177Lu-PSMA-617 prolonged radiographic progression-free
Maxone73
in
Advanced Prostate Cancer
5 months ago
Wife of Newly Diagnosed Husband - PSMA questions
Hi Everyone, We found out two weeks ago that my husband has high grade prostate cancer. He is 59. PSA 5.9. Gleason 4+5, 4+3 and 3+4. There was perineural invasion in one sample and intraductal in another. He has had an MRI and a CT scan, as well. He is scheduled for a bone scan next week. No prostate
Hi Everyone, We found out two weeks ago that my husband has high grade prostate cancer. He is 59. PSA 5.9. Gleason 4+5, 4+3 and 3+4. There was perineural invasion in one sample and intraductal in another. He has had an MRI and a CT scan, as well. He is scheduled for a bone scan next week. No prostate
EvFC
in
Advanced Prostate Cancer
6 months ago
Prostate cancer made to my brain, skull and muscles in my head
Well, that’s something isn’t it? Have you ever seen that much cancer in someone’s head? Both my radiation oncologist and my and my regular oncologist at City of Hope said that this is something very unusual for prostate cancer to do. So there getting all of it for research to investigate what the
Well, that’s something isn’t it? Have you ever seen that much cancer in someone’s head? Both my radiation oncologist and my and my regular oncologist at City of Hope said that this is something very unusual for prostate cancer to do. So there getting all of it for research to investigate what the
Gl448
in
Advanced Prostate Cancer
8 months ago
PSA following Lupron and question on scans
hi all, I am so happy to report that my dad has really improved following terrible side effects with his radiation treatment. I have posted before -he was having awful GI side effects which seemed to get worse following radiation completion. But this is all subsided which we are grateful for. dad
hi all, I am so happy to report that my dad has really improved following terrible side effects with his radiation treatment. I have posted before -he was having awful GI side effects which seemed to get worse following radiation completion. But this is all subsided which we are grateful for. dad
alysona828
in
Advanced Prostate Cancer
6 months ago
CRS4PC and Zytiga side effects ?
My hubby is 69 and recently started Zytiga three weeks ago and it seems that he has developed moderate fatigue and low appetite since one week ago. I’m wondering if this could be a side effect of the Zytiga or if anyone thinks it’s an immunity infection attack.
My hubby is 69 and recently started Zytiga three weeks ago and it seems that he has developed moderate fatigue and low appetite since one week ago. I’m wondering if this could be a side effect of the Zytiga or if anyone thinks it’s an immunity infection attack.
Corgi16
in
Advanced Prostate Cancer
8 months ago
radiation treatment delayed
2 years since prostatectomy. Psa still non detectable. Will get it checked again in 6 months or 1 year depending on urologist suggestion. I feel blessed since standard protocol was radiation to the pelvic area had 6 Month Lupron shot since they found positive pc in limp nodes and tissue extracted.
2 years since prostatectomy. Psa still non detectable. Will get it checked again in 6 months or 1 year depending on urologist suggestion. I feel blessed since standard protocol was radiation to the pelvic area had 6 Month Lupron shot since they found positive pc in limp nodes and tissue extracted.
thansen535
in
Advanced Prostate Cancer
5 months ago
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