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Overall Survival With [177]Lu-PSMA-617 vs Cabazitaxel in Metastatic Castration-Resistant Prostate Cancer
The Lancet Oncology TAKE-HOME MESSAGE TheraP was a phase II trial that compared the efficacy of radioligand therapy with 177Lu-PSMA-617 with that of cabazitaxel in patients with metastatic castration-resistant prostate cancer who had previously received docetaxel. After a median follow-up of 35.7 months
The Lancet Oncology TAKE-HOME MESSAGE TheraP was a phase II trial that compared the efficacy of radioligand therapy with 177Lu-PSMA-617 with that of cabazitaxel in patients with metastatic castration-resistant prostate cancer who had previously received docetaxel. After a median follow-up of 35.7 months
Magnus1964
in
Advanced Prostate Cancer
5 months ago
Criteria for "my ADT has stopped working and we have to move to another"
Hello - So my third post ADT initiation (Lupron+Abi) PSA test is coming up and since it was <.1 six weeks ago, I asked how the criteria of “has stopped working” works -to my Hopkins MO and I got this - “We want to declare a therapy no longer effective when PSA is clearly going up. We look for 0.3
Hello - So my third post ADT initiation (Lupron+Abi) PSA test is coming up and since it was <.1 six weeks ago, I asked how the criteria of “has stopped working” works -to my Hopkins MO and I got this - “We want to declare a therapy no longer effective when PSA is clearly going up. We look for 0.3
jackwfrench
in
Advanced Prostate Cancer
5 months ago
Study reveals genetic chain reaction that drives the spread of prostate cancer
[i]Science keeps getting closer to stopping the spread of cancer.[/i] [i]Scout[/i] From the Male Care Prostrate news letter [i][/i] NOVEMBER 6, 2023 New research from scientists at VCU Massey Comprehensive Cancer Center and the VCU Institute of Molecular Medicine (VIMM) determined that a particular
[i]Science keeps getting closer to stopping the spread of cancer.[/i] [i]Scout[/i] From the Male Care Prostrate news letter [i][/i] NOVEMBER 6, 2023 New research from scientists at VCU Massey Comprehensive Cancer Center and the VCU Institute of Molecular Medicine (VIMM) determined that a particular
Scout4answers
in
Advanced Prostate Cancer
7 months ago
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Testosterone too high?
I recently had my quarterly PSA and T tests, following stopping 18 months of ADT (Orgovyx) in April of 2022. PSA continued to de undetectable (<0.01) and T was 761. The last quarterly T was 706. Having had an initial PC Dx of GL9, Stage 4, Decipher .76 (July 2019) should I be concerned that T is
I recently had my quarterly PSA and T tests, following stopping 18 months of ADT (Orgovyx) in April of 2022. PSA continued to de undetectable (<0.01) and T was 761. The last quarterly T was 706. Having had an initial PC Dx of GL9, Stage 4, Decipher .76 (July 2019) should I be concerned that T is
JPnSD
in
Advanced Prostate Cancer
4 months ago
HealthUnlocked Search And Reply Invisibility
HealthUnlocked is great. I enjoy the value of the material and the personalities on the MaleCare Advanced Prostate Cancer forum. I also mostly post replies, including detailed replies that could be root posts. But I was inspired to post them as a reply in the context of a discussion initiated by someone
HealthUnlocked is great. I enjoy the value of the material and the personalities on the MaleCare Advanced Prostate Cancer forum. I also mostly post replies, including detailed replies that could be root posts. But I was inspired to post them as a reply in the context of a discussion initiated by someone
JohnInTheMiddle
in
Advanced Prostate Cancer
7 months ago
Chemo Failed
My dad finished Docetaxel in November. He went to oncologist today. His PSA went from 0.58 to 2.3. Things he tried: Lupron (on for years before failed) Zytiga (worked for 18 months) Orchidectomy Then the chemo. He is not a candidate for radiation because of a previous cancer. He is going to
My dad finished Docetaxel in November. He went to oncologist today. His PSA went from 0.58 to 2.3. Things he tried: Lupron (on for years before failed) Zytiga (worked for 18 months) Orchidectomy Then the chemo. He is not a candidate for radiation because of a previous cancer. He is going to
Jshaw916
in
Advanced Prostate Cancer
4 months ago
Personal update
Ok, first blood work, 3 weeks after the last chemo of ARASENS protocol PSA is 0.39, it was 70 at diagnosis and 15 after 4-5 weeks (when I have started ARASENS) Testosterone 0.33 nmol/L well, that's it!
