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Should go into the OMAHA2a ODM-208 (MK-5684-004): phase 3 trial?
I had my 3 monthly OC visit last week. Blood test is showing 0.3 up from 0.15 six weeks ago. MO is suggesting that I should go into the ODM-208 (MK-5684): phase 3 trial if PSA rises above 1.0. PSA of 1.0 or above is a entry requirement for the trial, presumable to be sure that my current treatment
I had my 3 monthly OC visit last week. Blood test is showing 0.3 up from 0.15 six weeks ago. MO is suggesting that I should go into the ODM-208 (MK-5684): phase 3 trial if PSA rises above 1.0. PSA of 1.0 or above is a entry requirement for the trial, presumable to be sure that my current treatment
LakeT
in
Advanced Prostate Cancer
4 days ago
Had Pet Scan, PSA rising 0.77 Found Liver Metastases, Am I a dead man? What can I do?
Going for MRI and Biopsy What can I do?
Going for MRI and Biopsy What can I do?
Shorehousejam
in
Advanced Prostate Cancer
4 days ago
Following SOC here in BC Canada
I am currently at the CRPC stage of my disease. About 7 years since diagnosis. Started with ADT and Docetaxel. Was able to be castrate sensitive for 4.5 years. Tried to add Abiraterone and it failed after a couple of months. Had Radium 223 and it was okay but did nothing to the PSA. Cancer kept progressing
I am currently at the CRPC stage of my disease. About 7 years since diagnosis. Started with ADT and Docetaxel. Was able to be castrate sensitive for 4.5 years. Tried to add Abiraterone and it failed after a couple of months. Had Radium 223 and it was okay but did nothing to the PSA. Cancer kept progressing
Islandboy2021
in
Advanced Prostate Cancer
6 days ago
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Active Surveillance?
Hello everyone, I am 72 and have been on active surveillance for prostate cancer since I was diagnosed in August 2021 but probably had it prior to my first MRI in 2020. I have had 2 biopsies and 5 MRI's and countless PSA tests. First bx showed 3 cores at 3+3 and 2 cores suspicious, confirmatory bx a
Hello everyone, I am 72 and have been on active surveillance for prostate cancer since I was diagnosed in August 2021 but probably had it prior to my first MRI in 2020. I have had 2 biopsies and 5 MRI's and countless PSA tests. First bx showed 3 cores at 3+3 and 2 cores suspicious, confirmatory bx a
ironmanburg
in
Prostate Cancer Network
7 days ago
MRI prior to Radiation Treatments + HT
My PSA has risen over nearly 5.5 years since my prostatectomy from Undetectable to 0.3. I was referred to an RO who, after reviewing my test results and prior history, indicated that there were some "cells left behind" near the prostate bed, even though they tried to get at them unsuccessfully during
My PSA has risen over nearly 5.5 years since my prostatectomy from Undetectable to 0.3. I was referred to an RO who, after reviewing my test results and prior history, indicated that there were some "cells left behind" near the prostate bed, even though they tried to get at them unsuccessfully during
brilliant17
in
Advanced Prostate Cancer
8 days ago
Starting the journey Interested in comments Gleason 5+4 Met to Lymph and Maybe ribs
I have just started this journey, and am deciding on treatments now. 60 years young with a Gleason 5+4 PSA hovering around 7. My PSMA PET showed one lymph near pelvis for sure, and possibly a rib neat top on left side. My medical oncologist ordered a bone scan, which showed nothing on the left side
I have just started this journey, and am deciding on treatments now. 60 years young with a Gleason 5+4 PSA hovering around 7. My PSMA PET showed one lymph near pelvis for sure, and possibly a rib neat top on left side. My medical oncologist ordered a bone scan, which showed nothing on the left side
Saladman50
in
Advanced Prostate Cancer
8 days ago
Waiting for Mr. T
I had an interesting development this week in my PCa journey. I went in for my quarterly hospital visit, which would normally include blood tests, meeting with my medical oncologist, and my last 3-month injection of Eligard. Blood tests were great, PSA and testosterone still undetectable. My MO decided
I had an interesting development this week in my PCa journey. I went in for my quarterly hospital visit, which would normally include blood tests, meeting with my medical oncologist, and my last 3-month injection of Eligard. Blood tests were great, PSA and testosterone still undetectable. My MO decided
Atdabeach
in
Advanced Prostate Cancer
8 days ago
Update recent PSMA
Docs did it to me again with the usual bad news. Uptake in new lymph node locations in pelvis. the radiotherapy failed, and preclude more treatment on new nodal areas. (according to Docs.) So expect to add to ADT, abi or enza or darolutamide in a short while, with PSA going up on a fast double.