Ok, first blood work, 3 weeks after the last chemo of ARASENS protocol PSA is 0.39, it was 70 at diagnosis and 15 after 4-5 weeks (when I have started ARASENS) Testosterone 0.33 nmol/L well, that's it!
Maxone73
in
Advanced Prostate Cancer
4 months ago
Prostate cancer
My prostate condition started around eight years ago when I had urinary track infection which also led to prostatitis. Ever since then, my PSA jumped from 2 to 7.8 during the last 5 years. I had two biopsies… first one, four years ago, they detected no positive cancer cells in my prostate. However
My prostate condition started around eight years ago when I had urinary track infection which also led to prostatitis. Ever since then, my PSA jumped from 2 to 7.8 during the last 5 years. I had two biopsies… first one, four years ago, they detected no positive cancer cells in my prostate. However
Yuncoinc7148
in
Fight Prostate Cancer
5 months ago
Delay date for Lupron injection
I am due to get my third 6 monthly dose of Lupron injection in late May. I plan to travel during that time. Is there any harm if I should postpone the injection date by 2 or 3 weeks beyond the 6 months dateline?My PSA reading is currently below 0.1 ug/l. Secondly, I am contemplating going on ADT vacation
I am due to get my third 6 monthly dose of Lupron injection in late May. I plan to travel during that time. Is there any harm if I should postpone the injection date by 2 or 3 weeks beyond the 6 months dateline?My PSA reading is currently below 0.1 ug/l. Secondly, I am contemplating going on ADT vacation
John347
in
Advanced Prostate Cancer
4 months ago
Docetaxel results so far
People want to know if Docetaxel is worth doing due to the side effects. My husband just had a recent PSMA PET scan after 5 treatments and the result is compared with the same scan method done before treatment began: [i]Impression (Summary)[/i] [i]Mild improvement in subcarinal adenopathy, left lung
People want to know if Docetaxel is worth doing due to the side effects. My husband just had a recent PSMA PET scan after 5 treatments and the result is compared with the same scan method done before treatment began: [i]Impression (Summary)[/i] [i]Mild improvement in subcarinal adenopathy, left lung
Tinuriel
in
Advanced Prostate Cancer
4 months ago
PSA went up after three treatments of chemotherapy
I have had 3 Chemotherapy treatments with Docataxel. before the first treatment PSA was 89. after the first treatment PSA was 73.31.. after the second treatment PSA was 52.82. after the third treatment, PSA was 73.31.. does it make sense to take another chemotherapy treatment since the PSA has risen
I have had 3 Chemotherapy treatments with Docataxel. before the first treatment PSA was 89. after the first treatment PSA was 73.31.. after the second treatment PSA was 52.82. after the third treatment, PSA was 73.31.. does it make sense to take another chemotherapy treatment since the PSA has risen
spolyu
in
Advanced Prostate Cancer
4 months ago
Still confused about PSA and Testosterone testing
I have been reading posts here for some time and there seems to be a split between those who only get PSA tests each time they go to their doctors and those that get both tests each time. I had a baseline testosterone test before Lupron and before radiation. I am now doing my 6 month follow up and
I have been reading posts here for some time and there seems to be a split between those who only get PSA tests each time they go to their doctors and those that get both tests each time. I had a baseline testosterone test before Lupron and before radiation. I am now doing my 6 month follow up and
Mgtd
in
Advanced Prostate Cancer
5 months ago
Sterlings Reply
Please forgive the lateness but here it is:Four years after prostectomy my psa began to rise. I had eight weeks of radiation to the prostate bed. Psa returned to nondetectable for eleven years. Two years ago my psa began to rise at an alarming rate it was doubling monthly if not more. I started eligard
Please forgive the lateness but here it is:Four years after prostectomy my psa began to rise. I had eight weeks of radiation to the prostate bed. Psa returned to nondetectable for eleven years. Two years ago my psa began to rise at an alarming rate it was doubling monthly if not more. I started eligard
Praying2BHealthy
in
Advanced Prostate Cancer
5 months ago
Radiation?
just got my psa results after my first round of 4 months leuprolide and 3 months Zytiga and prednisone…..initially 18 now 0.04. Nurse told me that my MO would like to see me early to discuss more radiation( recent psma found areas of avidity only in prostate bed……initial tx was 48 grey imrt back in
just got my psa results after my first round of 4 months leuprolide and 3 months Zytiga and prednisone…..initially 18 now 0.04. Nurse told me that my MO would like to see me early to discuss more radiation( recent psma found areas of avidity only in prostate bed……initial tx was 48 grey imrt back in
Tommyj2
in
Advanced Prostate Cancer
4 months ago
Genitourinary Cancers Symposium Meeting Coverage, MedPage Today, January 2024
Latest 2024 PCa-related GuCS Meeting Coverage from MedPage Today: [i]
More Evidence That ARSIs for Prostate Cancer Differ in Cognitive Effects -More fatigue, depression, worse reaction time with enzalutamide as compared with abiraterone, January 29, 2024:
[/i] https://www.medpagetoday.com/meetingcoverage
Latest 2024 PCa-related GuCS Meeting Coverage from MedPage Today: [i]
More Evidence That ARSIs for Prostate Cancer Differ in Cognitive Effects -More fatigue, depression, worse reaction time with enzalutamide as compared with abiraterone, January 29, 2024:
[/i] https://www.medpagetoday.com/meetingcoverage
cujoe
in
Fight Prostate Cancer
4 months ago
Radical prostatectomy consultant in the south of England
I've been diagnosed with prostate cancer, quite aggressive with a Gleason of 9 (4+5). No spread has been detected on a CT scan and I'm due to have a NM bone whole body scan on Friday to detect any spread to the bones. Assuming there is no or little spread, I am keen to have a radical laparoscopic prostatectomy
I've been diagnosed with prostate cancer, quite aggressive with a Gleason of 9 (4+5). No spread has been detected on a CT scan and I'm due to have a NM bone whole body scan on Friday to detect any spread to the bones. Assuming there is no or little spread, I am keen to have a radical laparoscopic prostatectomy
MarkS
in
Prostate Cancer Network
7 months ago
Seeking Hope or Similar Stories
Hello! I just joined this community yesterday. My husband has been diagnosed with Gleason 8 prostate cancer with cribriform. PSA 18. His clinical dx is T1c. He had 6 out of12 positive biopsies. All were 4+4. 5 were 40% and 1 was 60%. He has the PSMA test on Monday. The doctor doesn’t think it has
Hello! I just joined this community yesterday. My husband has been diagnosed with Gleason 8 prostate cancer with cribriform. PSA 18. His clinical dx is T1c. He had 6 out of12 positive biopsies. All were 4+4. 5 were 40% and 1 was 60%. He has the PSMA test on Monday. The doctor doesn’t think it has
Darbydood
in
Advanced Prostate Cancer
4 months ago
Importance of ADT
Are there any good outcomes without using ADT ( hormone therapy)? I delayed it for a couple of years with bad results. My history -- [u]
2021
[/u]: Age 78. PSA was 7.79, Gleason 4+3=7. Small lesion in prostate, with perineural invasion. Had 20 IMRT for prostate. No ADT. [u]
2022
[/u]: PSA
Are there any good outcomes without using ADT ( hormone therapy)? I delayed it for a couple of years with bad results. My history -- [u]
2021
[/u]: Age 78. PSA was 7.79, Gleason 4+3=7. Small lesion in prostate, with perineural invasion. Had 20 IMRT for prostate. No ADT. [u]
2022
[/u]: PSA
vintage42
in
Advanced Prostate Cancer
5 months ago
Post treatment post ADT time to PSMA test
Where I am receiving treatment, ADT, LD Brachytherapy, LINAC radiotherapy (15) sessions.. PSMA pet scans are not available (Japan). I planning on ending adjuvant ADT therapy within a few months and am aware of the lasting effects on testosterone (will take 6-12 months for decent testosterone levels .
Where I am receiving treatment, ADT, LD Brachytherapy, LINAC radiotherapy (15) sessions.. PSMA pet scans are not available (Japan). I planning on ending adjuvant ADT therapy within a few months and am aware of the lasting effects on testosterone (will take 6-12 months for decent testosterone levels .
Yokohama2023
in
Advanced Prostate Cancer
4 months ago
Prostate-as-"PCa Factory" - Reasons for Removal?
While reading the bio of forum member, I noted the following advantage to radical prostatectomy (paraphrased):"
No more PCa factory
" As I have written in multiple posts I am enjoying very effective
triplet therapy
against my high volume metastatic prostate cancer. And because my cancer was
While reading the bio of forum member, I noted the following advantage to radical prostatectomy (paraphrased):"
No more PCa factory
" As I have written in multiple posts I am enjoying very effective
triplet therapy
against my high volume metastatic prostate cancer. And because my cancer was
JohnInTheMiddle
in
Advanced Prostate Cancer
4 months ago
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