Docs did it to me again with the usual bad news. Uptake in new lymph node locations in pelvis. the radiotherapy failed, and preclude more treatment on new nodal areas. (according to Docs.) So expect to add to ADT, abi or enza or darolutamide in a short while, with PSA going up on a fast double.
kainasar
in
Advanced Prostate Cancer
8 days ago
Newly Diagnosed Prostate Cancer
Hi, I am new here. I came to this site because my husband was just diagnosed with prostate cancer last week. MRI PI RAS 5 with an extracapsular extension, cores 4/12 positive, Gleason 7 (4+3), and PSA 4.8 (PSA 2.2 in 2022). No involvements with lymph nodes and bones on MRI. All of these seem to put
Hi, I am new here. I came to this site because my husband was just diagnosed with prostate cancer last week. MRI PI RAS 5 with an extracapsular extension, cores 4/12 positive, Gleason 7 (4+3), and PSA 4.8 (PSA 2.2 in 2022). No involvements with lymph nodes and bones on MRI. All of these seem to put
kiyo
in
Advanced Prostate Cancer
9 days ago
First BAT cycle results: what next?
I started my first BAT cycle on 3-12-24, originally designed to last for 32 days.
PSA was 0.5
and I injected 50 mg eod of T propionate and .625 mg of letrozole every 3rd day to inhibit conversion of T to E2. Here are my blood test results during the cycle followed by a couple of questions:
I started my first BAT cycle on 3-12-24, originally designed to last for 32 days.
PSA was 0.5
and I injected 50 mg eod of T propionate and .625 mg of letrozole every 3rd day to inhibit conversion of T to E2. Here are my blood test results during the cycle followed by a couple of questions:
Ichthus316
in
Fight Prostate Cancer
9 days ago
Treatment options
I am 47 years old diagnosed with PC last month with Gleason score 9(5,4) and was advised ADT treatment with Bicalutamide and followed by Lupron 30 mg after two weeks. PSA was 77 in Jan and dropped to 23 after starting ADT treatment and already feeling better with much less urinary symptoms. I was advised
I am 47 years old diagnosed with PC last month with Gleason score 9(5,4) and was advised ADT treatment with Bicalutamide and followed by Lupron 30 mg after two weeks. PSA was 77 in Jan and dropped to 23 after starting ADT treatment and already feeling better with much less urinary symptoms. I was advised
mtechguy
in
Advanced Prostate Cancer
9 days ago
What is done in this case ? ADT not working
In may of 2011 the PSA and Biopsy showed that I had an agressive cancer with Gleason 8 so my prostate was extracted and after this I received radiotherapy. Since during the following 9 years my psa continued very low, I suspended checking it and last september I received the surprise that it had increased
In may of 2011 the PSA and Biopsy showed that I had an agressive cancer with Gleason 8 so my prostate was extracted and after this I received radiotherapy. Since during the following 9 years my psa continued very low, I suspended checking it and last september I received the surprise that it had increased
Alfy47
in
Prostate Cancer Network
9 days ago
Positive medical check update April 2024
Last days I’ve had couple of blood tests, ultra sound, annual PSMA Pet/CT and a meeting with my urologist. My last Lupron shot was Oct 2023. Blood values are all very ok, PSA undetectable, Testo less 0.1 ng/ML and PSMA Pet/CT and ultra sound clean, no recurrence, no metastases. I’m more than thankful
Last days I’ve had couple of blood tests, ultra sound, annual PSMA Pet/CT and a meeting with my urologist. My last Lupron shot was Oct 2023. Blood values are all very ok, PSA undetectable, Testo less 0.1 ng/ML and PSMA Pet/CT and ultra sound clean, no recurrence, no metastases. I’m more than thankful
Nusch
in
Advanced Prostate Cancer
9 days ago
Muscle loss
I'm sure this is a beaten horse topic, but I am unable to perform my previous weight training insofar as weight and stamina. I'm on eligard every 3 months and nightly erleada pill. Can I incorporate creatine monohydrate without effecting my PSA or exacerbating my BPH? I'm Stage 4, Gleason 9, mets to
I'm sure this is a beaten horse topic, but I am unable to perform my previous weight training insofar as weight and stamina. I'm on eligard every 3 months and nightly erleada pill. Can I incorporate creatine monohydrate without effecting my PSA or exacerbating my BPH? I'm Stage 4, Gleason 9, mets to
Mrtewills
in
Advanced Prostate Cancer
10 days ago
Eligard
My PSA keep rising. Today, PSA went up to 2.25.1 from 1.1 (March). Doctor told me that he never had a patient Eligard does not work at all at the beginning. He asked me to go thru with PSMA scan and start to take Xtandi. He said there is a possibility I may also go thru with a testicle removal surgery
My PSA keep rising. Today, PSA went up to 2.25.1 from 1.1 (March). Doctor told me that he never had a patient Eligard does not work at all at the beginning. He asked me to go thru with PSMA scan and start to take Xtandi. He said there is a possibility I may also go thru with a testicle removal surgery
Domas
in
Advanced Prostate Cancer
11 days ago
Dad with Advanced PCA :(
Hi everyone, I am new here and appreciate any assistance that could help my father. My dad is 73 years of age. Over the last few weeks we have gone from a raised PSA level 8.9 (up from 6 in 2022 and 2021, 5.1 in 2020), Negative DRE, to an MRI (PIRADS 5, SAG T2) to a positive biopsy (10 cores taken,
Hi everyone, I am new here and appreciate any assistance that could help my father. My dad is 73 years of age. Over the last few weeks we have gone from a raised PSA level 8.9 (up from 6 in 2022 and 2021, 5.1 in 2020), Negative DRE, to an MRI (PIRADS 5, SAG T2) to a positive biopsy (10 cores taken,
MissMel2024
in
Advanced Prostate Cancer
11 days ago
Enlarged Lymph Nodes on MRI and CT
Hello, new to this. Never posted before, hoping for some insight. Gleason 7 (4+3) PSA 6. Bone scan clear but lymphadenopathy in groin nodes (inguinal; iliac nodes). Does this mean spread? Being sent for a PET Scan Friday.
Hello, new to this. Never posted before, hoping for some insight. Gleason 7 (4+3) PSA 6. Bone scan clear but lymphadenopathy in groin nodes (inguinal; iliac nodes). Does this mean spread? Being sent for a PET Scan Friday.
Blue1320
in
Prostate Cancer Network
11 days ago
Tripple therapy - ADT+Lynparza+Xtandi
I just started Lynparza in addition to Xtandi and Loupron. I don’t have a BRCA mutation, but I was told that Lynparza may be beneficial regardless. I finished cycle of Jevtana (7 infusions) and Xtandi. My PSA was 0.74, but now it has increased to 2.3. All other tretments and history are in my bio. The
I just started Lynparza in addition to Xtandi and Loupron. I don’t have a BRCA mutation, but I was told that Lynparza may be beneficial regardless. I finished cycle of Jevtana (7 infusions) and Xtandi. My PSA was 0.74, but now it has increased to 2.3. All other tretments and history are in my bio. The
venecia1983
in
Advanced Prostate Cancer
11 days ago
Rising PSA
Going into 7 years. No prostate. ADT on and off. Recently while on Lupron & NUBEQA PSA continues to rise. Now at 10.1 and Testosterone nondectable. PSMA/PET/CT scan last weeks states no metastases present. We meet with Dr. Aggarwal next week. Last month at our visit he told us at this point “Scans
Going into 7 years. No prostate. ADT on and off. Recently while on Lupron & NUBEQA PSA continues to rise. Now at 10.1 and Testosterone nondectable. PSMA/PET/CT scan last weeks states no metastases present. We meet with Dr. Aggarwal next week. Last month at our visit he told us at this point “Scans
JolleySprings
in
Advanced Prostate Cancer
3 months ago
EMBARK Trial: Combination-therapy is better.
This chart compares the risk of developing metastasis from prostate cancer, after 5 years from curative treatment, between three different arms of the EMBARK study (published in 2023): (1) Lupron monotherapy; (2) Enzalutamide monotherapy; and (3) Enzalutamide + Lupron combination therapy. The cohort
This chart compares the risk of developing metastasis from prostate cancer, after 5 years from curative treatment, between three different arms of the EMBARK study (published in 2023): (1) Lupron monotherapy; (2) Enzalutamide monotherapy; and (3) Enzalutamide + Lupron combination therapy. The cohort
janebob99
in
Prostate Cancer Network
11 days ago
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